2020 American Transplant Congress
The Evolution and Impact of ABMR Histology and Transplant Glomerulopathy in the Presence or Absence of HLA-DSA
*Purpose: After kidney transplantation, the occurrence of ABMRh (=histological picture of antibody-mediated rejection) and transplant glomerulopathy (cg) has been reported, both in the presence and…2020 American Transplant Congress
Immune Checkpoint Inhibitor Use in Kidney Transplant Recipients: Rejection Risk, Prevention and Transcriptional Signature in Allograft
1Brigham and Women's Hospital, Boston, MA, 2University of Alberta, Edmonton, AB, Canada
*Purpose: Immune checkpoint inhibitor (ICI) use has changed the landscape of cancer treatment. Several cases of acute rejection in use of ICI have been reported,…2020 American Transplant Congress
Simultaneously Detection of ddcfDNA in Plasma and Urine Assist to Determine the Type of Rejection in Renal Transplant Patients
*Purpose: The correct diagnosis and treatment of acute rejection (ABMR and TCMR) are the key to the long-term survival after renal transplantation. Renal biopsy is…2020 American Transplant Congress
Simultaneous Liver and Kidney Transplantation—The Lack of Influence of Pre-Formed DSA
Recanati-Miller Transplantation Institute, Mount Sinai Hospital, New York, New York, NY
*Purpose: It is known that renal transplant recipients with preformed donor specific antibodies (DSA) have poorer outcomes associated with episodes of acute rejection (AR) and…2020 American Transplant Congress
RNA Sequencing of Urine RNA Samples for Biomarker Discovery
*Purpose: An accurate, noninvasive assay based on urinary gene expression profiles would be a powerful tool for clinical management of kidney transplant patients. We have…2020 American Transplant Congress
Lims1 Gene and Risk of T-Cell Mediated Rejection in Kidney Transplant Recipients
*Purpose: Recent advances have provided new insights into the pathogenesis of kidney allograft rejection caused by additional antigens associated with genetic risk variant of LIM…2020 American Transplant Congress
Role of Cell Free DNA (Allosure) Testing in Recipients of Kidneys with Sub Optimal Donor Quality
*Purpose: The purpose of this study was to evaluate the role of cell-free DNA testing ( Allosure, CareDx, Brisbane , CA) during graft dysfunction in…2020 American Transplant Congress
Tissue Resident Memory T Cells in Mouse Renal Transplantation
1Starzl Transplantation Institute, Pittsburgh, PA, 2American University of Beirut, Beirut, Lebanon
*Purpose: The newly identified tissue resident subset of memory T cells (TRM) provides immune surveillance in the tissue and first response against infections. They are…2019 American Transplant Congress
Frailty Associated with Increased Rates of Acute Cellular Rejection within 3 Months after Liver Transplantation
*Purpose: Frailty, a state of decreased physiologic reserve and increased vulnerability to health stressors, has an inflammatory biologic basis and has been associated with dysregulation…2019 American Transplant Congress
Antibody-Suppressor CD8+ T Cells Require CXCR5
*Purpose: We previously reported the novel activity of alloprimed CD8+ T cells that suppress post-transplant alloantibody production. The purpose of the current study was to…
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