2020 American Transplant Congress
De Novo DSA in the Setting of Stable Renal Allograft Function Does Not Impair Long-Term Graft Survival
*Purpose: To determine the long-term outcome of renal allograft recipients with de novo DSA (dnDSA) in the setting of stable allograft function.*Methods: A single-center review…2020 American Transplant Congress
The Histological Picture of Indication Biopsies in the First Days after Renal Transplantation
Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
*Purpose: In preclinical studies, ischemia reperfusion injury and older donor age are associated with renal inflammation in the early phase after transplantation. In human kidney…2020 American Transplant Congress
Factors Influencing Background Cell-Free DNA Levels: Implications for Donor-Derived Cell-Free DNA Assessment in Transplant Patients
*Purpose: Detecting elevated levels of donor-derived cell-free DNA (dd-cfDNA) in the plasma of transplant recipients has been used as a metric to determine graft injury…2020 American Transplant Congress
The Impact of Thy1 Expression of Fibroblast for Chronic Lung Allograft Dysfunction
*Purpose: Chronic lung allograft dysfunction (CLAD) result from excessive immune activation and excessive collagen deposition by fibroblasts within the lung parenchyma or airway.Bronchiolitis obliterans (OB)…2020 American Transplant Congress
Stability of T Reg with Combination of mTOR Inhibitors with Belatacept in Reducing Risk of Acute Rejection in Kidney Transplant
University of California San Francisco (UCSF), San Francisco, CA
*Purpose: Belatacept is a costimulatory blocker that is used as de novo maintenance immunosuppression in kidney transplantation to avoid toxic effects of calcineurin inhibitors and…2020 American Transplant Congress
Multiplexed Imaging Mass Cytometry Analysis Reveals a New Role for CD68+ Macrophages in Chronic Liver Transplant Rejection
University of Southern California, Los Angeles, CA
*Purpose: Rejection continues to be an important cause of graft loss and failure post-liver transplant (LT). Recently, a novel high-resolution mass spectrometry-based technique has been…2020 American Transplant Congress
Apoptotic Exosome-Like Vesicles are Associated with Alloimmune Vascular Injury in Kidney Transplant Recipients
*Purpose: There is no non-invasive biomarker of alloimmune vascular injury. We have previously characterized exosome-like vesicles enriched in active proteasome and LG3 (ApoExo) that are…2020 American Transplant Congress
Unusual Case of Delayed Onset Proteinuria in AT1R Antibody Mediated Rejection
Nephrology and Hypertension, University of Louisville, Louisville, KY
*Purpose: Describing the nuances in treatment of Angiotensin receptor II Type I antibody mediated rejection*Methods: Complement-independent Angiotensin receptor II Type I antibodies (AT1R-Ab) have been…2020 American Transplant Congress
Induction Immunosuppression with Thymoglobulin May Improve Graft Outcomes without Increasing a Risk for Infection in Patients Undergoing Liver Transplantation Alone
*Purpose: Immunosuppression protocols for liver transplant (LT) vary between institutions and roles of induction immunosuppression in LT remain controversial. The aim of this study was…2020 American Transplant Congress
Single-Cell Transcriptional Profiling Reveals Cellular Diversity and Intercommunication During Cardiac Allograft Rejection in the Mouse Heart Transplantation
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: Allograft rejection is still the leading causes of the graft loss, especially long-term outcome. Single-cell genomics techniques are revolutionizing our ability to comprehensively characterize…
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