2022 American Transplant Congress
Dynamic Changes of Serum Soluble B Cell Activating Factor in Kidney Transplant with De Novo Donor Specific Antibody
*Purpose: De novo donor specific antibody (dnDSA) plays a crucial role in the development of antibody mediated rejection (ABMR) and is correlated to the worse…2022 American Transplant Congress
Acute Cellular Rejection in Liver Transplant Recipients Following Vaccination Against Covid-19
*Purpose: The coronavirus disease 2019 (COVID-19) global pandemic has seen the development of effective vaccines in record time. We report a series of five liver…2022 American Transplant Congress
Correlation of Donor-Derived Cell-Free DNA with Histology and Molecular Diagnoses of T-cell Mediated Rejection in Kidney Transplant Biopsies
1Virginia Commonwealth University, Richmond, VA, 2University of Alberta, Edmonton, AB, Canada
*Purpose: We have reported the correlation of donor-derived cell-free DNA (dd-cfDNA) with histologic and molecular diagnosis (MMDx) of kidney transplant biopsies (Gupta et al, Transplantation…2022 American Transplant Congress
Monitoring of Kidney Allograft Rejection Using Patient-Centric State-of-the-Art Tools – An Approach to Early Diagnosis and Intervention
*Purpose: The early detection and timely management of kidney allograft rejection using traditional markers including serum creatinine (SCr) has been inadequate due to lagging response.…2022 American Transplant Congress
Impact of Varying Levels of Normal Range Baseline Donor Derived Cell Free DNA on Medium-Term Outcomes Following Kidney Transplantation
*Purpose: Donor derived cell free DNA (dd-cfDNA) is a biomarker with high negative predictive value for ruling out acute rejection (AR) in kidney allografts. Baseline…2022 American Transplant Congress
Identification Of A Novel Peripheral Blood Six-gene Signature Diagnosing Subclinical Acute Rejection After Renal Transplantation
Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
*Purpose: Given the insensitivity and nonspecificity of serum creatinine, invasive surveillance biopsies are the main way to detect subclinical acute rejection (subAR) in the absence…2022 American Transplant Congress
Impact of Target Tacrolimus Levels on BK Polyomavirus DNAemia and Allograft Rejection Among Pediatric Kidney Transplant Recipients
*Purpose: BK Polyomavirus (BK) DNAemia is a serious and common infectious complication after kidney transplant (KT). We evaluated the impact of targeting lower tacrolimus levels…2022 American Transplant Congress
Concordance of Kidney and Pancreas Rejection on Protocol and for Cause Biopsy in Simultaneous Kidney Pancreas Transplantation
*Purpose: Our aim was to study the concordance rate of kidney and pancreas rejection in patients who received simultaneous kidney-pancreas transplantation (SKP) and its effects…2022 American Transplant Congress
Single Cell RNA Sequencing Identifies Primarily Terminal Effector and Exhausted CD8+T Cells in Chronically Rejected Human Kidney Allografts
*Purpose: Chronic renal allograft rejection often leads to irreversible damage, despite intensification of immunosuppression (ISN). T cell phenotypes in this clinical setting are not well…2022 American Transplant Congress
The Impact of Soluble Human Leukocyte Antigen (HLA) on Renal Antibody-Mediated Rejection (AMR) After Simultaneous Liver Kidney Transplantation (SLKT)
1Mayo Clinic, Phoenix, AZ, 2St. Joseph's Hospital and Medical Center, Phoenix, AZ
*Purpose: The lower incidence of AMR and higher incidence of rejection-free grafts survival in SLKT recipients as compared to kidney transplant recipients have been clearly…
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