ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Rejection"

  • 2015 American Transplant Congress

    The Occurrence of v- Lesions Is Not Associated With Decreased Graft Survival

    P. Halloran, I. Salazar, M. Lopez, J. Chang.

    ATAGC, Edmonton, Canada.

    Intimal arteritis (v-lesions) in kidney transplant biopsies has been believed to have major prognostic and diagnostic significance. We assessed the relationship of v-lesions to prognosis…
  • 2015 American Transplant Congress

    Glucose Chemical Exchange Saturation Transfer MRI of Acute Renal Allograft Rejection

    D. Kentrup,1 A. Busch,2 H. Pawelski,1 V. Hoerr,2,3 S. Reuter.1

    1Department of Medicine D, University Hospital Münster, Münster, Germany; 2Department of Clinical Radiology, University Hospital Münster, Münster, Germany; 3Institute of Medical Microbiology, Jena University Hospital, Jena, Germany.

    Purpose: During acute rejection episodes large amounts of immune cells infiltrate renal grafts, leading to inflammation accompanied by an increased glucose metabolism.Given these circumstances we…
  • 2015 American Transplant Congress

    De Novo Donor-Specific HLA Antibodies After Kidney Transplantation Are Associated With Donation After Circulatory Death and HLA-DQ Mismatch

    G. Dreyer,1 D. Roelen,2 S. Brand-Schaaf,2 O. Dekkers,3 M. Reinders,1 F. Claas,2 J. de Fijter.1

    1Nephrologie, LUMC, Leiden, Netherlands; 2Immunohaematology and Blood Transfusion, LUMC, Leiden, Netherlands; 3Clinical Epidemiology, Aarhus Medical Center, Aarhus C, Denmark.

    Introduction: De novo donor-specific HLA-antibodies (dnDSA) have been associated with rejection and inferior kidney graft survival. The purpose of this study was to investigate the…
  • 2015 American Transplant Congress

    Immune-Mediated Injury in Kidney Transplant Recipients Treated With Alemtuzumab Induction and a Steroid Avoidance Protocol

    R. Sapir-Pichhadze, T. Mahbub, C. Saw, D. Baran.

    McGill University Health Centre, Montreal, Canada.

    Study purpose: We evaluated short-term clinical and immunological outcomes of kidney transplant recipients who received alemtuzumab induction and a steroid-avoidance protocol.Methods: This is a retrospective…
  • 2015 American Transplant Congress

    Allograft Enterectomy as a Life-Saving Procedure and Salvage for Retransplantation

    S. Nagai, R. Mangus, B. Ekser, C. Kubal, J. Fridell, A. Tector.

    Transplant Surgery, Indiana University School of Medicine, Indianapolis, IN.

    Background: Allgraftectomy after solid organ transplantation is usually performed as a palliative therapy. After isolated intestinal transplantation (IIT), allograft enterectomy is sometimes necessary as a…
  • 2015 American Transplant Congress

    ABO Incompatible Simultaneous Liver-Kidney Transplant With Positive Crossmatch. A Case Report

    T. Heffron,1 C. Kulig,2 P. Gauthier,2 B. Bista,2 S. Dionne,3 T. Pillen,1 M. Asolati.1

    1Surgery, Porter Adventist Hospital, Denver, CO; 2Medicine, Porter Adventist Hospital, Denver, CO; 3LABS, Inc., Centennial, CO.

    INTRODUCTION: Donor Specific (DS) antibodies and ABO incompatibility remain major immunological barriers in organ transplantation. Clinical evidence suggest the liver can protect a kidney from…
  • 2015 American Transplant Congress

    Moderate Rejection Episode of Face Transplant After mTOR Conversion to Preserve Renal Function

    R. Barth,1 B. Bojovic,1 J. Woodall,1 M. Uluer,1 C. Drachenberg,1 C. Shaffer,1 N. Kelly,1 E. Rodriguez,2 S. Bartlett.1

    1University of Maryland School of Medicine, Baltimore; 2New York Medical University, New York City.

    Face and hand vascularized composite allografts (VCA) have demonstrated durable graft survivals with conventional immunosuppression but with the appearance of renal dysfunction. Management strategies that…
  • 2015 American Transplant Congress

    Evaluation of Preformed Anti-HLA Antibody of "Unknown Origin" after Kidney Transplant in a Brazilian Center

    D. Glasberg,1 D. Monteiro de Carvalho,2 T. Matuck,2 G. Fabricio-Silva,3 M. Barbosa,1 A. Borela,1 L. Christiani,1 R. Malta,1 L. Porto.3

    1Nephrology, Bonsucesso Federal Hospital, Rio de Janeiro, Brazil; 2Transplant Service, São Francisco de Assis Hospital, Rio de Janeiro, Brazil; 3Histocompatibility and Cryopreservation Laboratory, State University of Rio de Janeiro, Rio de Janeiro, Brazil.

    Background: The use of single antigen beads assay (SAFB) for the detection of anti-HLA antibodies (Abs) may reveal the presence of Abs in individuals without…
  • 2015 American Transplant Congress

    Single Center Experience of C4d Staining of Kidney Transplant Biopsies

    R. Prashar, L. Yessayan, M. Goggins, V. Karthikeyan, K. Venkat, A. Patel.

    Division of Nephrology and Transplant Institute, Henry Ford Hospital, Detroit, MI.

    Introduction: While a diffuse positivity (>50%) of C4d in kidney transplant peritubular capillaries strongly co-relates with the presence of acute or chronic antibody mediated rejection,…
  • 2015 American Transplant Congress

    Vitamin D Supplementation and Acute Rejection Following Kidney Transplantation

    T. Horwedel,1 K. Botkin,1 J. Hagopian,1 L. Bowman,1 D. Brennan.2

    1Barnes-Jewish Hospital, St. Louis, MO; 2Washington University in St. Louis, St. Louis, MO.

    Purpose: Low serum levels of vitamin D have been associated with deleterious effects post-transplantation, including increased risk of rejection. Low serum vitamin D levels are…
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