2016 American Transplant Congress
TNT009 and Its Parental Mouse Monoclonal Antibody TNT003 Target Complement Component C1s and Effectively Block Alloantibody-Induced Classical Complement Pathway Activation – The Preclinical Experience.
Introduction. Considering the key role of the classical complement pathway as a trigger of inflammation and injury in antibody-mediated rejection (ABMR), targeted classical pathway inhibition…2016 American Transplant Congress
Effect of Inflammation on Concentration of Intracellular Tacrolimus.
Background: The use of calcineurin inhibitors improved the outcome for transplant recipients. However, acute rejection (AR) and infection remained still an unsolved problem. We evaluated…2016 American Transplant Congress
Early Post-Transplant Patient, Graft Survival and Rejection Rates Under KAS.
Background: KAS, implemented on 12/4/14, resulted in changes in recipient, donor/recipient and tx characteristics that have the potential to affect post-tx outcomes.Data and Methods: We…2016 American Transplant Congress
Better Long-Term Renal Function with Lower Incidence of Acute Rejection and Lower CMV Infection in Renal Transplant Patients Treated with a Combination of Tacrolimus and Everolimus.
Surgery - Renal Transplant Unit, Università Cattolica del Sacro Cuore, Rome, Italy.
Introduction. Recent clinical trials have shown that the combination of CNIs with Everolimus (EVE) allows CNIs minimization, which may positively impact on chronic nephrotoxicity. Aim…2015 American Transplant Congress
Long Term Outcomes of Tocilizumab Therapy for DSA+ Antibody Mediated Rejection (ABMR) Resistant to IVIG + Rituxan (I+R) Treatment
Intro: Limited options are available for treatment of ABMR in highly-HLA sensitized patients (HS). Treatment options include I+R, PLEX+I+/- R, C5-inhibitor & bortezomib. Approximately 25%…2015 American Transplant Congress
The Significant Association Between the Functional Polymorphism (Rs3761548) of Foxp3 Gene and the Severity of Acute Cellular Rejection in Liver Transplantation
Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.
Aim- Acute cellular rejection (ACR) accounts for 15-25% of graft failure in living donor liver transplantation (LDLT). T regulatory cells (Treg) play an important role…2015 American Transplant Congress
CD3+CD4+ROR gamma t+ TH17 Cells Do Not Play a Critical Role in Islet Allograft Rejection
Medicine, The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA.
We have developed a “color-coded” adoptive transfer model for T cell subset identification that enables serial analysis of islet allograft infiltrating yellow induced regulatory T…2015 American Transplant Congress
Eculizumab in Prevention of Acute Antibody-Mediated Rejection in Sensitized Deceased-Donor Kidney Transplant Recipients: 1-Year Outcomes
Complement activation by preformed DSA is a major mechanism of acute antibody-mediated rejection (aAMR) in sensitized kidney transplant recipients (KTR). We previously reported interim study…2015 American Transplant Congress
Are AT1R Antibodies as Dangerous as HLA-DSAs in Renal Allografts?
Angiotensin II type 1 receptor antibodies (AT1Rab) have been associated with a significantly lower graft survival and a higher risk of acute rejection after kidney…2015 American Transplant Congress
Association of De Novo Antibody-Mediated Rejection and Increased Hospital Costs Following Kidney Transplant in Immunologically Low-Risk Patients
While antibody-mediated rejection (AMR) is likely the primary cause of kidney transplant (KTx) failure, and its treatment can be considered expensive, incremental center costs for…
- « Previous Page
- 1
- …
- 149
- 150
- 151
- 152
- 153
- …
- 172
- Next Page »