2017 American Transplant Congress
Gut Microbial Metabolite Improves Function and Prolongs Kidney Allograft Survival in Mice.
To determine the impact of dietary administration of the gut microbial metabolite sodium acetate (SA) on kidney rejection and survival in a fully MHC-mismatched murine…2017 American Transplant Congress
Urinary Proteomic Biomarkers Discovery for Prediction of Acute Rejection in Kidney Transplant Recipients.
Internal Medicine, Kyungpook National University Hospital, Daegu, Republic of Korea
Background: Early prediction and treatment of acute rejection are crucial in kidney transplant recipients (KTRs) to prevent allograft loss. Changes in the serum and urinary…2017 American Transplant Congress
Assessment of Donor-Reactive T-Cell Immunity by the Novel Urine Cell-Derived Alloantigen Assay Allows Prediction of Acute Rejection in Renal Transplant Patients.
Presensitization and donor-specific immunity play a major role in acute and chronic rejection of kidney transplant patients. While assessment of humoral sensitization is well standardised…2017 American Transplant Congress
Immune Monitoring-Guided Treatment of a Pediatric Patient with Sequential GvHD, Acute Rejection and CMV Infection Following Lung Transplantation.
Background: A 17 year old patient with cystic fibrosis (HLA-A11+, CMV-) underwent bilateral sequential lung transplantation (donor: HLA-A32+, CMV+). Immunosuppression (IS) consisted of Tacrolimus, MMF…2017 American Transplant Congress
Association of Non-HLA Antibodies with Histological Changes of Antibody Mediated Injury in Kidney Transplantation.
1Division of Nephrology, University of Washington, Seattle; 2Bloodworks NW, Seattle
Solid phase assays, particularly single-antigen beads, have substantially increased the sensitivity and accuracy of antibody detection in transplantation. However, donor specific antibodies(DSA) against human leukocyte…2017 American Transplant Congress
Donor Smoking History Associated with Increased Risk of Death Following Lung Transplantation, but Lower Risk of Bronchiolitis Obliterans Syndrome.
Cardiothoracic Surgery, University of Iowa, Iowa City, IA
Purpose: The impact of donor smoking history on long term mortality, causes of mortality and the development of bronchiolitis obliterans syndrome (BOS) following lung transplantation…2017 American Transplant Congress
CD16+ Monocytes and Skewed Macrophage Polarization Towards M2 Type Hallmark Heart Transplant Acute Cellular Rejection.
Purpose: During acute heart transplant rejection, infiltration of lymphocytes and monocytes is followed by endothelial injury and eventually myocardial fibrosis. To date, no information is…2017 American Transplant Congress
Activation of Inflammation Amplifier in Kidney Graft and Urinary Biomarker for Chronic Rejection.
[Introduction and Objective] Inflammation amplifier (IA), a local chemokine inducer in non-immune cells is induced by simultaneous activation of NFκB and STATs (IL-17, TNFα, and…2017 American Transplant Congress
Practice Patterns in the Treatment and Monitoring of Acute Cell-Mediated Kidney Graft Rejection in Canada.
Aim: to gather clinicians' views and practice patterns on the diagnosis, treatment and monitoring of acute T-cell mediated rejection (TCMR) in Canada.Methods: As part of…2017 American Transplant Congress
Treating Refractory Liver Allograft Rejection with Photopheresis.
DSAs with persistent high titer alloantibodies are associated with refractory antibody mediated rejection (AMR) and liver injury.METHODS: We present 4 liver transplant (LT) patients refractory…
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