2017 American Transplant Congress
Donor-Derived Cell-Free DNA Correlates with Antibody-Mediated Rejection in Kidney Allografts.
Purpose: Donor-derived cell-free DNA (dd-cfDNA) is a noninvasive test of allograft injury that may enable more frequent, quantitative, and safer assessment of allograft rejection and…2017 American Transplant Congress
Dysregulated Innate Immune Response Is a Robust Predictor of Allograft Injury and Survival Across All Transplanted Organs.
ObjectiveLate allograft failure is characterized by long-term cumulative effects of subclinical allograft injury. An optimal biomarker diagnoses acute rejection (AR), correlates with ongoing graft damage,…2017 American Transplant Congress
Microcirculation Inflammation in Kidney Allograft Biopsies.
Introduction: The Microcirculation Inflammation (IM) in kidney transplants is a strong predictor of graft loss inde-pedent of C4d and donor specific antibody(DSA)ObjetiveAnalysis of kidney allograft…2017 American Transplant Congress
Low Incidence of Acute Rejection within the Six Months After Transplantation in HIV Recipients Treated with Raltegravir, the ANRS 153 Treve Trial.
Renal transplantation is safe and effective in HIV patients with end stage renal disease (ESRD). High rates of acute rejection (AR) have been reported because…2017 American Transplant Congress
Second-Line Therapy After Standard of Care in Antibody-Mediated Rejection: A Prospective Study.
Paris Translational Research Center for Organ Transplantation, Paris, France
There is a marked heterogeneity in AMR patients' prognosis after SOC treatment including plasma exchange (PE) and intravenous immunoglobulins (IVIG). We investigated whether a composite…2017 American Transplant Congress
Significance of Thrombotic Microangiopathy in Renal Allografts.
Thrombotic microangiopathy (TMA) in the renal allograft is a form of renal capillary injury that may associate with many disorders including calcineurin inhibitor (CI) toxicity,…2017 American Transplant Congress
Improved Mouse Renal Transplantation Model Simulating Clinical Antibody Mediated Rejection.
Background: Acute antibody mediated rejection (AMR) is main barrier to long term renal graft survival. Mouse model is important to understand the mechenisms of AMR.…2017 American Transplant Congress
Is There a Role for Electronic Health Service in of Therapeutic Drug Monitoring of Immunosuppression?
Background: Therapeutic drug monitoring (TDM) of immunosuppression is critical to avoid rejection or toxic side effects by under- or over-immunosuppression after heart transplantation (HTx). Hence,…2017 American Transplant Congress
Clinical Impact of Strength and Class of Pre transplant Donor Specific Antibody on Kidney Transplant Recipient Receiving Steroid Free Maintenance Immunosupression Regimen.
Renal Transplant, Indiana University School of Medicine, Indianapolis, IN
Background: The class and strength of pre- transplant DSA has been described as playing a role in determining future risk of acute rejection (AR) and…2017 American Transplant Congress
Isolated Angiotensin II Receptor Type I Antibodies (AT1R) Are Not Associated with Active Antibody Mediated Rejection (ABMR) in Pediatric Renal Transplant Recipients.
Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA
Intro: Donor specific antibodies (DSAs) detected post transplant are associated with ABMR and graft dysfunction. The role of non-HLA antibodies especially angiotensin II receptor type…
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