2017 American Transplant Congress
Incidence of Donor-Specific Anti-HLA Antibodies in Non-HLA Sensitized Patients Given Tacrolimus Once or Twice Daily During the First Two Years Post-Transplantation.
Department of Nephrology and Organ Transplantation, Toulouse University Hospital, Toulouse, France
Donor-specific anti-HLA antibody (DSA)-mediated rejection (AMR) is a main cause of graft loss after kidney transplantation. Non-adherence is a risk factor for AMR and graft…2017 American Transplant Congress
Preservation of Musculoskeletal Components in Vascularized Composite Allograft Skin Rejection.
University of Maryland School of Medicine, Baltimore, MD
Background: Severe or chronic rejection of vascularized composite allografts (VCA) has resulted in graft loss and patient deaths. 'Split tolerance' has been defined in patterns…2017 American Transplant Congress
Death After Kidney Transplantation: Assessment of Pre- and Peri-Transplant Risk Factors and of Time-Varying Risk Factors from the Post-Transplant Course.
Deaths over a period of up to 10 years post-transplantation (Tx) and the associated risk factors were examined in patients (pts) with protocol biopsies (total…2017 American Transplant Congress
CXCL13 as a New Systemic Biomarker for B-Cell Involvement in Acute Kidney Allograft Rejection.
The majority of kidney allograft rejections are T cell mediated (TCMR). However, it has been shown that in the presence of B-cell clusters the course…2017 American Transplant Congress
Persistence/Progression of Early Banff Borderline Changes (BBC) Is Associated with Chronic Renal Allograft Damage and Can Be Predicted by B Cell Cytokine Profile.
The clinical significance of early histological BBC in kidney transplant recipients (KTR) is unclear. It is also unknown if biomarkers predict progression to acute rejection…2017 American Transplant Congress
Impact of Antihypertensive (AHT) Choice and Advagraf® Dose on Immunologic Events in Renal Allografts 24 Months Post-Transplantation (Tx).
Renal allograft inflammation may be modulated by ACEi- or ARB-type AHTs (renin-angiotensin system (RAS)-targeting drugs that may inhibit calcineurin) or by optimizing tacrolimus (TAC) exposure.…2017 American Transplant Congress
Tacrolimus Trough Concentration Variability and Disparities in African American Kidney Transplantation.
Low tacrolimus (FK) trough concentrations have been associated with higher risk of acute rejection, particularly within African-American (AA) kidney transplant recipients; less is known about…2017 American Transplant Congress
Differential Expression of Long Noncoding RNAs During Cardiac Allograft Rejection.
While transplant rejection is the major restriction in successful long lasting graft survival, induction of sustainable immune tolerance against transplant is one of the major…2017 American Transplant Congress
Neutropenia in Kidney Transplantation: A Hidden Threat to Graft Survival.
Medstar Georgetown Transplant Institute, Washington, DC
IntroductionNeutropenia is a common complication after kidney transplantation resulting in a reduction of immunosuppression and the use of granulocyte colony-stimulating factors (G-CSF) which can increase…2017 American Transplant Congress
Not All Cellular Rejections Are the Same: Differences in Early and Late Hepatic Allograft Rejection.
While acute cellular rejection (ACR) after liver transplantation (LT) is not thought to cause long-term graft injury and inferior outcomes, this notion has been challenged…
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