2017 American Transplant Congress
Association of Non-HLA Antibodies with Histological Changes of Antibody Mediated Injury in Kidney Transplantation.
1Division of Nephrology, University of Washington, Seattle; 2Bloodworks NW, Seattle
Solid phase assays, particularly single-antigen beads, have substantially increased the sensitivity and accuracy of antibody detection in transplantation. However, donor specific antibodies(DSA) against human leukocyte…2017 American Transplant Congress
Donor Smoking History Associated with Increased Risk of Death Following Lung Transplantation, but Lower Risk of Bronchiolitis Obliterans Syndrome.
Cardiothoracic Surgery, University of Iowa, Iowa City, IA
Purpose: The impact of donor smoking history on long term mortality, causes of mortality and the development of bronchiolitis obliterans syndrome (BOS) following lung transplantation…2017 American Transplant Congress
CD16+ Monocytes and Skewed Macrophage Polarization Towards M2 Type Hallmark Heart Transplant Acute Cellular Rejection.
Purpose: During acute heart transplant rejection, infiltration of lymphocytes and monocytes is followed by endothelial injury and eventually myocardial fibrosis. To date, no information is…2017 American Transplant Congress
Activation of Inflammation Amplifier in Kidney Graft and Urinary Biomarker for Chronic Rejection.
[Introduction and Objective] Inflammation amplifier (IA), a local chemokine inducer in non-immune cells is induced by simultaneous activation of NFκB and STATs (IL-17, TNFα, and…2017 American Transplant Congress
Practice Patterns in the Treatment and Monitoring of Acute Cell-Mediated Kidney Graft Rejection in Canada.
Aim: to gather clinicians' views and practice patterns on the diagnosis, treatment and monitoring of acute T-cell mediated rejection (TCMR) in Canada.Methods: As part of…2017 American Transplant Congress
Treating Refractory Liver Allograft Rejection with Photopheresis.
DSAs with persistent high titer alloantibodies are associated with refractory antibody mediated rejection (AMR) and liver injury.METHODS: We present 4 liver transplant (LT) patients refractory…2017 American Transplant Congress
Tacrolimus Appears to Be a Protective Factor for De Novo DSA Formation in Non-Sensitized Kidney Transplant Patients.
Background.Development of de novo donor specific antibodies (dnDSA) concerns about 10% of patients within the first year following kidney transplantation and reach about 20% within…2017 American Transplant Congress
Preceeding the Rejection: Clinical Results of a Saliva Test After Renal Transplantation.
Introduction There remains a need for biomarker in transplantation for monitoring and early identification of rejection episodes (R). We developed a colorimetric assay to detect…2017 American Transplant Congress
Early Acute Cellular Rejection(eACR) as a Marker of Immunologic Competency Following Liver Transplantation(LT).
University of Minnesota, Minneapolis, MN
Background:Historically eACR did not adversely impact patient survival(PS). Since infection(Ifx) is major cause of death(COD) among LT recipients, we hypothesized that eACR is marker of…2017 American Transplant Congress
HLA-DR Based Murine Transplant Model for Studying Collagen Type V Autoimmunity in Chronic Allograft Rejection.
Dept. of Surgery/Transplant Division, UW Madison, Madison, WI
Background: In lung and heart transplant patients, chronic rejection manifests as fibro-obliteration of airways and vessels resulting in bronchiolitis obliterans syndrome (BOS) or cardiac allograft…
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