ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Recurrence"

  • 2017 American Transplant Congress

    Maribavir for Treatment of Cytomegalovirus Infections Resistant or Refractory to Ganciclovir or Foscarnet in Solid Organ Transplant Recipients: A Phase 2 Study.

    M. Pereira,1 F. Silveira,2 G. Papanicolaou,3 A. Langston,4 R. Avery,5 A. Wijatyk,6 J. Wu,6 M. Boeckh,7 F. Marty,8 S. Villano.9

    1Columbia University Medical Center, New York, NY; 2University of Pittsburgh Medical Center, Pittsburgh, PA; 3Memorial Sloan Kettering Cancer Center, New York, NY; 4Winship Cancer Institute, Atlanta, GA; 5Johns Hopkins University, Baltimore, MD; 6Shire, Lexington, MA; 7Fred Hutchinson Cancer Research Center, Seattle, WA; 8Brigham and Women's Hospital, Boston, MA; 9Shire (At Time of Study), Wayne, PA

    Study NCT01611974 assessed safety, tolerability, and antiviral activity of maribavir (MBV) for treatment of resistant or refractory (R/R) CMV infections among transplant recipients. Those aged…
  • 2017 American Transplant Congress

    Eculizumab Dose Reduction Is Safe by Monitoring Eculizumab Pre-Dose Level and Functional Complement Assays.

    M. Gelens,1 T. Havenith,2 J. Damoiseaux,3 M. Christiaans.1

    1Internal Medicine, MUMC, Maastricht, Netherlands; 2Clinical Pharmacy, MUMC, Maastricht, Netherlands; 3Central Diagnostic Laboratory, MUMC, Maastricht, Netherlands

    Background & aims: Untreated atypical haemolytic syndrome (aHUS) leads to ESRD and may recur after renal transplantation. Eculizumab (Ecu), a humanized antibody inhibiting terminal C5…
  • 2017 American Transplant Congress

    Prognostic Significance of Preoperative Neutrophil-Lymphocyte Ratio in Patients Undergoing Liver Transplantation with Hepatocellular Carcinoma within Milan Criteria.

    S.-K. Kwon,1 J. Lee,1 S. Song,1 J. Lee,1 D. Kim,1 J. Lee,2 M. Kim,1 G. Choi,1 J. Choi,1 D. Han,1 S. Kim,1 D. Joo.1

    1Department of Surgery, Yonsei University College of Medicine, Seoul, Korea; 2Department of Surgery, CHA University, Bundang, Korea

    Introduction: The systemic inflammation biomarker, neutrophil-to-lymphocyte ratio (NLR) has been reported to be a predioctor of poor survival in patients with various cancers. The purpose…
  • 2017 American Transplant Congress

    Novel Insights into the Synergism of CD40 Autoantibodies and suPAR in Kidney Transplant Patients with FSGS Recurrence.

    T. Sigdel, C. Wei, F. Vencenti, J. Reiser, M. Sarwal.

    University of California San Francisco, San Francisco

    Background: FSGS is a histopathological lesion that has a 40-80% risk of recurrence o in the transplanted (tx) kidney, with increased risk of graft loss.…
  • 2017 American Transplant Congress

    Different Prognostic Factors for Early and Late Recurrence After Adult Living Donor Liver Transplantation for Hepatocellular Carcinoma.

    S. Hong, K.-W. Lee, H.-S. Kim, S.-W. Ahn, K. Yoon, H. Kim, N.-J. Yi, K.-S. Suh.

    Surgery, College of Medicine, Seoul National University, Seoul, Republic of Korea

    Recurrence after liver transplantation (LT) for hepatocellular carcinoma (HCC) remains unsatisfactory. However, some patients with HCC recurrence after LT show good long-term survival results. The…
  • 2017 American Transplant Congress

    Transcriptome Analysis of CD4-Lymphocyte Specifically Deleted of IKKbeta or NEMO in an Experimental Model of Rapid Progressive Glomerulonephritis (RPGN).

    F. Thaiss,1 J. Huang,2 M. Chen,1 H. Paust,1 G. Zahner,1 M. Alawi,2 R. Geffers,3 L. Guo.1

    1Nephrology, Univ. Hospital UKE, Hamburg, Germany; 2Bioinformatics, Univ. Hospital UKE, Hamburg, Germany; 3Genomics, Helmholtz Center Infection, Braunschweig, Germany

    RPGN is T-cell mediated and can recur after kidney transplantation. T-cell receptor stimulation leads to intracellular signaling events ultimately causing activation of transcription factors such…
  • 2017 American Transplant Congress

    Which Way to Go, Liver Resection or Liver Transplantation for Hepatocellular Carcinoma in Child A Liver Cirrhosis.

    K. Yoon, K.-W. Lee, H. Kim, D. Oh, H.-S. Kim, S. Ahn, S. Hong, N.-J. Yi, K.-S. Suh.

    Department of Surgery, Seoul National University College of Medicine, Seoul, Jongrogu, Republic of Korea

    Introduction: Hepatocellular carcinoma(HCC) has high recurrence rate after liver resection(LR). The recurrence within Milan after LR is only 61- 79% in patient with child A.…
  • 2017 American Transplant Congress

    Anti-CD25mAb Sparing Immunosuppressive Regimen Suppressed Recurrence of Post-Transplant Focal Segmental Glomerular Sclerosis- A Single Center Experience.

    H. Harada, Y. Wada, N. Fukuzawa.

    Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan

    INTRODUCTION: The rate of recurrence of primary focal segmental glomerular sclerosis (FSGS) is problematic, because it often results in very early serious urinary protein secretion…
  • 2017 American Transplant Congress

    Predicting Recurrence Prior to Transplant: The Response of HCC to Chemoembolization.

    T. Sandow,1 H. Bohorquez,2 D. Kirsch,1 P. Thevenot,3 K. Nunez,3 A. Albar,1 D. DeVun,1 J. Gimenez,1 G. Galliano,4 A. Cohen,2 G. Loss,2 D. Kay,1 P. Gulotta.1

    1Radiology, Ochsner Clinic Foundation, New Orleans, LA; 2Transplant Surgery, Ochsner Clinic Foundation, New Orleans, LA; 3Institute of Translational Research, Ochsner Clinic Foundation, New Orleans, LA; 4Pathology, Ochsner Clinic Foundation, New Orleans, LA

    Purpose:This study assesses imaging response characteristics of patients with hepatocellular carcinoma (HCC) to chemoembolization (TACE) as a bridge to transplant and the risk of post-transplant…
  • 2017 American Transplant Congress

    Steroid-Free Immunosuppression After Liver Transplant for Autoimmune Disease Does Not Result in Increased Disease Recurrence.

    A. Hooper,1 C. Frenette.2

    1Internal Medicine, Scripps Mercy Hospital, San Diego, CA; 2Organ Transplant, Scripps Green Hospital, La Jolla, CA

    Immunosuppression regimens in patients with end stage liver disease (ESLD) from autoimmune hepatitis (AIH), primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) typically include…
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