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American Transplant Congress abstracts

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Articles tagged "Protocol biopsy"

  • 2018 American Transplant Congress

    Subclinical Borderline Rejection: More Than Meets the Eye?

    M. Bernard, G. Agarwal, H. Fatima, B. Julian, C. Kew, V. Kumar, S. Mehta, S. Ong, A. Patel, G. Towns, M. Seifert, R. Mannon.

    UAB School of Medicine, Birmingham.

    Purpose: Surveillance biopsies can detect subclinical T cell mediated rejection (SC-TCMR) or subclinical borderline rejection (SC-B-TCMR) in patients with normal/stable creatinine, but the impact on…
  • 2017 American Transplant Congress

    Infusion of Polyclonal Tregs Modulates Subclinical Kidney Transplant Inflammation: Final Report of TASK Pilot Trial.

    S. Chandran, Q. Tang, M. Sarwal, Z. Laszik, A. Putnam, T. Sigdel, E. Tavares, J. Bluestone, F. Vincenti.

    UCSF, San Francisco

    Purpose:Treg therapy can reverse established inflammation in animal models. We conducted a pilot safety & feasibility trial of Treg therapy for subclinical kidney transplant inflammation.Methods:Peripheral…
  • 2017 American Transplant Congress

    Podocyte-Specific Knockdown of SHROOM3 Causes Albuminuria and Foot-Process Effacement by Interaction with FYN.

    M. Menon, N. Philippe, C. Wei, W. Zhang, J. He, B. Murphy.

    Nephrology, Medicine, Icahn School of Medicine, New York, NY

    In the translational GoCAR study, we identified that a CKD-associated SHROOM3-SNP, and tubular SHROOM3 expression correlated with the development of renal fibrosis post-transplant. The SNP…
  • 2017 American Transplant Congress

    Quantitative Analysis of 10-Year Surveillance Renal Allograft Biopsies.

    A. Denic, B. Smith, W. Park, A. Rule, L. Cornell, M. Stegall.

    Mayo Clinic, Rochester

    Introduction. Assessing late histologic changes in renal allografts is important to investigating etiology and devising treatment. Compared to the usual semi-quantitative reading by a renal…
  • 2017 American Transplant Congress

    C3d-Binding Anti-DQ DSA Is Associated with a High Risk for Late ABMR and Graft Failure in Stable Kidney Transplant Recipients.

    D. Lee,1 B. Kim,2 J. Kim,3 I. Kim,4 M. Chun.5

    1Medicine, Maryknoll Medical Center, Busan, Republic of Korea; 2Laboratyory Medicine, Maryknoll Medical Center, Busan, Republic of Korea; 3Surgery, Maryknoll Medical Center, Busan, Republic of Korea; 4Urology, Maryknoll Medical Center, Busan, Republic of Korea; 5Pathology, Maryknoll Medical Center, Busan, Republic of Korea

    Introduction:Donor specific anti-HLA antibodies (DSA) are a major cause of antibody-mediated rejection (ABMR) and poor graft outcome in kidney transplant recipients (KTR). Critical issue is…
  • 2017 American Transplant Congress

    The Impact of Marginal Factors on the Postoperative Kidney Function of Complex Living Donors for Kidney Transplantation.

    T. Hiramitsu, K. Futamura, M. Okada, M. Tsujita, N. Goto, S. Narumi, Y. Watarai.

    Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan

    BackgroundMedically complex living donors with marginal factors are increasing.MethodsBetween January 2008 and May 2015, 639 living donors for kidney transplantation were included. Marginal factors for…
  • 2017 American Transplant Congress

    Short Term Renal Allograft Outcomes Following Treatment of Early Subclinical Borderline Changes on Surveillance Biopsies.

    C. James, K. Woodside, J. Park, A. Naik, E. Farkash, R. Sung, M. Samaniego, Y. Huang.

    University of Michigan, Ann Arbor, MI

    There is no consensus on treating subclinical borderline changes on surveillance biopsy in kidney transplant (KT) recipients. We examined whether treatment with pulsed corticosteroids led…
  • 2017 American Transplant Congress

    The Value of Protocol Biopsy at Third Month After Kidney Transplant: A Single-Center Cohort Analysis.

    R. Rosado-Canto, C. Barrientos-Aguilar, I. Parra-Avila, L. Marino, M. Arvizu-Hernandez, N. Uribe-Uribe, L. Morales-Buenrostro.

    Departament of Nephrology and Transplant, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico

    Introduction: In spite of publications reporting higher detection of subclinical rejection (SR) with protocol biopsies in kidney transplant (KT) recipients there is no recommendation with…
  • 2017 American Transplant Congress

    Death After Kidney Transplantation: Assessment of Pre- and Peri-Transplant Risk Factors and of Time-Varying Risk Factors from the Post-Transplant Course.

    I. Scheffner,1 T. Abeling,1 A. Karch,1 M. Mengel,2 V. Broeker,3 A. Koch,1 H. Haller,1 A. Schwarz,1 W. Gwinner.1

    1Hannover Medical School, Hannover, Germany; 2Alberta Transplant Applied Genomics Centre, Edmonton, Canada; 3University of Gothenburg, Gothenburg, Sweden

    Deaths over a period of up to 10 years post-transplantation (Tx) and the associated risk factors were examined in patients (pts) with protocol biopsies (total…
  • 2017 American Transplant Congress

    Scoring of Distinct Tubular Injury Features and Assessment of Cellular Proliferation and of Non-Apoptotic Cell Death by the Novel Marker FACL4 Allow to Determine the Long-Term Prognosis of Renal Grafts.

    A. Bohlmann,1 J. Schmitz,1 A. Melk,1 R. Schmitt,1 I. Scheffner,1 V. Broeker,2 H. Haller,1 J. Metzger,3 J. Braesen,1 W. Gwinner.1

    1Hannover Medical School, Hannover, Germany; 2University of Gothenburg, Gothenburg, Sweden; 3Mosaiques Diagnostics, Hannover, Germany

    Acute tubular injury (ATI) is common in renal grafts and is related to an inferior long-term function. There is no consensus which of the tubular…
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