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Articles tagged "Prophylaxis"

  • 2020 American Transplant Congress

    Letermovir for CMV Prophylaxis and Treatment of Resistant/ Refractory CMV Disease in Solid Organ Transplant Recipients

    M. Miller1, S. Scherger2, E. Benamu2, V. Bajrovic2, P. Ramanan2, N. Madinger2, M. Barron2, S. Johnson2, T. Campbell2, A. Gray3, A. Weinberg4, M. Abidi2

    1Clinical Pharmacy, University of Colorado Hospital, Aurora, CO, 2Infectious Diseases, University of Colorado Denver School of Medicine, Aurora, CO, 3Pulmonology, University of Colorado Denver School of Medicine, Aurora, CO, 4Pediatrics, University of Colorado Denver School of Medicine, Aurora, CO

    *Purpose: Letermovir (LMV) is approved for primary cytomegalovirus (CMV) prophylaxis in hematopoietic cell transplant recipients. Current FDA-approved antiviral options are limited to foscarnet and cidofovir…
  • 2020 American Transplant Congress

    Early versus Delayed Initiation of CMV Prophylaxis after Liver Transplantation

    M. Magid, J. Byrns, J. Gommer, Z. Yang, M. Harris

    Duke University Hospital, Durham, NC

    *Purpose: To determine the incidence of CMV DNAemia in early (prior to post-op day 7) versus delayed prophylaxis in liver transplant recipients.*Methods: Retrospective, single-center study…
  • 2020 American Transplant Congress

    Evaluation of an Intervention to Reduce Underdosing of Valganciclovir for Primary Prophylaxis of Cytomegalovirus Infection in Donor Seropositive/Recipient Seronegative Kidney and Liver Transplant Recipients

    L. Al Bizri1, Z. S. Chaudhry2, A. Vahia2, J. Williams2, J. C. Lemos-Ramirez3, B. Summers4, A. Patel5, S. Nagai6, O. Abreu Lanfranco2, M. Ramesh2, R. Del Busto2, G. Alangaden2

    1Internal Medicine, Henry Ford Health System, Detroit, MI, 2Infectious Disease, Henry Ford Health System, Detroit, MI, 3Department of Transplant Infectious Disease, Memorial Regional Hospital, Hollywood, FL, 4Central Pharmacy, Henry Ford Health System, Detroit, MI, 5Nephrology, Henry Ford Health System, Detroit, MI, 6Surgery Transplant, Henry Ford Health System, Detroit, MI

    *Purpose: Valganciclovir (VCV) prophylaxis is used to prevent primary cytomegalovirus (CMV) infection in CMV donor seropositive/recipient seronegative (D+/R-) solid organ transplant recipients (SOT). We examined…
  • 2020 American Transplant Congress

    Twice Weekly Valganciclovir for Cytomegalovirus Infection Prophylaxis in Kidney Transplant Recipients with Delayed Graft Function on Hemodialysis

    S. A. Mehta1, A. Katz2, R. Dieter2, P. Jen2, J. Siegfried2, J. Papadopoulos2, T. Lewis2

    1Infectious Diseases, NYU Langone Health, New York, NY, 2Pharmacy, NYU Langone Health, New York, NY

    *Purpose: The incidence of cytomegalovirus (CMV) remains high in the first year following kidney transplantation. Valganciclovir (VGC) is commonly prescribed in the early post-operative period…
  • 2020 American Transplant Congress

    Incidence of Oropharyngeal and Esophageal Candidiasis in Adult Kidney Transplant Recipients Receiving Nystatin versus No Prophylaxis

    L. Moreno1, K. Klein1, C. Long2, R. Hall1, J. Nelson1

    1Pharmacotherapy and Pharmacy Services, Pharmacotherapy Division, University Health System, The University of Texas Health Science Center at San Antonio, The University of Texas at Austin, College of Pharmacy, San Antonio, TX, 2Pharmacotherapy and Pharmacy Services, Pharmacy Practice, University Health System, University of the Incarnate Word Feik School of Pharmacy, San Antonio, TX

    *Purpose: The purpose of this study is to evaluate the need for nystatin prophylaxis for oropharyngeal (OPC) and esophageal Candidiasis (EC) in adult kidney transplant…
  • 2020 American Transplant Congress

    Epidemiology of Invasive Fungal Infections in Heart Transplant Recipients

    A. Couture-Cossette1, A. Puing1, A. Multani2, O. Quintero1, A. K. Subramanian1, E. Henricksen3, R. Lee1, Y. Moayedi4, K. Khush5, J. J. Teuteberg5, D. Y. Ho1

    1Department of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA, 2Department of Infectious Diseases, UCLA, Stanford, CA, 3Pharmacy, Stanford Healthtcare, Stanford, CA, 4Department of Cardiology, UHN, Toronto, ON, Canada, 5Division of Cardiology, Department of Medicine, Stanford University, Stanford, CA

    *Purpose: The incidence and epidemiology of invasive fungal infections (IFI) after heart transplantation (HTx) are influenced by changes in environmental exposures, immunosuppression, and prophylaxis practices.…
  • 2020 American Transplant Congress

    Does Antibiotic Prophylaxis at Ureteral Stent Removal Reduce Urinary Tract Infections in Kidney Transplant Recipients?

    M. Tarokh1, B. Frainey2, M. Fascelli3, D. Goldfarb1, A. Wee3, M. Eltemamy3

    1Kidney Transplant Surgery, Cleveland Clinic, Cleveland, OH, 2Glickman Urological and Kidney Institute, Urology, Cleveland Clinic, Cleveland, OH, 3Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH

    *Purpose: Ureteral stents are commonly placed during kidney transplantation (KT). Urinary tract infections (UTI) are a common risk factor after KT and can have detrimental…
  • 2020 American Transplant Congress

    Efficacy and Safety According to Dose of Valganciclovir for Cytomegalovirus Prophylaxis in Transplantation Network Meta Analysis

    S. Hwang, W. Park, K. Kim, J. Song, S. Lee

    Inha University, Incheon, Korea, Republic of

    *Purpose: Valgancivlovir is importantly used to prevent post-transplant CMV infection among kidney transplantation patients. However, the dose of such drug being used still remains controversial…
  • 2020 American Transplant Congress

    Efficacy of Single-Strength Trimethoprim-Sulfamethoxazole Thrice Weekly for Pneumocysitis Jirovecii Pneumonia Prophylaxis Post Liver Transplantation

    A. Puing, A. Subramanian

    Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA

    *Purpose: Current guidelines recommend Pneumocystis jirovecii pneumonia (PJP) prophylaxis for at least 6-12 months after liver transplant (LTx) with preferably Trimethoprim-sulfamethoxazole (TMP-SMX) at a daily…
  • 2020 American Transplant Congress

    Once Weekly Fluconazole is Effective for the Prevention of Oral Candidiasis in Kidney Transplant Recipients

    J. Lockridge, D. Roberts, K. Spence, M. Stack, S. Rehman, A. Olyaei

    OHSU, Portland, OR

    *Purpose: Oropharyngeal candidiasis is an infection prevalent in renal transplant recipients, with significant concerns for invasive endoscopic workup and development into invasive fungal infections. While…
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