Articles tagged "Prophylaxis"

2020 American Transplant Congress
Antimicrobial Prophylaxis Post Antibody Mediated Rejection Treatment in Pediatric Kidney Transplant Recipients: Interim Report from the Paramour “PediAtric Renal AMr Outcomes” Study
S. Solomon¹, R. Garro², N. Hayde³, A. Jain⁴, M. Kallash⁵, K. Twombley⁶, I. Ashoor⁷
¹Maria Fareri Children's Hospital, Valhalla, NY, ²Emory University, Atlanta, GA, ³The Children's Hospital at Montefiore, Bronx, NY, ⁴Children's Hospital of Michigan, Detroit, MI, ⁵Nationwide Children's Hospital, Columbus, OH, ⁶Medical University of South Carolina, Charleston, SC, ⁷LSU Health New Orleans, New Orleans, LA
*Purpose: Universal guidelines do not exist for post antibody mediated rejection (AMR) treatment antimicrobial prophylaxis (ppx) in pediatric kidney transplant (KT) recipients. We sought to…
2020 American Transplant Congress
Stewardship Effortsto Eliminate Post-Orthotopic Liver Transplant Antibiotics in Uncomplicated Patients Leads to Equivalent Safety Outcomes
J. Yau, J. Dann, W. Ally, J. Geyston, S. Pelletier, C. Sifri
University of Virginia Health System, Charlottesville, VA
*Purpose: The purpose of this study was to evaluate safety and efficacy endpoints of a revised post-operative antibiotic prophylaxis protocol in orthotopic liver transplant (OLT)…
2020 American Transplant Congress
Pneumocystis Pneumonia Occurrence and Prophylaxis Duration in Kidney Transplant Recipients According to Perioperative Treatment with Rituximab
Y. Ko, Y. Kim, D. Han, H. Kwon
Department of Surgery, Division of Kidney and Pancreas Transplant, AMC, Seoul, Korea, Republic of
*Purpose: Pneumocystis pneumonia (PCP) is a life-threatening fungal infection that can occur in kidney transplantation (KT) recipients. A growing number of KT recipients are receiving…
2020 American Transplant Congress
Role of Tacrolimus Dose Adjustment at Discontinuation of Fluconazole in Liver Transplant
J. Yau, H. Morris
University of Virginia Health System, Charlottesville, VA
*Purpose: The purpose of this study was to characterize the effects of fluconazole (fluc) discontinuation on tacrolimus (tac) levels and the role of prophylactic dose…
2020 American Transplant Congress
Letermovir for CMV Prophylaxis and Treatment of Resistant/ Refractory CMV Disease in Solid Organ Transplant Recipients
M. Miller¹, S. Scherger², E. Benamu², V. Bajrovic², P. Ramanan², N. Madinger², M. Barron², S. Johnson², T. Campbell², A. Gray³, A. Weinberg⁴, M. Abidi²
¹Clinical Pharmacy, University of Colorado Hospital, Aurora, CO, ²Infectious Diseases, University of Colorado Denver School of Medicine, Aurora, CO, ³Pulmonology, University of Colorado Denver School of Medicine, Aurora, CO, ⁴Pediatrics, University of Colorado Denver School of Medicine, Aurora, CO
*Purpose: Letermovir (LMV) is approved for primary cytomegalovirus (CMV) prophylaxis in hematopoietic cell transplant recipients. Current FDA-approved antiviral options are limited to foscarnet and cidofovir…
2020 American Transplant Congress
Early versus Delayed Initiation of CMV Prophylaxis after Liver Transplantation
M. Magid, J. Byrns, J. Gommer, Z. Yang, M. Harris
Duke University Hospital, Durham, NC
*Purpose: To determine the incidence of CMV DNAemia in early (prior to post-op day 7) versus delayed prophylaxis in liver transplant recipients.*Methods: Retrospective, single-center study…
2020 American Transplant Congress
Evaluation of an Intervention to Reduce Underdosing of Valganciclovir for Primary Prophylaxis of Cytomegalovirus Infection in Donor Seropositive/Recipient Seronegative Kidney and Liver Transplant Recipients
L. Al Bizri¹, Z. S. Chaudhry², A. Vahia², J. Williams², J. C. Lemos-Ramirez³, B. Summers⁴, A. Patel⁵, S. Nagai⁶, O. Abreu Lanfranco², M. Ramesh², R. Del Busto², G. Alangaden²
¹Internal Medicine, Henry Ford Health System, Detroit, MI, ²Infectious Disease, Henry Ford Health System, Detroit, MI, ³Department of Transplant Infectious Disease, Memorial Regional Hospital, Hollywood, FL, ⁴Central Pharmacy, Henry Ford Health System, Detroit, MI, ⁵Nephrology, Henry Ford Health System, Detroit, MI, ⁶Surgery Transplant, Henry Ford Health System, Detroit, MI
*Purpose: Valganciclovir (VCV) prophylaxis is used to prevent primary cytomegalovirus (CMV) infection in CMV donor seropositive/recipient seronegative (D+/R-) solid organ transplant recipients (SOT). We examined…
2020 American Transplant Congress
Twice Weekly Valganciclovir for Cytomegalovirus Infection Prophylaxis in Kidney Transplant Recipients with Delayed Graft Function on Hemodialysis
S. A. Mehta¹, A. Katz², R. Dieter², P. Jen², J. Siegfried², J. Papadopoulos², T. Lewis²
¹Infectious Diseases, NYU Langone Health, New York, NY, ²Pharmacy, NYU Langone Health, New York, NY
*Purpose: The incidence of cytomegalovirus (CMV) remains high in the first year following kidney transplantation. Valganciclovir (VGC) is commonly prescribed in the early post-operative period…
2020 American Transplant Congress
Incidence of Oropharyngeal and Esophageal Candidiasis in Adult Kidney Transplant Recipients Receiving Nystatin versus No Prophylaxis
L. Moreno¹, K. Klein¹, C. Long², R. Hall¹, J. Nelson¹
¹Pharmacotherapy and Pharmacy Services, Pharmacotherapy Division, University Health System, The University of Texas Health Science Center at San Antonio, The University of Texas at Austin, College of Pharmacy, San Antonio, TX, ²Pharmacotherapy and Pharmacy Services, Pharmacy Practice, University Health System, University of the Incarnate Word Feik School of Pharmacy, San Antonio, TX
*Purpose: The purpose of this study is to evaluate the need for nystatin prophylaxis for oropharyngeal (OPC) and esophageal Candidiasis (EC) in adult kidney transplant…
2020 American Transplant Congress
Epidemiology of Invasive Fungal Infections in Heart Transplant Recipients
A. Couture-Cossette¹, A. Puing¹, A. Multani², O. Quintero¹, A. K. Subramanian¹, E. Henricksen³, R. Lee¹, Y. Moayedi⁴, K. Khush⁵, J. J. Teuteberg⁵, D. Y. Ho¹
¹Department of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA, ²Department of Infectious Diseases, UCLA, Stanford, CA, ³Pharmacy, Stanford Healthtcare, Stanford, CA, ⁴Department of Cardiology, UHN, Toronto, ON, Canada, ⁵Division of Cardiology, Department of Medicine, Stanford University, Stanford, CA
*Purpose: The incidence and epidemiology of invasive fungal infections (IFI) after heart transplantation (HTx) are influenced by changes in environmental exposures, immunosuppression, and prophylaxis practices.…

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