Articles tagged "Pregnancy"

2018 American Transplant Congress
Long-Term Social Outcome after Pediatric Kidney Transplantation
Y. Hamasaki,¹ T. Matsuda,¹ M. Kubota,¹ J. Hashimoto,¹ Y. Takahashi,¹ M. Muramatsu,² T. Kawamura,³ K. Sakai,² S. Shishido.^1,2
¹Pediatric Nephrology, Toho University Faculty of Medicine, Tokyo, Japan; ²Nephrology, Toho University Faculty of Medicine, Tokyo, Japan; ³Nephrology, Sakura Medical Center, Toho University, Sakura, Japan.
BackgroundPatients' and graft survival rates after pediatric kidney transplantation (KTx) were recently improved because of progress in immunosuppressants, perioperative care, and operative procedures. Therefore the…
2018 American Transplant Congress
Demand for Uterine Transplantation in the United States: Initial Recruitment Results of a Trial of Uterine Transplantation in the Northeast U.S.
P. Porrett,¹ N. Latif,² E. Wang,² L. Sortor,³ S. Levin,⁴ A. Shaked,¹ K. Olthoff,¹ C. Coutifaris,² D. Driscoll,² K. O'Neill.²
¹Surgery, University of Pennsylvania, Philadelphia, PA; ²OB/Gyn, University of Pennsylvania, Philadelphia, PA; ³Psychiatry, University of Pennsylvania, Philadelphia, PA; ⁴Orthopedic Surgery, University of Pennsylvania, Philadelphia, PA.
Background Uterine factor infertility (UFI) may affect 7 million women in the United States. Uterine transplantation (UTx) is an emerging treatment for UFI, particularly in…
2018 American Transplant Congress
Maternal and Fetal Outcomes in Living Kidney Donors in Korea
H. Lee,¹ K. Yoo,² M. Yu,¹ Y. Kim.¹
¹Seoul National University, Seoul, Korea; ²Dongguk University College of Medicine, Gyeongju, Korea.
Background. Mild elevation of blood pressure after unilateral nephrectomy may contribute to elevate gestational hypertension or preeclampsia in women donors. To date, impact of kidney…
2018 American Transplant Congress
Donor Specific Antibodies Increase the Risk of Preeclampsia in Pregnant Kidney Transplant Recipients
M. Lubetzky, T. Muthukumar, J. Lee, J. Lee, C. Hartono, L. Mahla, D. Serur, D. Dadhania.
Weill Cornell-New York Presbyterian, NY, NY.
Kidney transplant recipients are at an increased risk for pregnancy-associated complications including preeclampsia (PEC). Endothelial injury in the placenta is a hallmark of PEC. The…
2018 American Transplant Congress
Pregnancy Outcomes after Living Liver Donation
G. Lee, E. Sonnenberg, K. Olthoff, D. Goldberg, P. Abt.
Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA; Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA.
Introduction: Women who have previously donated a kidney are at increased risk of pre-eclampsia. Nearly half of living liver donors are women of child-bearing age.…
2018 American Transplant Congress
Outcomes of Pregnancies in Female Liver Transplant Recipients
L. Coscia,¹ D. Armenti,¹ P. Patel,² S. Constantinescu,^1,3 M. Moritz.^1,2,4
¹Transplant Pregnancy Registry International, Gift of Life Institute, Philadelphia, PA; ²Surgery, Lehigh Valley Health Network, Allentown, PA; ³Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA; ⁴Surgery, Morsani College of Medicine, Tampa, FL.
The purpose of this study is to describe 544 pregnancies in 278 liver transplant recipients reporting to the Transplant Pregnancy Registry International (TPR) from 1991…
2018 American Transplant Congress
Memory T Cell Dysfunction after Pregnancy Alloimmunization Prolongs Transplant Survival
P. Porrett,¹ J. Cohen,² R. Xu,¹ E. Lewis,³ M. Elovitz,³ E. Wherry,⁴ D. Sawinski.²
¹Surgery, University of Pennsylvania, Philadelphia, PA; ²Medicine, University of Pennsylvania, Philadelphia, PA; ³OBGyn, University of Pennsylvania, Philadelphia, PA; ⁴Microbiology, University of Pennsylvania, Philadelphia, PA.
Background Pregnancy alloimmunization can preclude donor compatibility and may diminish transplant lifespan. While these consequences may be attributed to immunologic memory responses that endanger an…
2018 American Transplant Congress
First Birth after Uterus Transplant in the US
L. Johannesson, R. Gunby, Jr., T. Anthony, G. McKenna, E. Koon, A. Warren, G. dePrisco, J. Mitchell, J. Putman, K. Wallis, G. Klintmalm, G. Testa.
Baylor University Medical Center, Dallas, TX.
Introduction - Uterus Transplantation (UTx) is the first available treatment for women with Absolute Uterine Infertility (AUI). It allows the affected female to carry her…
2018 American Transplant Congress
Acquired Resistance to Transplantation Tolerance as a Result of Prior Pregnancy Requires B Cells
A. Suah,¹ S. Khiew,¹ J. Young,¹ D. Yin,¹ Q. Wang,¹ M. Alegre,² A. Chong.¹
¹Surgery, Univeristy of Chicago Medicine, Chicago, IL; ²Medicine, University of Chicago, Chicago, IL.
Introduction: Clinical data suggest allogeneic pregnancy is a sensitizing event; yet, recent data from mouse models indicates it induces fetal-specific regulatory T cell (Treg) expansion…
2017 American Transplant Congress
Induction of Sensitization and Resistance to Transplant Tolerance by Allogeneic Pregnancy.
A. Suah,¹ J. Young,¹ S. Hsu-Wei Khiew,¹ Q. Wang,¹ D. Yin,¹ M.-L. Alegre,² A. Chong.¹
¹Department of Surgery, University of Chicago, Chicago, IL; ²Department of Medicine, University of Chicago, Chicago, IL
Background: Clinical data suggest allogeneic pregnancy is a sensitizing event; yet, recent data from mouse models suggest it induces fetal-specific regulatory T cell (Treg) expansion…