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Articles tagged "Prediction models"

  • 2021 American Transplant Congress

    Relationship of Functional Frailty and Radiographic Sarcopenia to Outcomes After Liver Transplant

    S. L. Olson, P. Polineni, W. Schwartz, O. Siddiqui, L. Zhao, D. Ganger, D. P. Ladner

    Comprehensive Transplant Center, Northwestern University, Chicago, IL

    *Purpose: Frailty and sarcopenia are associated with increased risk of hospitalization and mortality in end stage liver disease patients. Frailty can be measured clinically using…
  • 2021 American Transplant Congress

    Risk Classification Models for Kidney Graft Failure

    M. G. Naik1, K. Budde1, D. Telmo Neves2

    1Medical Department, Division of Nephrology and Internal Intensive Care Medicine, Charité, Berlin, Germany, 2Intelligent Analytics for Massive Data, German Research Center for Artificial Intelligence, Berlin, Germany

    *Purpose: Longterm graft survival after kidney transplantation is stagnant over the last decades. An individual risk assessment for graft failure is needed. In our project…
  • 2021 American Transplant Congress

    A Machine Learning-Based Predictive Model for Outcome of Covid-19 in Kidney Transplant Recipients

    I. Revuelta1, F. Santos-Arteaga2, D. Di Caprio3, E. Montagud-Marrahi1, F. Cofan1, J. Torregrosa1, M. Bodro4, A. Moreno4, P. Ventura-Aguiar1, D. Cucchiari1, N. Esforzado1, G. Piñeiro1, J. Ugalde-Altamirano1, J. Campistol1, A. Alcaraz5, B. Bayès1, E. Poch1, F. Oppenheimer1, F. Diekmann1

    1Department of Nephrology and Kidney Transplant, Hospital Clinic, Barcelona, Spain, 2Faculty of Economics and Management, Free University of Bolzano, Bolzano, Italy, 3Department of Economics and Management, University of Trento, Trento, Italy, 4Department of Infectious Diseases, Hospital Clinic, Barcelona, Spain, 5Department of Urology, Hospital Clinic, Barcelona, Spain

    *Purpose: Health systems need tools to deal with COVID-19, especially for high-risk population,such as transplant recipients. Predictive models are necessary to improve management of patients…
  • 2020 American Transplant Congress

    Using Artificial Intelligence Tools for Identification of High Risk Transplant Recipients for Focused Management

    M. A. Schnitzler1, C. Dagli2, C. Canfield2, N. Dzebisashvili3, C. Varma1, D. Axelrod4, K. Lentine1, R. Ouseph1, H. Randall1

    1Saint Louis University, St. Louis, MO, 2Missouri S&T, Rolla, MO, 3CareDx, Brisbane, CA, 4University of Iowa, Iowa City, IA

    *Purpose: Resources for post-transplant patient monitoring are limited. Statistical stratification can facilitate focused attention on highest risk patients. We developed a monitoring tool for graft…
  • 2020 American Transplant Congress

    The Use of dd-cfDNA as a Predictive Tool for Future Proteinuria

    S. Jordan1, P. Sood2, J. Bromberg3, D. Brennan4

    1Cedars-Sinai, Los Angeles, CA, 2University of Pittsburgh Medical Center, Pittsburgh, PA, 3University of Maryland, Baltimore, MD, 4The Johns Hopkins Hospital, Baltimore, MD

    *Purpose: Most allografts with proteinuria >1500 mg/dL have new glomerular pathology. In contrast, lower levels of proteinuria are generally associated with non-glomerular, nonspecific histologic changes.…
  • 2020 American Transplant Congress

    Anticipated Cost Savings of Using Lungs from Hepatitis C-Positive Lung Donors for Hepatitis C-Negative Recipients

    K. Ryland1, J. Mallea2, J. Moriarty3, L. White4, B. Borah5, J. Naessens3

    1Transplantation, Mayo Clinic, Jacksonville, FL, 2Medicine, Mayo Clinic, Jacksonville, FL, 3Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, 4Health Sciences Research, Mayo Clinic, Jacksonville, FL, 5Health Sciences Research, Mayo Clinic, Rochester, MN

    *Purpose: We assessed the cost savings generated by additional organ availability due to utilizing lungs from hepatitis-C infected donors for transplantation in comparison to existing…
  • 2020 American Transplant Congress

    The 1st Year Posttransplant Course Reliably Predicts Kidney Graft Survival up to 15 Years Using a Machine Learning-Based Modeling Approach

    W. Gwinner, M. Gietzelt, R. Hanna, A. A. Khalifa, M. Hallensleben, M. Marschollek, H. Haller, J. H. Braesen, I. Scheffner

    Hannover Medical School, Hannover, Germany

    *Purpose: Identification of patients at risk for graft failure can improve individual surveillance and early therapeutic interventions. We used a well-documented patient cohort to establish…
  • 2020 American Transplant Congress

    A Machine-Learning Approach for Estimating Likelihood of Transplant Benefit from Older-Donor Kidneys

    T. Pruett1, P. Martin2, D. Gupta3

    1University of Minnesota, Minneapolis, MN, 2University of Texas, Austin, TX, 3McCombs School of Business, University of Texas, Austin, TX

    *Purpose: There is a shortage of transplantable kidneys in the US. Yet, the discard rate among older donors (55+) is approx. 38% per year. The…
  • 2020 American Transplant Congress

    Tacrolimus Concentrations Are Associated with Measures of Body Composition in Adult Kidney Transplant Recipients

    K. S. Parker1, B. Derstine2, J. Sullivan2, S. Wang2, A. Mazurek1, D. Cron1, S. Waits1

    1Department of Surgery, University of Michigan, Ann Arbor, MI, 2Morphomic Analysis Group, University of Michigan, Ann Arbor, MI

    *Purpose: Tacrolimus (Tacro) is essential for kidney transplant immunosuppression but has a narrow therapeutic window. Tacro dosing preventing rejection must be balanced with potential delayed…
  • 2020 American Transplant Congress

    Predictive Validity of Functional Status on Mortality in Adult Kidney Transplant Recipients

    N. Chu, Z. Shi, D. Segev, M. McAdams Demarco

    Johns Hopkins, Baltimore, MD

    *Purpose: Frailty and disabilities, though not routinely measured, are highly prevalent in kidney transplant (KT) recipients and predict poor post-transplant outcomes. The Karnofsky Performance Scale…
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