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American Transplant Congress abstracts

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Articles tagged "Prediction models"

  • 2022 American Transplant Congress

    Processing Personal Activity Tracker (PAT) Through Artificial Intelligence (AI) is a Promising Method to Identify Patterns of Physical Activity in Liver Transplant (LT) Candidates

    A. Duarte-Rojo1, P. M. Bloomer1, J. M. Jakicic2, E. Sejdic3

    1University of Pittsburgh Medical Center, Pittsburgh, PA, 2Adventa Health, Orlando, FL, 3University of Pittsburgh, Pittsburgh, PA

    *Purpose: Prehabilitation is recommended for frail and pre-frail LT candidates. Although home-based programs are generalizable, their success depends on the adherence to an exercise prescription.…
  • 2022 American Transplant Congress

    A Novel Prospective Validation Trial Of Multiple Blood-based RNA Signature Assays Pre And Post Kidney Transplant To Predict Rejection

    L. Gallon1, P. O'Connell2, A. Chang3, M. Donovan4

    1Northwestern Univ, Chicago, IL, 2Westmead Inst, Sydney, Australia, 3Univ of Chicago, Chicago, IL, 4Verici Dx, Franklin, TN

    *Purpose: The accuracy and utility of clinically defined and analytically validated predictive biomarkers in kidney transplantation is limited. We leveraged prior feasibility blood-RNA studies to…
  • 2022 American Transplant Congress

    Proteomic Profiling of Bile from Human Livers Undergoing Viability Assessment via Normothermic Machine Perfusion Prior to Transplantation

    A. M. Thorne1, J. C. Wolters2, F. Kuipers1, R. J. Porte1, V. E. de Meijer1

    1University Medical Center Groningen, Groningen, Netherlands, 2University of Groningen, Groningen, Netherlands

    *Purpose: Normothermic machine perfusion (NMP) has gained increasing traction as a method to assess the viability of high-risk donor livers. To avoid post-transplant biliary complications,…
  • 2022 American Transplant Congress

    Cold Pulsatile Perfusion Resistance of Deceased Donor Kidneys Mainly Dependent on Renal Mass, Donor Age and Donor AKI, Other Donor Factors Have Minimal Impact

    D. Keith, E. Lessmann

    Kidney Transplant, Sacred Heart Hospital, Pensacola, FL

    *Purpose: To determine the factors influencing resistance to flow during cold pulsatile perfusion preservation (CPPP) of deceased donor kidneys.*Methods: All donor kidneys procured for possible…
  • 2022 American Transplant Congress

    Predicting Long Term Kidney-Allograft Failure: Machine Learning vs Traditional Statistical Models

    A. Truchot1, M. Raynaud1, c. lefaucheur2, O. Aubert1, A. Loupy1

    1Paris Transplant Group, Paris, France, 2Hôpital Saint-Louis, Paris, France

    *Purpose: Prognostic models have been developed in organ transplant over the past years using traditional statistical models. However, whether these are outperformed by machine learning…
  • 2022 American Transplant Congress

    Waitlist Meldna Variation One-year Prior To Liver Transplant Predicts Length Of Stay At The Time Of Transplant

    L. Pruinelli1, S. Olson1, J. Zhou1, M. Nguyen1, J. Schold2, T. Pruett1, S. Ma1, G. Simon1

    1University of Minnesota, Minneapolis, MN, 2Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: MELDNa is used to estimate 90-day mortality in the waitlist. MELDNa variation between cross-sections has shown a better predictivity than when analyzed as a…
  • 2022 American Transplant Congress

    Predicting Urinary Tract Infections Requiring Hospitalization in Living Donor Kidney Transplant Recipients

    A. Dinh, T. Copeland, D. Adey, E. Ku

    UCSF, San Francisco, CA

    *Purpose: Urinary tract infections (UTI) requiring hospitalization are common after kidney transplantation and are associated with increased risk of graft failure. Identifying patients at high…
  • 2022 American Transplant Congress

    Six-Month Outcomes Among Lung Transplant Patients with COVID-19

    L. D. Mahan, J. Rose, M. Mohanka, A. Banga

    UT Southwestern Medical Center, Dallas, TX

    *Purpose: There is limited data on the outcomes beyond the acute illness among lung transplant (LT) patients with Coronavirus disease 2019 (COVID-19). The current study…
  • 2022 American Transplant Congress

    Tracking of Donor Reactive T Cell Clones Can Be Used to Diagnose or Even Predict Kidney Transplant Rejection

    J. M. Mathew1, Y. Sambandam1, M. Kandpal1, J. He1, G. Perottino1, B. Banbury2, P. Fields2, L. Gallon1, J. R. Leventhal1

    1Northwestern University, Chicago, IL, 2Adaptive Biotechnologies, Seattle, WA

    *Purpose: Transplant (Tx) rejection currently requires an invasive biopsy for diagnosis. We have tested if serial quantitation of donor reactive T cell clones (DRTC) can…
  • 2022 American Transplant Congress

    Mortality in Solid Organ Transplant Recipients with a Pretransplant Cancer Diagnosis

    A. Hart1, R. Pfeiffer2, B. Morawski3, C. Lynch4, Y. Zeng5, K. Pawlish6, K. Yu7, D. Hurley8, E. Engels7

    1Hennepin Healthcare, University of Minnesota, Minneapolis, MN, 2Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 3Cancer Registry of Idaho, Boise, ID, 4Epidemiology, University of Iowa, Iowa City, IA, 5North Dakota Statewide Cancer Registry, Grand Forks, ND, 6New Jersey State Cancer Registry, Trenton, NJ, 7Infections and Immunoepidemiology Branch, National Cancer Institute, Bethesda, MD, 8University of South Carolina, Columbia, SC

    *Purpose: Transplant-associated immunosuppression may cause cancer recurrence in patients with a pretransplant cancer, but little is known about outcomes among these recipients.*Methods: We used data…
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