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Articles tagged "Post-transplant malignancy"

  • 2018 American Transplant Congress

    Prostate Cancer Characteristics in Men on Immunosuppressive Medications

    M. Eltemamy, A. Elshafei, A. Salah, Y. Nyame, H. Arora, A. Wee, V. Krishnamurthi, S. Jones.

    Cleveland Clinic, Cleveland.

    INTRODUCTION: To assess the prevalence of prostate cancer (PCa) in men receiving immunosuppressive medications undergoing transrectal ultrasound guided (TRUS) prostate biopsy.METHODS: A total of 468…
  • 2018 American Transplant Congress

    Donor Derived Renal Cell Carcinoma (RCC) Transmission Events 2008-2016: A Report of the OPTN Disease Transmission Advisory Committee (DTAC)

    M. Pavlakis, M. Michaels, S. Tlusty, N. Turgeon, G. Vece, C. Wolfe, R. Wood, M. Nalesnik.

    OPTN/UNOS, RCC Work Group.

    Background: RCC is the most common renal tumor reported to the OPTN and reviewed by DTAC for assessment of potential donor transmission. Organs with concern…
  • 2018 American Transplant Congress

    Induction Agents and Post-Transplant Malignancies in Kidney Transplants: An Examination of Outcomes at a Large Volume Center over 20 Years

    D. Livingston-Rosanoff, X. Wang, G. Leverson, D. Kaufman, D. Foley.

    Division of Transplant Surgery, University of Wisconsin, Madison, WI.

    Introduction: Induction agents have a profound effect on the immune milieu at the time of kidney transplantation. However, evaluation of their long-term effects on graft…
  • 2018 American Transplant Congress

    The Influence of a Conversion to Sirolimus-Based Immunosuppression on Non-Melanomatous Skin Cancer Incidence in Kidney Transplant Recipients over Long Term Follow Up

    F. Daly,1 P. O'Kelly,1 F. Moloney,2 D. Sexton,1 P. Conlon.1

    1Department of Nephrology and Transplantation, Beaumont Hospital, Dublin, Ireland; 2Department of Dermatology, Mater Misericordiae University Hospital, Dublin, Ireland.

    Background: The CONVERT trial found a reduced incidence of malignancy amongst renal transplant recipients over 2 years of follow up with a conversion from calcineurin…
  • 2018 American Transplant Congress

    Outcomes of Organ Transplantation from Donors with Cancer History

    Z. Guo,1 X. He,1 S. Huang.1

    1Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; 2Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology, Sun Yat-sen University, Guangzhou, China; 3Guangdong Provincial International Cooperation Base of Science and Technology, Sun Yat-sen University, Guangzhou, China.

    Purpose: The inherent challenges of selecting an acceptable donor for each of the increasing numbers and acuity of recipients has led programs to take increased…
  • 2018 American Transplant Congress

    Organ Transplantation Associated with High Incidence of Anal Cancer and Pre-Cancer Lesions among HIV-Infected Women and Men

    P. Chin-Hong,1 B. Barin,2 M. Berry,1 M. DaCosta,1 T. Darragh,1 L. Rosenthal,3 S. Bartlett,4 D. Dieterich,5 F. Poordad,6 N. Nissen,6 M. Wong,7 P. Stock,1 J. Palefsky.1

    1University of California, San Francisco, San Francisco; 2EMMES, Rockville; 3Columbia University, New York; 4University of Maryland, Baltimore; 5Icahn School of Medicine at Mount Sinai, New York; 6Cedars-Sinai Medical Center, Los Angeles; 7Beth Israel Deaconess Medical Center, Boston.

    Objective: HIV-infected women and men and transplant recipients are two populations at increased risk of HPV-associated anal cancer but there is little published data. We…
  • 2018 American Transplant Congress

    Different Expression Patterns of Exosomal miRNAs under Cyclosporin A and Rapamycin Treatment in Distinct Aggressiveness Colorectal Carcinomas

    V. Tubita,1 M. Ramírez-Bajo,1 J. Lozano,2 D. Moya-Rull,1 J. Rovira,3 J. Campistol,4,5,6 F. Diekmann,1,4,5,6 I. Revuelta.1,4,5,6

    1Experimental Laboratory of Nefrology and Kidney Transplant (LENIT). Biomedical Research Clinic Foundation (FCRB), Barcelona, Spain; 2Bioinformatics Platform, CIBEREHD, Barcelona, Spain; 3Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; 4Renal Transplant Unit. Department of Nephrology and Kidney Transplant. Hospital Clinic, Barcelona, Spain; 5REDinREN, Madrid, Spain; 6Barcelona University, Barcelona, Spain.

    The aggressiveness of colorectal cancer (CRC) in kidney transplantation is much more significant than the increase in its incidence compared with the general population. The…
  • 2018 American Transplant Congress

    Do We Need to Worry about EBV DNAemia in the Late Post-Transplant Period?

    M. Morton,1 K. Daga,2 P. Klapper,2 M. Picton,1 P. Vallely.2

    1Department of Renal Medicine, Manchester Royal Infirmary, Manchester, United Kingdom; 2University of Manchester, Manchester, United Kingdom.

    Background: Despite detectable Epstein-Barr virus (EBV) in blood, kidney transplant patients (KTR) may have no apparent clinical consequence. This study aims to explore the clinical…
  • 2018 American Transplant Congress

    Racial Differences in Rates of Malignant and Infectious Cutaneous Genital Disease after Solid Organ Transplantation

    M. Larijani,1 K. Nadhan,1 J. Abbott,1 A. Doyle,2 C. Chung.1

    1Department of Dermatology, Drexel University, Philadelphia, PA; 2Department of Internal Medicine, University of Virginia, Charlottesville, VA.

    Purpose: To describe the prevalence and types of genital lesions observed in OTRsMethods: This retrospective review included 496 OTRs who underwent full skin examination at…
  • 2017 American Transplant Congress

    BK Virus Infection and Risk of Urinary Tract Cancers Among Kidney Transplant Patients in the Transplant Cancer Match Study.

    G. Gupta,1 S. Kuppachi,2 R. Kalil,2 C. Buck,3 C. Lynch,2 E. Engels.3

    1Virginia Commonwealth University, Richmond; 2University of Iowa, Iowa City; 3National Cancer Institute, Bethesda

    Background: Recent case series describe expression of BK virus (BKV) in tumor tissue obtained from renourinary cancers in kidney transplant recipients (KTRs). Thus, BKV may…
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