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Articles tagged "Post-transplant malignancy"

  • 2018 American Transplant Congress

    Outcomes of Organ Transplantation from Donors with Cancer History

    Z. Guo,1 X. He,1 S. Huang.1

    1Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; 2Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology, Sun Yat-sen University, Guangzhou, China; 3Guangdong Provincial International Cooperation Base of Science and Technology, Sun Yat-sen University, Guangzhou, China.

    Purpose: The inherent challenges of selecting an acceptable donor for each of the increasing numbers and acuity of recipients has led programs to take increased…
  • 2018 American Transplant Congress

    Organ Transplantation Associated with High Incidence of Anal Cancer and Pre-Cancer Lesions among HIV-Infected Women and Men

    P. Chin-Hong,1 B. Barin,2 M. Berry,1 M. DaCosta,1 T. Darragh,1 L. Rosenthal,3 S. Bartlett,4 D. Dieterich,5 F. Poordad,6 N. Nissen,6 M. Wong,7 P. Stock,1 J. Palefsky.1

    1University of California, San Francisco, San Francisco; 2EMMES, Rockville; 3Columbia University, New York; 4University of Maryland, Baltimore; 5Icahn School of Medicine at Mount Sinai, New York; 6Cedars-Sinai Medical Center, Los Angeles; 7Beth Israel Deaconess Medical Center, Boston.

    Objective: HIV-infected women and men and transplant recipients are two populations at increased risk of HPV-associated anal cancer but there is little published data. We…
  • 2018 American Transplant Congress

    Different Expression Patterns of Exosomal miRNAs under Cyclosporin A and Rapamycin Treatment in Distinct Aggressiveness Colorectal Carcinomas

    V. Tubita,1 M. Ramírez-Bajo,1 J. Lozano,2 D. Moya-Rull,1 J. Rovira,3 J. Campistol,4,5,6 F. Diekmann,1,4,5,6 I. Revuelta.1,4,5,6

    1Experimental Laboratory of Nefrology and Kidney Transplant (LENIT). Biomedical Research Clinic Foundation (FCRB), Barcelona, Spain; 2Bioinformatics Platform, CIBEREHD, Barcelona, Spain; 3Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; 4Renal Transplant Unit. Department of Nephrology and Kidney Transplant. Hospital Clinic, Barcelona, Spain; 5REDinREN, Madrid, Spain; 6Barcelona University, Barcelona, Spain.

    The aggressiveness of colorectal cancer (CRC) in kidney transplantation is much more significant than the increase in its incidence compared with the general population. The…
  • 2018 American Transplant Congress

    Do We Need to Worry about EBV DNAemia in the Late Post-Transplant Period?

    M. Morton,1 K. Daga,2 P. Klapper,2 M. Picton,1 P. Vallely.2

    1Department of Renal Medicine, Manchester Royal Infirmary, Manchester, United Kingdom; 2University of Manchester, Manchester, United Kingdom.

    Background: Despite detectable Epstein-Barr virus (EBV) in blood, kidney transplant patients (KTR) may have no apparent clinical consequence. This study aims to explore the clinical…
  • 2018 American Transplant Congress

    Racial Differences in Rates of Malignant and Infectious Cutaneous Genital Disease after Solid Organ Transplantation

    M. Larijani,1 K. Nadhan,1 J. Abbott,1 A. Doyle,2 C. Chung.1

    1Department of Dermatology, Drexel University, Philadelphia, PA; 2Department of Internal Medicine, University of Virginia, Charlottesville, VA.

    Purpose: To describe the prevalence and types of genital lesions observed in OTRsMethods: This retrospective review included 496 OTRs who underwent full skin examination at…
  • 2018 American Transplant Congress

    Decreased Post Heart Transplant Survival with Epstein-Barr Virus Mismatch in the Current Era

    M. Kittleson, J. Patel, E. Kransdorf, S. Dimbil, R. Levine, S. Mersola, D. Geft, D. Chang, L. Czer, J. Kobashigawa.

    Cedars Sinai Medical Center, Los Angeles.

    Purpose: Epstein-Barr virus (EBV) has been implicated in a multitude of cancers, including B-cell lymphoma, Burkitt's lymphoma, CNS lymphoma, gastric cancer and nasopharyngeal carcinoma. Previous…
  • 2018 American Transplant Congress

    Development of an Expert Consensus Guideline for Skin Cancer Screening in Solid Organ Transplant Recipients

    L. Crow,1 S. Arron,1 C. Chung,2 A. Jambusaria-Pahlajani,3 S. Lowenstein,1 On behalf of the Transplant Skin Cancer Network.

    1Dermatology, University of California San Francisco, San Francisco, CA; 2Dermatology, Drexel Medicine, Philadelphia, PA; 3Dermatology, Baylor, Scott & White Health, Round Rock, TX.

    Importance Skin cancer is the most common malignancy affecting solid organ transplant recipients (SOTR). Transplant recipients have a significantly increased risk for developing both melanoma…
  • 2018 American Transplant Congress

    Decreased Expression of Pro-Carcinogenic Genes Following Tacrolimus to Sirolimus Conversion in Liver Transplant Recipients

    M. Bhat,1 E. Pasini,1 C. Baciu,1 S. Kurian,2 J. Levitsky.3

    1Multi Organ Transplant Program, University Health Network, Toronto, Canada; 2Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA; 3Division of Gastroenterology & Hepatology, Department of Medicine, Northwestern University, Chicago.

    Long-term survival post-transplant is significantly impacted by malignancy. mTOR-inhibitors (mTORis) have anti-neoplastic properties and are associated with a decreased incidence of certain malignancies compared to…
  • 2018 American Transplant Congress

    Immunosuppression Does Not Affect Adverse Pathological Outcomes in Men Who Underwent Radical Prostatectomy

    M. Eltemamy, A. Elshafei, Y. Nyame, A. Crane, A. Wee, V. Krishnamurthi, E. Klein, S. Jones.

    Cleveland Clinic, Cleveland.

    Introduction: The impact of imuunosuppression (IS) on biological aggressiveness of cancer prostate (PCa) is unclear. We aim to assess the adverse pathological (AP) outcomes in…
  • 2017 American Transplant Congress

    Donor Derived and BK Virus Positive Urologic Cancers After Renal Transplantation.

    V. Hellström,1 G. Tufveson,1 A. Wallgren,2 A. Loskog,2 E. Larsson,2 T. Töttermann,2 M. Bengtsson,2 A. Laurell,2 C. Lundberg,1 B. Holmström,1 G. Enblad,2 T. Lorant.1

    1Department of Surgical Sciences, Uppsala University, Uppsala, Sweden; 2Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden

    Background. Donor-derived tumours in organ recipients develop from donor tissue with no known pre-existing malignancy in the donor. In addition, polyoma BK virus (BKV) might…
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