Articles tagged "Post-transplant malignancy"

2019 American Transplant Congress
Impact of Everolimus on Secondary Nonmelanoma Skin Cancer Prevention in Solid Organ Transplant Recipients
B. Clark¹, D. D. Ramirez¹, A. Carlson¹, B. Sirandas¹, C. Truax¹, L. Smith¹, I. Hall²
¹Solid Organ Transplant, University of Utah Health, Salt Lake City, UT, ²Nephrology and Hypertension, University of Utah Health, Salt Lake City, UT
*Purpose: Over half of solid organ transplant recipients (SOTR) develop nonmelanoma skin cancers (NMSC) and up to 80% experience recurrence. Many immunosuppressive drugs are known…
2019 American Transplant Congress
Post-Transplant Lymphoproliferative Disorders after Living-Donor Liver Transplantation: A Retrospective Cohort Study in 1,900 Cases of Single Center Experience
T. Tajima¹, K. Hata¹, H. Haga², M. Nishikori³, J. Kusakabe¹, I. Tamaki¹, T. Ito¹, T. Kaido¹, A. Takaori-Kondo³, S. Uemoto¹
¹Div. of HBP Surgery and Transplantation, Dept. of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan, ²Dept. of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan, ³Dept. of Hematology and Oncology, Kyoto University Graduate School of Medicine, Kyoto, Japan
*Purpose: Post-transplant lymphoproliferative disorders (PTLD) is relatively rare but the most common, life-threatening neoplasms after organ transplantation. Because of their heterogeneity from benign to malignant…
2019 American Transplant Congress
Incidence and Mortality of Renal Cell Carcinoma after Kidney Transplantation: A Meta-Analysis
A. Chewcharat¹, C. Thongprayoon², B. Boonpheng³, A. Torres-Ortiz⁴, M. A Mao², N. J Khoury⁵, W. Cheungpasitporn⁴
¹Harvard T.H. Chan, Boston, MA, ²Mayo Clinic, Rochester, MN, ³East Tennessee State University, Johnson City, TN, ⁴University of Mississippi Medical Center, Jackson, MS, ⁵Henry Ford Hospital, Detroit, MI
*Purpose: The incidence and mortality of renal cell carcinoma (RCC) after kidney transplantation (KTx) remain unclear. This study's aims were 1) to investigate the pooled…
2019 American Transplant Congress
Lower Incidence of Posttransplant Malignancies under Vitamin D (Calcidiol) Treatment in Kidney Transplantation
I. Revuelta¹, V. Tubita², J. Ugalde¹, D. Cucchiari¹, F. Oppenheimer¹, F. Diekmann¹, J. Campistol¹, J. Torregrosa¹
¹Department of Nephrology and Kidney Transplant, Hospital Clinic, Barcelona, Spain, ²Experimental Laboratory of Nephrology and Kidney Transplant, IDIBAPS, Barcelona, Spain
*Purpose: An increasing body of evidence has emerged on the role of 1α,25-dihydroxyvitamin D3[1,25(OH) 2 D] in cell differentiation, which seems to have regulation properties…
2019 American Transplant Congress
Characterization Of Microscopic Hematuria Following Renal Transplant
M. L. McDonald¹, T. N. Duong², N. Datta², H. A. Gritsch¹, S. Bunnapradist²
¹Department of Urology, Kidney and Pancreas Transplant Programs, UCLA, Los Angeles, CA, ²Division of Nephrology, Kidney and Pancreas Programs, UCLA, Los Angeles, CA
*Purpose: The American Urological Association (AUA) recommends a CT Urography and cystoscopy for the evaluation of a single episode of microscopic hematuria (MH) in the…
2018 American Transplant Congress
Donor Derived Renal Cell Carcinoma (RCC) Transmission Events 2008-2016: A Report of the OPTN Disease Transmission Advisory Committee (DTAC)
M. Pavlakis, M. Michaels, S. Tlusty, N. Turgeon, G. Vece, C. Wolfe, R. Wood, M. Nalesnik.
OPTN/UNOS, RCC Work Group.
Background: RCC is the most common renal tumor reported to the OPTN and reviewed by DTAC for assessment of potential donor transmission. Organs with concern…
2018 American Transplant Congress
Induction Agents and Post-Transplant Malignancies in Kidney Transplants: An Examination of Outcomes at a Large Volume Center over 20 Years
D. Livingston-Rosanoff, X. Wang, G. Leverson, D. Kaufman, D. Foley.
Division of Transplant Surgery, University of Wisconsin, Madison, WI.
Introduction: Induction agents have a profound effect on the immune milieu at the time of kidney transplantation. However, evaluation of their long-term effects on graft…
2018 American Transplant Congress
The Influence of a Conversion to Sirolimus-Based Immunosuppression on Non-Melanomatous Skin Cancer Incidence in Kidney Transplant Recipients over Long Term Follow Up
F. Daly,¹ P. O'Kelly,¹ F. Moloney,² D. Sexton,¹ P. Conlon.¹
¹Department of Nephrology and Transplantation, Beaumont Hospital, Dublin, Ireland; ²Department of Dermatology, Mater Misericordiae University Hospital, Dublin, Ireland.
Background: The CONVERT trial found a reduced incidence of malignancy amongst renal transplant recipients over 2 years of follow up with a conversion from calcineurin…
2018 American Transplant Congress
Outcomes of Organ Transplantation from Donors with Cancer History
Z. Guo,¹ X. He,¹ S. Huang.¹
¹Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; ²Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology, Sun Yat-sen University, Guangzhou, China; ³Guangdong Provincial International Cooperation Base of Science and Technology, Sun Yat-sen University, Guangzhou, China.
Purpose: The inherent challenges of selecting an acceptable donor for each of the increasing numbers and acuity of recipients has led programs to take increased…
2018 American Transplant Congress
Organ Transplantation Associated with High Incidence of Anal Cancer and Pre-Cancer Lesions among HIV-Infected Women and Men
P. Chin-Hong,¹ B. Barin,² M. Berry,¹ M. DaCosta,¹ T. Darragh,¹ L. Rosenthal,³ S. Bartlett,⁴ D. Dieterich,⁵ F. Poordad,⁶ N. Nissen,⁶ M. Wong,⁷ P. Stock,¹ J. Palefsky.¹
¹University of California, San Francisco, San Francisco; ²EMMES, Rockville; ³Columbia University, New York; ⁴University of Maryland, Baltimore; ⁵Icahn School of Medicine at Mount Sinai, New York; ⁶Cedars-Sinai Medical Center, Los Angeles; ⁷Beth Israel Deaconess Medical Center, Boston.
Objective: HIV-infected women and men and transplant recipients are two populations at increased risk of HPV-associated anal cancer but there is little published data. We…