Articles tagged "Plasmapheresis"

2016 American Transplant Congress
Utilization of Plasmapheresis and High Dose of Immunoglobulins in the Treatment of the High Level of De Novo Donor Specific Antibodies for the Successful Islet Allotransplantation.
J. Solomina,¹ Z. Tekin,¹ S. Matosz,¹ K. Golab,¹ C. Thomas,² J. Golebiewska,³ S. Ramachandran,¹ L. Schenck,¹ W. Chon,¹ M. Tibudan,¹ N. Marek-Trzonkowska,⁴ J. Millis,¹ P. Witkowski.¹
¹Surgery, University of Chicago, Chicago, IL; ²Medicine, University of Chicago, Chicago, IL; ³Internal Medicine, Medical University of Gdansk, Gdansk, Poland; ⁴Family Medicine, Medical University of Gdansk, Gdansk, Poland.
Background.Development of donor specific antibodies (DSA) after islet transplantation has been a poor prognostic factor for graft survival, while no intervention is implemented. Here, we…
2016 American Transplant Congress
A2 Kidneys into B Recipients: Is Postoperative Anti-A1 Titer Monitoring Useful?
A. DeMers, R. Forbes, D. Moore, K. Smith, D. Shaffer.
Kidney and Pancreas Transplantation, Vanderbilt University Medical Center, Nashville, TN.
Background: Since the introduction of the new Kidney Allocation System in December 2014, our center implemented a protocol for transplanting A2 kidneys into B recipients…
2015 American Transplant Congress
Is Pretransplant Anti-A/B Antibody Removal Prerequisite for Successful ABO Incompatible Kidney Transplantation in Children?
S. Shishido,¹ T. Kawamura,¹ Y. Hamasaki,² Y. Takahashi,¹ Y. Hyodo,¹ Y. Itabashi,¹ H. Nihei,¹ T. Yonekura,¹ Y. Inaba,² Y. Yoshida,² K. Sakai,¹ A. Aikawa.¹
¹Nephrology, Toho University, School of Medicine, Tokyo, Japan; ²Pediatric Nephrology, Too University, School of Medicine, Tokyo, Japan.
Purpose: We have recently demonstrated that the long-term outcome of ABO incompatible living donor kidney transplantation (ABOiKT) in children was comparable to those of ABO…
2015 American Transplant Congress
Long-Term Excellent Results of ABO-Incompatible Kidney Transplantations at Multicenter Japanese Case Series
K. Tanabe,^１ H. Ishida,^１ K. Masutani,² Y. Okabe,³ M. Okumi,¹ H. Kitada,² T. Shimizu,⁴ H. Shirakawa.⁵
¹Urology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan; ²Kyushu University, Fukuoka, Japan; ³Surgery, Harasanshin Hospital, Fukuoka, Japan; ⁴Urology, Todachuo General Hospital, Toda, Saitama, Japan; ⁵Urology, Ohkubo Hospital, Shinjuku, Tokyo, Japan.
[Background]Although kidney transplantation (KT) is the most reassuring treatment for patients with ESRD, shortage of organ donation in Japan is crucial. This issue has forced…
2015 American Transplant Congress
Plasmapheresis – A Previously Unrecognised Risk Factor for BK Viraemia
E. Olayos,¹ K. Barraclough,² R. Walker,³ R. Masterson,² H. Peter,² C. Solomon.⁴
¹St Vincents Hospital, Fitroy, Victoria, Australia; ²Nephrology, Royal Melbourne Hospital, Parkville, Victoria, Australia; ³Nephrology, The Alfred Hospital, Prahran, Victoria, Australia; ⁴Nephrology, Western Hospital, Footscray, Victoria, Australia.
BK nephropathy is an important preventable cause of graft loss, with the only universally accepted risk factor being overall burden of immunosuppression. In the absence…
2015 American Transplant Congress
Excellent Outcomes of Prophylactic Rituximab Administration With Plasmapheresis in Kidney Transplant Recipients With Focal Segmental Glomerulosclerosis
M. Okumi,¹ Y. Miyauchi,² T. Yagisawa,¹ K. Unagami,¹ D. Toki,¹ K. Omoto,¹ H. Ishida,¹ K. Tanabe.¹
¹Urology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan; ²Urology, Ehime University, Matsuyama, Ehime, Japan.
[Background]The estimated recurrence rate of focal segmental glomerulosclerosis (FSGS) after kidney transplantation is approximately 30%. Relapse occurring immediately after transplantation is refractory to treatment and…
2015 American Transplant Congress
DSA Detected by ELISA-PRA Is Associated With High Risk for Development of AMR in Stable Kidney Transplant Recipients
D. Lee,¹ J. Kim,² B. Kim,³ M. Chun,⁴ I. Kim.⁵
¹Medicine, Division of Nephrology, Maryknoll General Hospital, Busan, Republic of Korea; ²Surgery, Maryknoll General Hospital, Busan, Republic of Korea; ³Laboratory Medicine, Maryknoll General Hospital, Busan, Republic of Korea; ⁴Pathology, Maryknoll General Hospital, Busan, Republic of Korea; ⁵Urology, Maryknoll General Hospital, Busan, Republic of Korea.
Background: Donor specific anti-HLA antibodies (DSA) are a major cause of antibody mediated rejection (AMR) and allograft loss, determining how to monitor patients for DSA…
2015 American Transplant Congress
Severe Refractory Skin Eruption Treated With Plasmapheresis in a Multivisceral Transplant Patient
J. Garcia,¹ T. Beduschi,¹ A. Tekin,¹ J. Fan,¹ S. Nishida,¹ G. Selvaggi,¹ G. Ciancio,¹ G. Burke,¹ C. Katsoufis,² L. Pizano,³ R. Vianna.¹
¹Miam Transplant Institute, University of Miami Miller School of Medicine, Miami, FL; ²Pediatrics, University of Miami Miller School of Medicine, Miami, FL; ³Surgery Critical Care, University of Miami Miller School of Medicine, Miami, FL.
3 year old African American male who underwent a multivisceral transplant due to gastroschisis. Crossmatch for T and B cells, PRA, DSA were negative. Induction…
2015 American Transplant Congress
Efficacy of Rituximab Sparing Protocol for ABO Incompatible Renal Transplant in Patients With Low Titers
S. Narumi,¹ Y. Watarai,¹ N. Goto,¹ T. Hiramitsu,¹ T. Yamamoto,¹ M. Tsujita,¹ M. Okada,¹ K. Futamura,¹ A. Takeda,² T. Kobayashi.³
¹Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan; ²Nephrology, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan; ³Applied Immunology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
[Introduction]Acute antibody mediated rejection (AMR) has been a major problem in ABO-incompatible kidney transplantation (ABOi-KTx), and currently mycophenolate mofetil and rituximab have been used to…
2015 American Transplant Congress
Expanding the Living Donor Pool: Results of ABO Incompatible Living Related Kidney Transplantation
T. Vowinkel,¹ S. Reuter,² C. Anthoni,¹ N. Senninger,¹ B. Suwelack,² H. Wolters.¹
¹Department of General and Visceral Surgery, University Hospital Muenster, Muenster, Germany; ²Department of Medicine D, University Hospital Muenster, Muenster, Germany.
Background: Organ shortage has led to an increase in living related kidney transplantation. Here we report on our program of expanding the living donor pool…