2022 American Transplant Congress
Early Experience Of 48-hour Normothermic Machine Perfusion In Human Kidneys Applying Urine Recirculation
*Purpose: Normothermic machine perfusion (NMP) of the kidney has been studied extensively during the past decade. Short-term kidney NMP has demonstrated promising results, however currently…2022 American Transplant Congress
Local Mesenchymal Stem Cell Therapy for the Ex Vivo Preservation of a Porcine Vascularized Composite Allograft with 24-hour Normothermic Machine Perfusion
*Purpose: Given therapeutic limitations in limb salvage, we sought to demonstrate the efficacy of combining local mesenchymal stem cells (MSCs) infusion with fresh whole blood…2022 American Transplant Congress
Perfusate Metabolites and Association with Pump Perfusion and Allograft Failure
*Purpose: While hypothermic machine perfusion (HMP) is associated with improved kidney graft viability, the exact biological mechanisms underlying this association are unknown. The goal of…2022 American Transplant Congress
Characterisation of Kidney-Specific Extracellular Vesicles During Isolated Organ Normothermic Machine Perfusion
*Purpose: Introduction: Normothermic machine perfusion (NMP) can evaluate and recondition deceased-donor kidneys but accurate biomarkers are needed to assess organ quality and to predict post-transplant…2022 American Transplant Congress
CD31+ Extracellular Vesicles in Ex Vivo Lung Perfusion Are Associated with Unsuitability for Transplant
*Purpose: Primary graft dysfunction (PGD) is an important cause of morbidity and mortality following lung transplantation and results in part from injuries sustained in the…2022 American Transplant Congress
Organ Care System Use in Liver Transplantation Shifts Preservation-Reperfusion Injury in Time and Space
Department of Transplant Pathology, University of Pittsburgh, Pittsburgh, PA
*Purpose: Liver allograft ischemia-reperfusion injury (IRI) causes early allograft dysfunction (EAD). The TransMedics Organ Care System (OCS) PROTECT trial for liver transplantation (NCT02522871) revealed that…2022 American Transplant Congress
Proteomic Profiling of Bile from Human Livers Undergoing Viability Assessment via Normothermic Machine Perfusion Prior to Transplantation
*Purpose: Normothermic machine perfusion (NMP) has gained increasing traction as a method to assess the viability of high-risk donor livers. To avoid post-transplant biliary complications,…2022 American Transplant Congress
The Association Between Renal Anatomy Data and Kidney Utilization
United Network for Organ Sharing, Richmond, VA
*Purpose: Renal anatomy data, such as hard arterial plaque or discoloration, can be available as PDF attachments uploaded to DonorNet during the organ evaluation process.…
American Transplant Congress abstracts