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American Transplant Congress abstracts

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Articles tagged "Perfusion"

  • 2022 American Transplant Congress

    Normothermic Organ Preservation: The New Standard?

    K. Mistry

    Sanford Health, Fargo, ND

    *Purpose: Normothermic perfusion (NMP) is a new technique that has been introduced into transplantation expanding capacity for organ utilization. NMP has been shown to be…
  • 2022 American Transplant Congress

    Significant Reduction of Troponin I Elaboration After Ischemia Minimization in the First Hour of Ex Vivo Xeno Heart Perfusion

    F. Pollok1, M. R. Connolly1, A. Calhoun1, Z. Habibabady1, S. Miura1, M. Ma1, S. Pratts1, L. Burdorf1, Y. Kan2, J. V. Layer2, J. V. Layer2, E. Tan2, R. Anand2, M. Li2, K. C. Hall2, M. E. Youd2, K. Stiede2, W. Qin2, M. Curtis2, A. Azimzadeh1, R. N. Pierson1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Cambridge, MA, 2eGenesis Inc., Cambridge, MA

    *Purpose: Previous studies showed that ischemia minimization (IM), accomplished by perfusing the heart xenograft during storage, prevents ‘initial cardiac xenograft dysfunction’ (ICXD) and enables prolonged…
  • 2022 American Transplant Congress

    Normal Saline vs Electrolyte-a Use Peri- and Post-Operatively in Adult Kidney Transplant Recipients

    K. R. Szempruch, A. D. Martschenko, H. Arora, R. Isaak, R. Prasad, P. Serrano

    UNC Medical Center, Chapel Hill, NC

    *Purpose: 0.9% normal saline (NS) has been used as the standard fluid replacement in kidney transplant recipients (KTRs) to prevent dehydration and to improve renal…
  • 2022 American Transplant Congress

    Liver and Kidney Transplantation from Donation After Circulatory Death Heart Donors in the US: Better Early Outcomes with Normothermic Regional Perfusion versus Cold Flush

    M. Rosenzweig1, R. Ruiz2, E. Martinez1, A. Gupta1, H. Fernandez1, S. Lee1, N. Onaca1, J. Bayer1, G. J. McKenna1, T. Ma1, G. Testa3, A. Wall1

    1Baylor University Medical Center, Dallas, TX, 2Baylor University Medical Center, Fort Worth, TX, 3Baylor Dallas, Dallas, TX

    *Purpose: Donation after circulatory death (DCD) heart donation is increasingly common in the US. The two methods for DCD heart donation are normothermic regional perfusion…
  • 2022 American Transplant Congress

    Efficacy and Safety of Angiotensin II Compared to Catecholamine Vasopressors as a First-Line Vasopressor for Perioperative Hypotension in Kidney Transplant Recipients

    G. Urias1, J. Benken1, A. Lichvar2, D. Pierce1, L. Andrews1, K. Dalton3, A. Datta1, H. Nishioka1, E. Benedetti1, S. Benken1

    1University of Illinois at Chicago, Chicago, IL, 2University of California San Diego Health, San Diego, CA, 3St. David's Healthcare, Austin, TX

    *Purpose: Perioperative use of catecholamine vasopressors (CV) in kidney transplantation (KT) have been associated with negative renal outcomes and the development of arrhythmias. A more…
  • 2022 American Transplant Congress

    Dynamic Changes and Roles of Specialized Pro-resolving Lipid Meditators in the Initiation and Resolution Process of Lung Ischemia-Reperfusion Injury in Rats

    H. Oda1, S. Tanaka1, M. Shinohara2, Y. Morimura1, Y. Yokoyama1, H. Kayawake1, Y. Yamada1, A. Ohsumi1, D. Nakajima1, H. Date1

    1Department of Thoracic Surgery, Kyoto University Graduate School of Medicine, Kyoto City, Japan, 2The Integrated Center for Mass Spectrometry, Kobe University Graduate School of Medicine, Kobe City, Japan

    *Purpose: Lung ischemia-reperfusion injury (IRI) is one of the significant complications after lung transplantation, which is a form of acute lung injury by robust inflammation.…
  • 2022 American Transplant Congress

    Normothermic Machine Perfusion in Liver Transplantation – Seven Year Experience at a Single North American Centre

    J. Hefler1, D. L. Izuierdo1, G. Meeberg2, M. Bral1, B. Anderson1, K. Dajani1, N. Kneteman1, D. L. Bigam1, A. Shapiro1

    1Department of Surgery, University of Alberta, Edmonton, AB, Canada, 2Alberta Health Services, Edmonton, AB, Canada

    *Purpose: Machine perfusion for preservation of liver grafts before transplantation has risen in prominence over the past decade. Normothermic machine perfusion (NMP), in particular, has…
  • 2022 American Transplant Congress

    Ex Vivo Modification of Vascular Allografts Using Immunosuppressive and Anti-Inflammatory Polymers Prevent Rejection via Localized Immunosuppression

    H. D. Luo1, E. M. Siren1, W. Enns2, L. Sim1, C. Du1, S. G. Withers1, J. Choy3, J. N. Kizhakkedathu1

    1The University of British Columbia, Vancouver, BC, Canada, 2Simon Fraser University, Burnaby, BC, Canada, 3Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada

    *Purpose: Classical immunosuppressants lead to systemic immune shutdown, though necessary to mediate transplant rejection, it may lead to various complications. To reduce off-target immunosuppression while…
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