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American Transplant Congress abstracts

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Articles tagged "Pediatric"

  • 2022 American Transplant Congress

    Baseline Trends in Tacrolimus Intrapatient Variability in Pediatric and Young Adult Kidney Transplant Recipients

    K. Piburn1, L. Maestretti2, M. V. Patton2, A. M. McGrath2, O. S. Indridason3, A. Chaudhuri1, P. Grimm1, V. Sigurjonsdottir1

    1Pediatric Nephrology, Stanford University, Palo Alto, CA, 2Pediatric Kidney Transplant, Lucile Packard Children's Hospital, Palo Alto, CA, 3Division of Nephrology, Landspitali – the National University Hospital of Iceland, Reykjavik, Iceland

    *Purpose: High tacrolimus intrapatient variability (IPV) is a known risk factor for poor graft outcomes in kidney transplantation. Baseline trends in tacrolimus IPV have not…
  • 2022 American Transplant Congress

    Long Term Analysis of Pediatric En-Bloc Kidney Transplantation: A Single Center Experience

    H. H. Patel1, P. Di Cocco2, J. Almario2, A. Fratti2, S. Akshelyan2, E. Benedetti2, I. Tzvetanov2, M. Spaggiari2

    1University of Missouri-Kansas City School of Medicine, Kansas City, MO, 2University of Illinois at Chicago, Chicago, IL

    *Purpose: Pediatric en-bloc kidney transplantations for adult recipients are uncommonly performed due to unique donor characteristics, the technical challenge of the operation, and potential surgical…
  • 2022 American Transplant Congress

    Non-HLA Antibodies to G Protein-Coupled Receptors and Allograft Survival in Pediatric Kidney Transplant Recipients: Short- and Long-Term Outcomes

    M. Pearl1, L. Chen1, P. Weng1, E. T. Chambers2, E. F. Reed3

    1UCLA, Los Angeles, CA, 2Pediatrics, Duke University, Durham, NC, 3Univ of California LA, Los Angeles, CA

    *Purpose: We have recently shown that the non-HLA antibodies to angiotensin II type 1 receptor (AT1R-Ab) and endothelin-1 type A receptor (ETAR-Ab) are prevalent and…
  • 2022 American Transplant Congress

    Outcomes in Pediatric Intestinal Retransplantation

    E. J. Lee1, G. Mazariegos1, K. Soltys1, G. Bond1, A. Ganoza1, J. Rudolph2, S. Horslen2, R. Sindhi1, A. Khanna1

    1Transplant Surgery, UPMC, Pittsburgh, PA, 2Division of Gastroenterology, Hepatology and Nutrition,, UPMC, Pittsburgh, PA

    *Purpose: Historically, intestinal retransplantation (Re-ITx) has been associated with high morbidity and mortality.*Methods: Retrospective chart review of patients who underwent Re-ITx at our institution between…
  • 2022 American Transplant Congress

    Collaboration for Successful Transition to Adult Care in Liver Transplant: Early Outcomes of a Structured Program with Youth Engagement

    B. Kosmach-Park1, J. Kilpatrick2, A. Algeo1, K. Jones1, L. Remaley1, N. Elazzazy2, N. Jonassaint3, G. Mazariegos1

    1Transplant Surgery, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, 2Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, 3Department of Medicine and Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA

    *Purpose: To effectively transition youth to adult hepatology through a structured program and developed partnerships while promoting and maintaining optimal outcomes.*Methods: The pediatric and adult…
  • 2022 American Transplant Congress

    Single-Cell CyTOF Profiling of Pediatric Immune Responses to Organ Transplantation Reveals a Novel Subpopulation of T Cells Significantly Correlating with Graft Health

    M. Rao1, M. Amouzgar1, J. T. Harden1, M. Lapasaran1, A. Trickey1, B. Armstrong2, J. Odim3, T. Debnam3, C. Esquivel1, S. C. Bendall1, O. Martinez1, S. M. Krams1

    1Stanford University, Palo Alto, CA, 2Rho, Durham, NC, 3National Institutes of Health, Bethesda, MD

    *Purpose: Solid organ transplant is lifesaving for children with end-stage heart, liver, or kidney disease. Protection of the transplanted organ from rejection requires long-standing immunosuppression.…
  • 2022 American Transplant Congress

    Why and How We Do Native Nephrectomy in Low Weight Pediatric Kidney Transplantation Patients

    N. Celik1, B. Akyollu1, E. Arpali1, N. Akinci2, I. Bilge2, B. Kocak1

    1Division of Organ Transplantation, Koc University Hospital, Istanbul, Turkey, 2Division of Pediatric Nephrology, Koc University Hospital, Istanbul, Turkey

    *Purpose: There is no consensus about optimal timing for native nephrectomy according to the primary indication of kidney transplantation (KTx) especially in pediatric population and…
  • 2022 American Transplant Congress

    Disruption of B Cell Population is Associated with Increased Infections in Pediatric Transplant Recipients

    B. Geng, L. Loop, C. Anterasian, D. Mortazavi, J. Kitsen, C. Collins, K. Newton, E. Ingulli

    Pediatrics, UCSD Rady Children's, San Diego, CA

    *Purpose: Solid-organ transplant recipients are placed on long-term immunosuppression, preventing graft rejection but increasing the risk of infection. Pediatric transplant recipients are at increased risk…
  • 2022 American Transplant Congress

    Surveillance of Donor-Derived Cell-Free DNA Throughout Treatment of Acute Rejection in Pediatric Renal Transplant Recipients

    K. A. Klein1, E. L. Kincaide1, M. Fei2, A. M. Bell2, M. Y. Arar3, D. Ranch3

    1Pharmacotherapy Education and Research Center, UT Health San Antonio, San Antonio, TX, 2CareDx, Inc., Brisbane, CA, 3Long School of Medicine, UT Health San Antonio, San Antonio, TX

    *Purpose: Donor-derived cell-free DNA (dd-cfDNA) is a dynamic plasma biomarker for allograft rejection with limited data in pediatric renal transplant recipients and few reports describing…
  • 2022 American Transplant Congress

    Pediatric Acute Liver Failure: Patient Factors Associated with Higher Mortality

    J. Ascher Bartlett1, C. Weaver1, S. Barhouma2, L. Houshmand2, B. Rocque2, K. Etesami2, R. Kohli1, J. Emamaullee2

    1Children's Hospital Los Angeles, Los Angeles, CA, 2University of Southern California, Los Angeles, CA

    *Purpose: Pediatric acute liver failure (PALF) is characterized by sudden onset deteriorating liver function, progressive coagulopathy, and hepatic encephalopathy in previously healthy children. The clinical…
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