Articles tagged "Pediatric"

2016 American Transplant Congress
The Impact of Thromboelastography on Resuscitation in Pediatric Liver Transplantation.
K. Gonzalez,¹ K. Curiel,¹ B. Dalton,¹ V. Fioravanti,¹ W. Andrews,¹ B. Wicklund,² R. Hendrickson.¹
¹Department of Pediatric Surgery, Children's Mercy Hospital, Kansas City, MO; ²Department of Hematology, Children's Mercy Hospital, Kansas City, MO.
Introduction: Thromboelastography (TEG) directs effective resuscitation in adult surgical and trauma patients. There is little data on TEG use in pediatrics. In 2011 we began…
2016 American Transplant Congress
Outcomes of Pediatric en Bloc Kidney (PeB) Grafts After Loss of a Single Kidney.
C. Santhanakrishnan, R. Perez, J. McVicar, J. Sageshima, C. Troppmannn.
Division of Transplantation, Dept of Surgery, Univ of Calif Davis Medical Center, Sacramento, CA.
Background: Transplantation (Tx) of PeB kidney grafts has been shown to result in good long-term outcomes. However, the fate of PeB grafts that suffer loss…
2016 American Transplant Congress
Racial Differences Amongst Infants Undergoing Intestine Transplants.
K. Khan, C. Desai, S. Kaufman, R. Girlanda, J. Hawksworth, A. Kroemer, T. Fishbein, C. Matsumoto.
Transplant Institute, MedStar Geogetown University Hospital, Washington, DC.
BackgroundIt is known that the demographics of the United States are changing because of immigration and increased birth rates in non-white populations. Here we examine…
2016 American Transplant Congress
Genomic-Derived Markers to Identify Calcineurin Inhibitor Nephrotoxicity in Pediatric Kidney Transplant Recipients.
E. Rhone,¹ R. Gehrau,² S. Bontha,² P. Walker,³ C. Dumur,⁴ D. Maluf,² V. Mas.²
¹Pediatrics, University of Virginia, Charlottesville, VA; ²Surgery, University of Virginia, Charlottesville, VA; ³Nephropath, Little Rock, AR; ⁴Pathology, Virginia Commonwealth University, Richmond, VA.
Background:Calcineurin inhibitor nephrotoxicity (CNIT) is a well-known contributor to chronic allograft dysfunction in kidney transplant recipients (KTRs). Pediatric KTRs are particularly at risk given their…
2016 American Transplant Congress
The Heterogenous Genomic Landscape of Unresectable Hepatoblastoma Requiring Liver Transplantation: Prognostic Implications.
M. Ningappa, B. Higgs, S. Ranganathan, C. Ashokkumar, R. Sindhi.
Surgery, Children's Hospital of Pittsburgh of UPMC and University of Pittsburgh, Pittsburgh, PA.
Background: Hepatoblastoma, the most common pediatric liver malignancy, is cured by chemotherapy and surgical resection. Locally invasive/multifocal tumors require liver transplantation (LTx). A unique tumor…
2016 American Transplant Congress
Conversion from Tacrolimus (TAC) to Sirolimus (SLR)-Based Immunosuppression in Pediatric Patients Who Underwent Liver Transplantation for Unresectable Hepatoblastoma – 2 Year Follow-Up.
R. Hendrickson,¹ W. Andrews,¹ M. Davis,¹ R. Cisneros,¹ R. Fischer,² J. Daniel.²
¹Pediatric/Transplant Surgery, Children's Mercy Hospitals and Clinics, Kansas City, MO; ²Hepatology, Children's Mercy Hospitals and Clinics, Kansas City, MO.
Introduction: The appropriate use of Sirolimus (SRL) immunosuppression in pediatric liver transplantation has yet to be clearly defined. Even though Tacrolimus (TAC) is commonly used…
2016 American Transplant Congress
Are We Refusing Good Organs? Outcomes of Ventilator Management of Sub-Optimal Lung Donors.
B. Scully,¹ D. Horne,¹ J. Heinle,¹ E. McKenzie,¹ K. Hosek,² W. Zhang,² G. Mallory,³ E. Melicoff.³
¹Congenital Heart Surgery, Texas Children's Hospital, Houston, TX; ²Outcomes and Impact Services, Texas Children's Hospital, Houston, TX; ³Pulmonology, Texas Children's Hospital, Houston, TX.
PurposeOptimizing donor lung function is essential for organ acceptance and successful lung transplantation (LTx). We hypothesized that ventilator management of sub-optimal donor lungs, PaO2<300 mmHg,…
2016 American Transplant Congress
Living Related Small Bowel Transplantation in Children, a Single-Center Experience – Growth, Development and Quality of Life 10 Years After Transplant.
S. Garcia Aroz,¹ I. Tzvetanov,¹ E. Hetterman,² J. Hoonbae,¹ M. Spaggiari,¹ J. Oberholzer,¹ G. Testa,³ E. John,⁴ E. Benedetti.¹
¹Surgery, University of Illinois, Chicago, IL; ²Pharmacy, University of Illinois, Chivago, IL; ³Surgery, Baylor Medical Center, Dallas, TX; ⁴Pediatrics, University of Illinois, Chicago, IL.
Summary Background: Pediatric patients with irreversible intestinal failure present multiple challenges due to their young ages and their associated growth needs. We have previously published…
2016 American Transplant Congress
Impact of Everolimus and Low-Dose Ciclosporin on Cytomegalovirus Replication and Disease in Pediatric Renal Transplantation.
B. Höcker,¹ S. Zencke,¹ L. Pape,² K. Krupka,¹ L. Kösters,¹ A. Fichtner,¹ L. Dello Strologo,² I. Guzzo,² R. Topaloglu,² B. Kranz,² J. König,² M. Bald,² N. Webb,² A. Noyan,² H. Dursun,² S. Marks,² Z. Ozcakar,² F. Thiel,² H. Billing,² M. Pohl,² H. Fehrenbach,² P. Schnitzler,¹ T. Bruckner,¹ L. Weber,² R. Feneberg,² T. Ahlenstiehl-Grunow,² B. Tönshoff.¹
¹University Children's Hospital, Heidelberg, Germany; ²Certain Research Community, Germany, Italy, Turkey, United Kingdom.
Purpose: Preclinical studies indicate an anti-cytomegalovirus (CMV) activity of the mammalian target of rapamycin inhibitor (mTORi) everolimus (EVR), but data in pediatric renal transplant recipients…
2016 American Transplant Congress
Pediatric Liver Transplant Exception Request Narratives – How Do We Justify Requests?
H. Braun,³ S. Rhee,¹ J. Dodge,² J. Roberts,² E. Perito.¹
¹Pediatrics, University of California-San Francisco, San Francisco, CA; ²Surgery, University of California-San Francisco, San Francisco, CA; ³School of Medicine, University of California-San Francisco, San Francisco, CA.
Purpose: Over 50% of pediatric liver transplant (LT) candidates receive exceptions to increase PELD/MELD; more than [frac12] are non-standard exception requests (NSER) based on narrative…