2017 American Transplant Congress
Personalizing Immunosuppression with Molecular Phenotyping in Pediatric Liver Transplantation.
Pediatric Abdominal Transplant, Children's Hospital of Pittsburgh of UPMC, Pittsburgh
Background: Optimizing immunosuppression requires selecting an agent which can inhibit the dominant anti-rejection mechanism in individual children with liver transplantation (LTx). Extended use of steroids,…2017 American Transplant Congress
Describing the Effects of the Antibiotic Regimen Immediate Post Multi-Visceral Transplant in the Pediatric Population on the Time to First Serious Bacterial Infection.
This study is designed to elucidate the effect a tailored antibiotic regimen administered immediately post multi visceral transplantation may have on the duration until first…2017 American Transplant Congress
Rapid Regression of Xanthomata After Orthotopic Liver Tranplantation for Alagille Syndrome.
Arteriohepatic dysplasia, or Alagille syndrome, is a genetic disorder characterized by chronic cholestasis in the setting of multiple congenital abnormalities of different organ systems, including…2017 American Transplant Congress
Long Term Outcomes of Adult Kidney Transplants from Small Single Pediatric Donors Are Equivalent to Standard Criteria Donors.
Surgery, Weill Cornell Medicine, New York, NY
PurposeWe analyzed long term outcomes of adult kidney transplant recipients from single pediatric donors at a large volume center.MethodsA retrospective review of 90 adult kidney…2017 American Transplant Congress
Small Pediatric Donor Kidney Transplantation in Pediatric Recipients.
Kidneys from small pediatric donors (age <5 years, weight <21 kg) may be a means to increase the donor pool for pediatric recipients. Transplantation of…2017 American Transplant Congress
Efficacy and Safety of Everolimus with Reduced Tacrolimus or Cyclosporine in Pediatric Liver Transplant Recipients: 12-Month Results from H2305 Study.
1H2305 Study Group, St Louis; 2Novartis Pharma AG, Basel, Switzerland
Purpose: Everolimus (EVR) facilitated calcineurin inhibitor (CNI) reduction has shown improved renal function (RF) without compromising efficacy in adult liver transplant recipients (LTxR). Here we…2017 American Transplant Congress
Heterotopic Auxiliary Liver Transplantation(ALTx) – Revisited.
University of Minnesota, Minneapolis
Background:Although, ALTx for acute liver failure(ALF) has been described over 30yrs ago, utilization of operation has been limited. Benefit of operation is to provide bridge…2017 American Transplant Congress
Digital Image Analysis of Pediatric Liver Allograft Biopsies Correlates with METAVIR Fibrosis Score.
1Children's Mercy Hospital, Kansas City, MO; 2University of Kansas Medical Center, Kansas City, KS
Background: Serial surveillance biopsies demonstrate post-transplant inflammation and fibrosis in long-surviving pediatric liver allografts. These changes can ultimately lead to cirrhosis and graft failure. However,…2017 American Transplant Congress
Renal Transplantation to the Extraperitoneal Cavity in Children Weighing Less Than 15 kg Can Be Performed Safely.
INTRODUCTION AND OBJECTIVES: Pediatric kidney transplantation is associated with various surgical complications due to the complexity of technique and often fragile condition of end-stage renal…2017 American Transplant Congress
Rapamycin Maintenance Therapy in Pediatric Liver Transplant Recipients Associated with Trend Toward Decreasing Th2 Cytokine Levels Compared to Tacrolimus Therapy.
1Children's Mercy Hospital, Kansas City, MO; 2University of Kansas Medical Center, Kansas City, KS
Background: Maintenance immunosuppression after liver transplantation with tacrolimus (TAC) may have progressive fibrosis on serial allograft biopsies. mTOR inhibitors such as rapamycin (RAPA) may abrogate…
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