2017 American Transplant Congress
EBV-Specific CD8+ T Cells from Pediatric Thoracic vs Abdominal Transplant Recipients Are Shaped Differently by the Chronic EBV Loads with Potential Impact on the Risk of PTLD.
Background: EBV infection and post-transplant lymphoproliferative disorders (PTLD) are life-threatening complications of pediatric solid organ transplantation (Tx). Chronic high EBV viral load (HVL) carriers have…2017 American Transplant Congress
Acute Renal Replacement Therapy in Pediatric Liver Transplantation: A Predictor of Increased Risk.
1Surgery, UCLA, Los Angeles, CA; 2Pediatric Gastroenterology, UCLA, Los Angeles, CA
BackgroundAmong pediatric patients (≤18 yrs) awaiting liver transplantation (LT), limited data exist on the prognostic significance of acute (<90d) renal replacement therapy (RRT) prior to…2017 American Transplant Congress
Superior Long-Term Hypertension Management in Pediatric Kidney Transplant Recipients with Bilateral Native Nephrectomies.
Introduction: Native nephrectomy in pediatric kidney transplant recipients is performed for congenital anomalies, proteinuria, intractable hypertension, malignancy, and chronic infection. Post-transplant hypertension requiring medical management…2017 American Transplant Congress
Impairment of Glucose Tolerance After Pediatric Kidney Transplant Is Associated with Worse Systemic Insulin Sensitivity Rather Than Fall in Insulin Secretion.
Renal and Genitourinary Surgery, Hokkaido University, Sapporo, Hokkaido, Japan
Introduction and Objective: Tacrolimus and steroid are considered to affect insulin secretion and insulin sensitivity, respectively, resulting in worse glucose tolerance after pediatric kidney transplant…2017 American Transplant Congress
Clinical and Histopathologic Features of Antibody Mediated Rejection (ABMR) in Highly Sensitized (HS) vs Non-Sensitized (NS) Pediatric Renal Transplant Recipients.
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
Background: The presence of preformed donor-specific antibody (pDSA) in HS pts and development of de-novo DSA (dnDSA) in NS patients are risk factors for ABMR.…2017 American Transplant Congress
Efficacy and Safety of Everolimus with Reduced-Exposure Tacrolimus and Corticosteroid Withdrawal in De Novo Pediatric Renal Transplant Recipients: 12-Month Results from the CRADLE Study.
PURPOSE: We present 12-month (M) results from the CRADLE study (NCT01544491) that assessed efficacy and safety of everolimus (EVR) with reduced-exposure tacrolimus (rTAC) and early…2017 American Transplant Congress
Long-Term Pediatric Live-Donor Liver Transplantation Survivors: Patient and Allograft Outcomes.
Aim: To determine the patient and allograft outcomes at 5 years after pediatric live-donor liver transplantation (LDLT).Methods: Children with a minimum of 5-year survival post-transplantation…2017 American Transplant Congress
Ambulatory Blood Pressure Monitoring Detects High Prevalence of Hypertension in Recipients of Non-Renal Transplants.
Long-term survival after pediatric non-renal organ and stem cell transplantation (tx) has become increasingly better. The optimal post-transplant care therefore goes beyond organ-specific issues and…2017 American Transplant Congress
Rates of Lost to Follow-Up Among Pediatric Heart, Kidney, and Liver Transplant Recipients.
Background. Pediatric transplant recipients are typically transitioned to adult transplant programs for post-transplant care after age 18. For pediatric kidney (KI) recipients transitioning to adult…2017 American Transplant Congress
Longitudinal Study of Donor Specific Antibodies in a Pediatric Kidney Transplant Population; Response to Optimization of Anti-Proliferative Therapy.
Children's Hospital Colorado, Aurora, CO
In 2015 we implemented surveillance donor-specific antibody (DSA) monitoring in our pediatric kidney transplant recipients (pKTR); we found that in stable pKTRs (i.e. no changes…
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