2018 American Transplant Congress
Predicting Pediatric Liver Transplant Rejection with Peripheral Blood Leukocyte (PBL) Transcripts-Considerations and Design Limitations
Pediatric Abdominal Transplant, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.
Background: Optimizing immunosuppression requires individualized rejection-risk assessment in children with liver transplantation (LTx). PBL transcripts are a desirable non-invasive solution. Purpose: To characterize PBL transcriptome…2018 American Transplant Congress
Preparation for Transfer to Adult Kidney Transplant Care: Impacts of Providing Written Guidance
Objective: Survey youth and parents in a pediatric kidney transplant clinic with the following aims: 1) Compare pre- and post-intervention experiences with the transition process;…2018 American Transplant Congress
Programmed Cell Death Ligand 1 (PD-L1) Expression is Associated with Subtypes of Post-Transplant Lymphoproliferative Disorders (PTLD)
Introduction: PD-L1 expression on select tumor cells engages the PD-1 receptor on T cells, inhibiting anti-tumor immune responses. PD-L1 has been detected in cases of…2018 American Transplant Congress
Genome-Wide Association Study Assessing Risk of Rejection in Pediatric Transplant Recipients
Background: Rejection risk varies after solid organ transplantation (SOT). We explored genomic variants associated with susceptibility to graft rejection.Methods: SOTs enrolled in a multicenter prospective…2018 American Transplant Congress
Promoting Medication Adherence from the Perspectives of Teen and Young Adult Kidney Recipients, Parents and Health Care Professionals
1University of Pittsburgh, Pittsburgh, PA; 2MUHC, McGill, Montreal, QC, Canada.
Purpose: The Teen Adherence in KidnEy Transplant – Improving Tracking to Optimize Outcomes (TAKE-IT TOO) study was designed to adapt the efficacious Take-IT intervention for…2018 American Transplant Congress
A Research-Informed Framework for a Medication Adherence Intervention to Support Transition of Adolescent Kidney Recipients to Independent Medication-Taking
1University of Pittsburgh, Pittsburgh, PA; 2MUHC, McGill, Montreal, QC, Canada.
Purpose: Understand the needs and preferences of adolescent/young adult kidney recipients (12-24y), parents, and healthcare professionals (HCP), to inform adaptation of an efficacious adherence-promoting intervention…2018 American Transplant Congress
Donor-to-Recipient Weight Ratio is Significantly Associated with Hepatic Artery Thrombosis Following Pediatric Whole Liver Transplantation
Surgery, Boston Children's Hospital, Boston, MA.
Background: Hepatic artery thrombosis (HAT) following pediatric liver transplantation is associated with increased morbidity and risk of graft failure. In our clinical practice, we have…2018 American Transplant Congress
Clinical Outcomes, Care Needs and Adherence in Long Term Intestine Transplant Survivors ≥10 yrs
Background: Although survival has increased significantly for pediatric ITx recipients, continued graft surveillance and monitoring of clinical and psychosocial outcomes are essential. Purpose: Describe clinical…2018 American Transplant Congress
Deceased Pediatric Donor Livers: How Current Policy Drives Allocation and Transplantation
Background:The current liver allocation algorithm for livers from deceased pediatric (<18y; “pedi“) donors prioritizes adults listed locally/regionally over children listed nationally. We sought to understand…2018 American Transplant Congress
Amiodarone Use Increases Morbidity Not Mortality in Pediatric Heart Transplant Recipients
Pediatric Cardiology, St.Louis Children's Hospital, St. Louis, MO.
Background: Amiodarone is commonly used in pediatric and adult patients with end-stage heart failure and its use is associated with increased 1-year post-transplant mortality in…
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