2018 American Transplant Congress
Distribution of Biopsy Proven Acute Rejection in a Large Pediatric Kidney Transplant Program: A Four Year Experience
Introduction: Kidney biopsy is the gold standard for diagnosing rejection, transplant glomerulopathy, and other pathology after transplantation. We aimed to understand the distribution of Banff…2018 American Transplant Congress
Psychosocial Assessment of Candidates for Transplantation (PACT) Identifies Non-Adherence in Pediatric Kidney Transplantation
1School of Medicine, Duke University, Durham, NC; 2Pediatrics, Duke University, Durham, NC.
Background: We have demonstrated that overall pre-transplant Psychosocial Assessment of Candidates for Transplantation (PACT) scores can identify high risk pediatric kidney recipients. In this pilot…2018 American Transplant Congress
BK Polyomavirus (BKPyV)-Specific T Cells as a Diagnostic and Prognostic Marker for BKPyV-Infections after Pediatric Kidney Transplantation
After kidney transplantation (KTx) immunosuppressive therapy causes an impaired cellular immune defense resulting in an increased risk of BKPyV-nephropathy (BKPyVAN). Prognostic markers for the outcome…2018 American Transplant Congress
T cell Phenotypes Predict Infectious Risk in Transplanted Children
AIM: Current monitoring strategies do not adequately differentiate infection from complications such as allograft rejection (AR). We aimed to identify peripheral T cell phenotypes that…2018 American Transplant Congress
High Tacrolimus Variability is Associated with Worse Outcomes in Pediatric Renal Transplant Recipients
Montefiore Medical Center, Bronx, NY.
Background: Subtherapeutic tacrolimus trough concentrations are associated with donor specific antibody (DSA), acute rejection and shortened graft survival. The role of intrapatient variability in tacrolimus…2018 American Transplant Congress
Age Difference between Donor and Recipient Predisposes to Early Interstitial Fibrosis and Tubular Atrophy in Pediatric Kidney Transplantation
Pediatric Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA.
Introduction: Previous studies in adult kidney transplant recipients (KTRs) have shown that an increased age difference between donor and recipient increases the risk of arterial…2018 American Transplant Congress
Pediatric Kidney Allograft Outcomes Following Identification of Transplant Glomerulopathy by Electron Microscopy
LSU Health Sciences Center, New Orleans, LA.
We have previously shown that electron microscopy (EM) can facilitate early diagnosis of transplant glomerulopathy (TG) in pediatric kidney transplant biopsies (Bx) with normal light…2018 American Transplant Congress
Transplant Cost Reduction in a Developing Country: “The Case of Guatemala”
Background: Guatemala, south-west of Mexico has a population of approximately 16 million people of which 60% are younger than 20 years. As any other developing…2018 American Transplant Congress
Improved Renal Allograft Survival for Pre-Emptive Paediatric Renal Transplant Recipients in the United Kingdom
OBJECTIVESThe aim of this study was to investigate whether being on dialysis at the time of renal transplantation affected renal allograft survival in paediatric renal…2018 American Transplant Congress
Immune Phenotyping in a Pediatric Multicenter Transplant Study: Suitability of a Pre-Formulated Dry Antibody Panel System
Background:Flow cytometric immune-phenotyping is influenced by cryopreservation and inter-laboratory variability limiting comparability in multi center studies. The Duraclone™ system (DC) provides optimized pre-mixed dry antibody…
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