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Articles tagged "Pediatric"

  • 2018 American Transplant Congress

    Genome-Wide Association Study Assessing Risk of Rejection in Pediatric Transplant Recipients

    T. Papaz,1 S. Min,1 O. Lee,1 T. Blydt-Hansen,3 U. Allen,1 Y. Avitzur,1 P. Birk,2 B. Foster,4 H. Grasemann,1 L. Hamiwka,5 R. Parekh,1 V. Phan,6 S. Urschel,7 S. Mital.1

    1SickKids Hospital, Toronto, ON, Canada; 2Winnipeg Children's Hospital, Winnipeg, MB, Canada; 3BC Children's Hospital, Vancouver, BC, Canada; 4Montreal Children's Hospital, Montreal, QC, Canada; 5Alberta Children's Hospital, Calgary, AB, Canada; 6CHU Sainte Justines, Montreal, QC, Canada; 7Stollery Children's Hospital, Edmonton, AB, Canada.

    Background: Rejection risk varies after solid organ transplantation (SOT). We explored genomic variants associated with susceptibility to graft rejection.Methods: SOTs enrolled in a multicenter prospective…
  • 2018 American Transplant Congress

    Promoting Medication Adherence from the Perspectives of Teen and Young Adult Kidney Recipients, Parents and Health Care Professionals

    C. Nguyen,1 M. Dew,1 A. DeVito Dabbs,1 T. Irizarry,1 M. McNulty,1 B. Foster.2

    1University of Pittsburgh, Pittsburgh, PA; 2MUHC, McGill, Montreal, QC, Canada.

    Purpose: The Teen Adherence in KidnEy Transplant – Improving Tracking to Optimize Outcomes (TAKE-IT TOO) study was designed to adapt the efficacious Take-IT intervention for…
  • 2018 American Transplant Congress

    A Research-Informed Framework for a Medication Adherence Intervention to Support Transition of Adolescent Kidney Recipients to Independent Medication-Taking

    T. Irizarry,1 A. DeVito Dabbs,1 M. Dew,1 B. Foster.2

    1University of Pittsburgh, Pittsburgh, PA; 2MUHC, McGill, Montreal, QC, Canada.

    Purpose: Understand the needs and preferences of adolescent/young adult kidney recipients (12-24y), parents, and healthcare professionals (HCP), to inform adaptation of an efficacious adherence-promoting intervention…
  • 2018 American Transplant Congress

    Donor-to-Recipient Weight Ratio is Significantly Associated with Hepatic Artery Thrombosis Following Pediatric Whole Liver Transplantation

    S. Kim, G. Ramos-Gonzalez, Z. Labib, H. Kim, K. Vakili.

    Surgery, Boston Children's Hospital, Boston, MA.

    Background: Hepatic artery thrombosis (HAT) following pediatric liver transplantation is associated with increased morbidity and risk of graft failure. In our clinical practice, we have…
  • 2018 American Transplant Congress

    Clinical Outcomes, Care Needs and Adherence in Long Term Intestine Transplant Survivors ≥10 yrs

    B. Kosmach-Park,1 G. Mazariegos.2

    1Transplant Surgery, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

    Background: Although survival has increased significantly for pediatric ITx recipients, continued graft surveillance and monitoring of clinical and psychosocial outcomes are essential. Purpose: Describe clinical…
  • 2018 American Transplant Congress

    Deceased Pediatric Donor Livers: How Current Policy Drives Allocation and Transplantation

    E. Hsu,2 J. Ge,1 J. Bucuvalas,3 J. Lai.1

    1UC-San Francisco, San Francisco, CA; 2Seattle Children's Hospital, Seattle, WA; 3Cincinnati Children's Hospital, Cincinnati, OH; 4University of California San Francisco, San Francisco, CA.

    Background:The current liver allocation algorithm for livers from deceased pediatric (<18y; “pedi“) donors prioritizes adults listed locally/regionally over children listed nationally. We sought to understand…
  • 2018 American Transplant Congress

    Amiodarone Use Increases Morbidity Not Mortality in Pediatric Heart Transplant Recipients

    S. Amdani, A. Dalal, K. Simpson, J. Scheel, A. Abarbanell, P. Eghtesady, C. Canter, C. Castleberry.

    Pediatric Cardiology, St.Louis Children's Hospital, St. Louis, MO.

    Background: Amiodarone is commonly used in pediatric and adult patients with end-stage heart failure and its use is associated with increased 1-year post-transplant mortality in…
  • 2018 American Transplant Congress

    Creatinine Monitoring by Remote Blood Spot Testing in Pediatric Kidney Transplant Recipients

    J. Dickerson,1 K. Jacot,2 M. Sinkey,2 J. Smith.3

    1Laboratory Medicine, Seattle Children's, Seattle; 2Transplant, Seattle Children's, Seattle; 3Pediatrics, University of Washington, Seattle.

    Introduction: Pediatric kidney transplant patients are monitored frequently with laboratory testing to assess kidney transplant function and to optimize therapeutic drug levels. Challenges to timely…
  • 2018 American Transplant Congress

    Recurrence of Focal Segmental Glomerulosclerosis (FSGS) and Response to Prolonged Plasmapheresis Therapy: A Single Center Pediatric Experience

    A. Bobrowski, D. Matossian.

    Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern Feinberg School of Medicine, Chicago, IL.

    FSGS is the most common glomerular cause of ESKD in pediatric patients. The risk of recurrence after kidney transplant (KT) is 30-60%, and half of…
  • 2018 American Transplant Congress

    Chronic Rejection: Risk Factors, Clinical Presentation and Outcome in Pediatric Liver Transplant Recipients: A Single Center Experience

    T. Miloh, A. Cheng, D. Schady, R. Himes, K. Mysore, K. Hosek, J. Goss.

    Texas Children's Hospital, Baylor College of Medicine, Houston, TX.

    Chronic rejection (CR) is the leading indication for long term graft loss. We discuss our centers' experience with CR diagnosis and management. Method: Electronic medical…
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