2018 American Transplant Congress
Long Term Histologic Allograft Health is Preserved Despite Rejection during Protocolized Immunosuppression Withdrawal (ISW) in Stable Pediatric Liver Transplant Recipients
Background: Long term allograft health after rejection during ISW has not been previously assessed. We compare baseline and 4yr graft histology of 20 rejectors in…2018 American Transplant Congress
The Impact of the Influenza Vaccine on Pediatric Kidney Transplant Outcomes
The influenza vaccine has been associated with de novo DSA and rejection in adult kidney recipients. This risk has not been adequately assessed in pediatric…2018 American Transplant Congress
Large Volume Intraoperative Fluid Use in Small (<20kg) Renal Recipients is Safe
INTRODUCTION: With advances in surgical and medical transplantation, progressively younger children are being transplanted. There is no consensus and little evidence on the optimal intraoperative…2018 American Transplant Congress
Distribution of Biopsy Proven Acute Rejection in a Large Pediatric Kidney Transplant Program: A Four Year Experience
Introduction: Kidney biopsy is the gold standard for diagnosing rejection, transplant glomerulopathy, and other pathology after transplantation. We aimed to understand the distribution of Banff…2018 American Transplant Congress
Psychosocial Assessment of Candidates for Transplantation (PACT) Identifies Non-Adherence in Pediatric Kidney Transplantation
1School of Medicine, Duke University, Durham, NC; 2Pediatrics, Duke University, Durham, NC.
Background: We have demonstrated that overall pre-transplant Psychosocial Assessment of Candidates for Transplantation (PACT) scores can identify high risk pediatric kidney recipients. In this pilot…2018 American Transplant Congress
BK Polyomavirus (BKPyV)-Specific T Cells as a Diagnostic and Prognostic Marker for BKPyV-Infections after Pediatric Kidney Transplantation
After kidney transplantation (KTx) immunosuppressive therapy causes an impaired cellular immune defense resulting in an increased risk of BKPyV-nephropathy (BKPyVAN). Prognostic markers for the outcome…2018 American Transplant Congress
T cell Phenotypes Predict Infectious Risk in Transplanted Children
AIM: Current monitoring strategies do not adequately differentiate infection from complications such as allograft rejection (AR). We aimed to identify peripheral T cell phenotypes that…2018 American Transplant Congress
High Tacrolimus Variability is Associated with Worse Outcomes in Pediatric Renal Transplant Recipients
Montefiore Medical Center, Bronx, NY.
Background: Subtherapeutic tacrolimus trough concentrations are associated with donor specific antibody (DSA), acute rejection and shortened graft survival. The role of intrapatient variability in tacrolimus…2018 American Transplant Congress
Age Difference between Donor and Recipient Predisposes to Early Interstitial Fibrosis and Tubular Atrophy in Pediatric Kidney Transplantation
Pediatric Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA.
Introduction: Previous studies in adult kidney transplant recipients (KTRs) have shown that an increased age difference between donor and recipient increases the risk of arterial…2018 American Transplant Congress
Pediatric Kidney Allograft Outcomes Following Identification of Transplant Glomerulopathy by Electron Microscopy
LSU Health Sciences Center, New Orleans, LA.
We have previously shown that electron microscopy (EM) can facilitate early diagnosis of transplant glomerulopathy (TG) in pediatric kidney transplant biopsies (Bx) with normal light…
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