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Articles tagged "Pediatric"

  • 2019 American Transplant Congress

    Efficacy and Safety of Everolimus in Pediatric Renal Transplantation

    T. Sandes-Freitas1, B. Pantoja2, M. Custódio2, A. Goersch Silva3, R. Costa2, M. Sales3, R. Esmeraldo3

    1Hospital Geral de Fortaleza / Federal University of Ceara, Fortaleza, Brazil, 2Federal University of Ceará, Fortaleza, Brazil, 3Hospital Geral de Fortaleza, Fortaleza, Brazil

    *Purpose: There are scarce evidence on the efficacy and safety of everolimus (EVR)-based regimens in pediatric kidney transplantation (KT).*Methods: This single center retrospective cohort analyzed…
  • 2019 American Transplant Congress

    Metabolic Liver Transplantation – Can We Afford It?

    N. Yazigi1, W. Fujiwara2

    1Transplant Institute, MedStar Georgetown University Hospital, Washigton, DC, 2Georgetown University Medical School, Washigton, DC

    *Purpose: Despite major improvement in medical and nutritional care of pediatric patients suffering from intoxication inherited metabolic disorders, their long term outcomes remain guarded. Liver…
  • 2019 American Transplant Congress

    Impact of the Pediatric End-Stage Liver Disease Growth Failure Threshold on Waitlist Mortality in Children Awaiting Liver Transplant

    S. M. Swenson, J. P. Roberts, S. Rhee, E. R. Perito

    University of California, San Francisco, San Francisco, CA

    *Purpose: To examine the impact on waitlist mortality of Pediatric End-Stage Liver Disease (PELD)’s incorporation of growth failure (GF) as a threshold variable—present or absent…
  • 2019 American Transplant Congress

    IgG4 Subclass Class 2 Donor Specific Antibody (DSA) is Associated with Subclinical Rejection in Stable Pediatric Liver Transplant (LT) Recipients with Normal Liver Tests

    A. Jackson1, S. Kanaparthi2, B. Burrell3, D. Lucas4, R. Vega4, A. J. Demetris5, S. Feng6

    1Surgery, Duke University, Durham, NC, 2The Immune Tolerance Network, Bethesda, MD, 3Immune Tolerance Network, Bethesda, MD, 4Medicine, Johns Hopkins University, Baltimore, MD, 5Pathology, University of Pittsburgh, Pittsburgh, PA, 6Surgery, University of California San Francisco, San Francisco, CA

    *Purpose: DSA is a known biomarker of allograft rejection, yet injury phenotype and potential differ across organs. Among pediatric LT recipients entering iWITH (NCT01638559), an…
  • 2019 American Transplant Congress

    Use of Marginal Liver Donors in Pediatric Transplantation: Diverse Profiles of Use in Major Transplant Centers

    C. S. Hwang1, A. Aqul2, A. Mufti3, S. Hanish1, D. Desai1, P. Vagefi1, M. MacConmara1

    1Surgery, UT Southwestern, Dallas, TX, 2Pediatrics, UT Southwestern, Dallas, TX, 3Medicine, UT Southwestern, Dallas, TX

    *Purpose: Pediatric liver transplantation is highly specialized only a small number of centers have consistent large volume experience. We tested the hypothesis that large volume…
  • 2019 American Transplant Congress

    Outcomes after Declining Increased Infectious Risk Kidney Offers for Pediatric Candidates in the United States

    M. Bowring, K. Jackson, H. Wasik, A. Neu, J. Garonzik-Wang, C. Durand, N. Desai, A. Massie, D. Segev

    Johns Hopkins University, Baltimore, MD

    *Purpose: Kidneys from donors at increased infectious risk for disease transmission (IRDs) confer substantial survival benefit in adults, yet the impact of IRDs in pediatric…
  • 2019 American Transplant Congress

    Are Protocol Biopsies Necessary for Pediatric Renal Transplant Recipients?

    E. Allred, E. Ingulli

    Pediatrics, UCSD, San Diego, CA

    *Purpose: Renal allograft survival indirectly correlates with acute rejection episodes. Subacute rejection is also associated with decreased graft survival. Protocol biopsies (bxs) have been implemented…
  • 2019 American Transplant Congress

    Repeat Liver Transplantation after Failed First Transplant in Childhood: Development of a Retransplant Risk Index

    M. Gupta1, M. Barry2, M. Levine3, K. Olthoff3, A. Shaked3, P. Abt3

    1University of Kentucky, Lexington, KY, 2University of California, San Francisco, San Francisco, CA, 3University of Pennsylvania, Philadelphia, PA

    *Purpose: Most morbidity and mortality after pediatric liver retransplantation (LRTx) occurs in the first 100 days. We studied factors associated with mortality and graft failure…
  • 2019 American Transplant Congress

    Pathologic Vascular Invasion Correlates with Worse Outcome in Hepatoblastoma Patients Treated with Liver Transplantation – A Hepatoblastoma Transplant Consortium Study

    T. H. Malik1, H. Zhu2, T. Ha3, S. Commander4, C. Trautz5, R. Sindhi5, S. Kim6, K. Vakili6, N. Vachharajani7, W. Chapman7, A. Griesemer8, M. Martinez8, J. A. Goss9, S. Vasudevan10

    1Baylor College of Medicine, Houston, TX, 2Texas Children's Hospital, Houston, TX, 3Department of Surgery, Baylor College of Medicine, Houston, TX, 4Department of Surgery, Duke University School of Medicine, Durham, NC, 5Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 6Department of Surgery, Boston Children's Hospital, Boston, MA, 7Department of Surgery, Washington University School of Medicine in St. Louis, St. Louis, MO, 8Department of Surgery, NewYork-Presbyterian Morgan Stanley Children's Hospital, New York, NY, 9Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX, 10Department of Pediatric Surgery, Texas Children's Hospital, Houston, TX

    *Purpose: Orthotopic liver transplant (OLTx) is the most common method to treat unresectable hepatoblastoma (HB) in children. There is limited data focusing on the outcomes…
  • 2019 American Transplant Congress

    Early Tacrolimus Trough Concentration Variability Could Predict Rejection in Pediatric Liver Transplantation: A Single-Center and Retrospective Research

    G. Gu, Q. Xia

    Renji Hospital, Shanghai, China

    *Purpose: With great development in immunosuppressive therapy, the long-term outcomes and survival time in patients who received solid organ transplantation have been improved remarkably. The…
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