Articles tagged "Pediatric"

2019 American Transplant Congress
Epitope-Based Matching in Pediatric Kidney Transplantation
C. Boussard¹, M. Ould Rabah², O. Boyer², M. Macher¹, J. Taupin³, J. Hogan⁴
¹Department of Pediatric Nephrology, Robert Debre hospital, APHP, Paris, France, ²Department of Pediatric Nephrology, Necker Enfants-Malades, APHP, Paris, France, ³Department of Immunology, Saint-Louis Hospital, APHP, Paris, France, ⁴Transplant Research Center, Department of Surgery, Emory University, ATLANTA, GA
*Purpose: Following the allocation of a transplant by the allocation system, each pediatric transplant team reviews the proposal and decides based on various criteria whether…
2019 American Transplant Congress
Utilization of Small Pediatric Donor Kidneys to Improve Access to Kidney Transplantation for Underappreciated Uremic Children in China
X. Su¹, W. Shang², L. Liu¹, Y. Feng², H. Zhang¹, J. Li¹, Q. Fu¹, X. Pang², G. Feng², C. Wang¹
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Kidney Transplantation Unit, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
*Purpose: We previously reported that children with end-stage renal disease had less chance to access to kidney transplantation from deceased donors in China. The number…
2019 American Transplant Congress
Ex Vivo Resection And Autologous Liver Transplantation As Management Concept For Extensive Malignancy
K. Bruestle¹, A. Griesemer², S. Lobritto², M. Martinez², J. Vittorio², D. Yamashiro², E. Bacha³, T. Kato²
¹Columbia Center for Translational Immunology, Columbia University, New York City, NY, ²Columbia Center for Liver Disease and Transplantation, Columbia University Medical Center, New York City, NY, ³Morgan Stanley Children's Hospital, Columbia University Medical Center, New York City, NY
*Purpose: Neuroblastomas are rare neural crest derived tumors which contribute disproportionally to childhood morbidity and mortality. Surgical resection remains standard treatment, however adequate resection is…
2019 American Transplant Congress
Increase in 48 Month Cumulative Acute Rejection Rates in the Most Recent Cohort: The 2018 Transplant Report of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS)
V. Dharnidharka¹, C. Cramer², A. Chua³, A. Moudgil⁴, K. Martz⁵, T. Blydt-Hansen⁶, J. Smith⁷, A. Neu, on Behalf of The NAPRTCS Investigators⁸
¹Washington University in St. Louis, Saint Louis, MO, ²Mayo Clinic, Rochester, MN, ³Duke University, Durham, NC, ⁴Children's National Medical Center, Washington, DC, ⁵Emmes Corporation, Rockville, MD, ⁶BC Children's Hospital, Vancouver, BC, ⁷Seattle Children's Hospital, Seattle, WA, ⁸Johns Hopkins University, Baltimore, MD
*Purpose: The NAPRTCS registry has collected data on children receiving kidney transplants in North America since 1987. The registry has served to document and influence…
2019 American Transplant Congress
Hepatoblastoma Tumors Requiring Liver Transplantation Manifest Dysregulated Ciliary, Autophagy and Cell Cycling Pathways in Systems Biology Analysis
T. Narayanan¹, M. Ningappa², B. W. Higgs², S. Subramaniam³, R. Sindhi²
¹Bioenginering, University of California, San Diego, CA, ²Childrens Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ³University of California, San Diego, CA
*Purpose: Liver transplantation (LT) can cure locally invasive, unresectable and chemo-resistant hepatoblastoma (HBL), an embryonal liver tumor of infancy. Post-LT immunosuppression enhances recurrence-risk despite chemotherapy.*Methods:…
2019 American Transplant Congress
Hit Me with Your Best Shot! Multidisciplinary Team Approach to Live Vaccination Administration in Pediatric Transplant Candidates
H. Corbo, K. Sprott, N. Pilch, K. Twombley, D. Taber
Medical University of South Carolina, Charleston, SC
*Purpose: Pre-transplant live vaccination rates are suboptimal in pediatric patients with end-stage organ disease. Ensuring live vaccine administration prior to transplant (txp) confers the best…
2019 American Transplant Congress
Long-Term Outcome and Surgical Complications Following Live-Donor Kidney Transplantation in Children Weighting Less Than 15 Kg: A Single Center Experience in Japan
Y. Aoki¹, H. Satoh², Z. Matsui², R. Hamada³, R. Harada³, M. Muramatsu⁴, Y. Hamasaki⁴, S. Shishido⁴
¹Urology and Kidney Transplantation, Tokyo Metropolitan Children’s Medical Center, Fuchu-shi, Tokyo, Japan, ²Urology and Kidney Transplantation, Tokyo Metropolitan Children’s Medical Center, Tokyo, Japan, ³Nephrology, Tokyo Metropolitan Children’s Medical Center, Tokyo, Japan, ⁴Nephrology, Toho University Faculty of Medicine, Tokyo, Japan
*Purpose: Kidney transplantation (KTx) is considered more technically challenging in small children, incurring a higher risk of potential surgical and vascular complications. Intraperitoneal approach of…
2019 American Transplant Congress
Incidence of De Novo Donor Specific Antibodies and Treatment Response for AMR in Pediatric Kidney Transplant Recipients
S. Gattis¹, R. Liverman¹, A. Serluco¹, J. Yin¹, H. C. Sullivan², R. A. Bray³, H. M. Gebel³, S. Jernigan⁴, R. George⁴, P. D. Winterberg⁴, R. Garro⁴
¹Children's Healthcare of Atlanta, Atlanta, GA, ²Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, ³Emory University Hospital, Atlanta, GA, ⁴Department of Pediatrics, Emory University School of Medicine, Atlanta, GA
*Purpose: Antibody-mediated rejection (AMR) is a significant complication in renal transplant patients. The aim of this study was to evaluate the incidence of de novo…
2019 American Transplant Congress
Epstein Barr Virus (EBV)-Specific T Cells as a Diagnostic Marker for the Individual EBV-Specific Immune Response after Pediatric Kidney Transplantation
T. Ahlenstiel-Grunow, L. Pape
Pediatric Nephrology, Hannover Medical School, Hannover, Germany
*Purpose: After transplantation immunosuppressive therapy causes an impaired cellular immune response resulting in an increased risk of EBV-associated complications, e.g. post-transplant lymphoproliferative disease (PTLD). Prognostic…
2019 American Transplant Congress
Long-Term Outcomes of Early Conversion to Sirolimus-Based Immunosuppression in Children with Living Donor Kidney Transplants
B. Stotter¹, S. Lui¹, E. Weller², L. Ganapathi¹, M. Ferguson¹, A. Traum¹, M. Somers¹, N. Rodig¹
¹Pediatrics, Boston Children's Hospital, Boston, MA, ²Biostatistics and Research Design Center, Boston Children's Hospital, Boston, MA
*Purpose: Following kidney transplantation (KTx), calcineurin inhibitor (CNI)-based maintenance immunosuppression (IS) can be associated with nephrotoxicity and other complications including viral infections and malignancy. Mammalian…