Articles tagged "Pediatric"

2020 American Transplant Congress
New Concept of Liver Transplatation in Pediatric Patient – Up Side Down Metod
P. Dubska, L. Janousek, J. Chlupac, M. Kocik, J. Fronek
Transplantation Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
*Purpose: Liver transplantation (LTx) in pediatrics has become an accepted modality for treatment in end-stage liver disease and irreversible acute liver failure. Left lateral segment…
2019 American Transplant Congress
IgG4 Subclass Class 2 Donor Specific Antibody (DSA) is Associated with Subclinical Rejection in Stable Pediatric Liver Transplant (LT) Recipients with Normal Liver Tests
A. Jackson¹, S. Kanaparthi², B. Burrell³, D. Lucas⁴, R. Vega⁴, A. J. Demetris⁵, S. Feng⁶
¹Surgery, Duke University, Durham, NC, ²The Immune Tolerance Network, Bethesda, MD, ³Immune Tolerance Network, Bethesda, MD, ⁴Medicine, Johns Hopkins University, Baltimore, MD, ⁵Pathology, University of Pittsburgh, Pittsburgh, PA, ⁶Surgery, University of California San Francisco, San Francisco, CA
*Purpose: DSA is a known biomarker of allograft rejection, yet injury phenotype and potential differ across organs. Among pediatric LT recipients entering iWITH (NCT01638559), an…
2019 American Transplant Congress
Use of Marginal Liver Donors in Pediatric Transplantation: Diverse Profiles of Use in Major Transplant Centers
C. S. Hwang¹, A. Aqul², A. Mufti³, S. Hanish¹, D. Desai¹, P. Vagefi¹, M. MacConmara¹
¹Surgery, UT Southwestern, Dallas, TX, ²Pediatrics, UT Southwestern, Dallas, TX, ³Medicine, UT Southwestern, Dallas, TX
*Purpose: Pediatric liver transplantation is highly specialized only a small number of centers have consistent large volume experience. We tested the hypothesis that large volume…
2019 American Transplant Congress
Outcomes after Declining Increased Infectious Risk Kidney Offers for Pediatric Candidates in the United States
M. Bowring, K. Jackson, H. Wasik, A. Neu, J. Garonzik-Wang, C. Durand, N. Desai, A. Massie, D. Segev
Johns Hopkins University, Baltimore, MD
*Purpose: Kidneys from donors at increased infectious risk for disease transmission (IRDs) confer substantial survival benefit in adults, yet the impact of IRDs in pediatric…
2019 American Transplant Congress
Are Protocol Biopsies Necessary for Pediatric Renal Transplant Recipients?
E. Allred, E. Ingulli
Pediatrics, UCSD, San Diego, CA
*Purpose: Renal allograft survival indirectly correlates with acute rejection episodes. Subacute rejection is also associated with decreased graft survival. Protocol biopsies (bxs) have been implemented…
2019 American Transplant Congress
Repeat Liver Transplantation after Failed First Transplant in Childhood: Development of a Retransplant Risk Index
M. Gupta¹, M. Barry², M. Levine³, K. Olthoff³, A. Shaked³, P. Abt³
¹University of Kentucky, Lexington, KY, ²University of California, San Francisco, San Francisco, CA, ³University of Pennsylvania, Philadelphia, PA
*Purpose: Most morbidity and mortality after pediatric liver retransplantation (LRTx) occurs in the first 100 days. We studied factors associated with mortality and graft failure…
2019 American Transplant Congress
Pathologic Vascular Invasion Correlates with Worse Outcome in Hepatoblastoma Patients Treated with Liver Transplantation – A Hepatoblastoma Transplant Consortium Study
T. H. Malik¹, H. Zhu², T. Ha³, S. Commander⁴, C. Trautz⁵, R. Sindhi⁵, S. Kim⁶, K. Vakili⁶, N. Vachharajani⁷, W. Chapman⁷, A. Griesemer⁸, M. Martinez⁸, J. A. Goss⁹, S. Vasudevan¹⁰
¹Baylor College of Medicine, Houston, TX, ²Texas Children's Hospital, Houston, TX, ³Department of Surgery, Baylor College of Medicine, Houston, TX, ⁴Department of Surgery, Duke University School of Medicine, Durham, NC, ⁵Department of Surgery, University of Pittsburgh, Pittsburgh, PA, ⁶Department of Surgery, Boston Children's Hospital, Boston, MA, ⁷Department of Surgery, Washington University School of Medicine in St. Louis, St. Louis, MO, ⁸Department of Surgery, NewYork-Presbyterian Morgan Stanley Children's Hospital, New York, NY, ⁹Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX, ¹⁰Department of Pediatric Surgery, Texas Children's Hospital, Houston, TX
*Purpose: Orthotopic liver transplant (OLTx) is the most common method to treat unresectable hepatoblastoma (HB) in children. There is limited data focusing on the outcomes…
2019 American Transplant Congress
Early Tacrolimus Trough Concentration Variability Could Predict Rejection in Pediatric Liver Transplantation: A Single-Center and Retrospective Research
G. Gu, Q. Xia
Renji Hospital, Shanghai, China
*Purpose: With great development in immunosuppressive therapy, the long-term outcomes and survival time in patients who received solid organ transplantation have been improved remarkably. The…
2019 American Transplant Congress
Disparities in Pediatric Liver Transplant Waitlist Access
S. C. Kim¹, K. Ross¹, E. Hsu², R. Patzer¹, R. J. Lynch¹
¹Emory University, Atlanta, GA, ²University of Washington, Seattle, WA
*Purpose: While disparities in access to liver transplant are well documented among adults, differences in access to the waitlist for children in remote or underserved…
2019 American Transplant Congress
Pediatric Kidneys: One for Two or Two for One?
D. Das, J. Harbell, A. Mathur, A. Singer, W. Hewitt, K. S. Reddy, A. Moss, R. Heilman, C. Jadlowiec
Mayo Clinic AZ, Phoenix, AZ
*Purpose: Kidneys from very young pediatric donors continue to be underutilized due to concerns for technical complications and hyperfiltration injury. The decision to transplant these…