Articles tagged "Pediatric"

2021 American Transplant Congress
Clinically Evident Portal Hypertension (CEPH) is Associated with Low IGF-1 in Children with Chronic Liver Disease
B. Whitehead¹, S. Mohammad¹, S. Kelly¹, J. Josefson², L. Mithal³, E. M. Alonso¹
¹Division of Gastroenterology, Hepatology and Nutrition, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, ²Division of Endocrinology, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, ³Division of Infectious Disease, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
*Purpose: Children with chronic liver disease exhibit growth hormone resistance which is an additional risk factor for sarcopenia and growth failure in this vulnerable population.…
2021 American Transplant Congress
The Pediatric National Liver Review Board: What Happens to Waitlist Registrations with Denied Exception Forms?
J. Foutz¹, C. Martinez¹, A. Henderson¹, E. K. Hsu², E. R. Perito³, J. Heimbach⁴
¹United Network for Organ Sharing, Richmond, VA, ²Seattle Children's Hospital, Seattle, WA, ³UCSF, San Francisco, CA, ⁴Mayo Clinic, Rochester, MN
*Purpose: On 5/14/19, the exceptions review process for pediatric liver transplant (LT) candidates was changed from 11 Regional Review Boards to one National Pediatric Liver…
2021 American Transplant Congress
Pediatric Kidney Transplant Strategy: The Sequence Effect
A. J. Vinson¹, B. Kiberd², P. Acott³, K. Tennankore¹
¹Nova Scotia Health Authority Division of Nephrology, Departm, Halifax, NS, Canada, ²Dalhousie University, Halifax, NS, Canada, ³IWK Health Center, Halifax, NS, Canada
*Purpose: Improvements in patient survival with pediatric end stage kidney disease (ESKD) predicts needing more than one kidney transplant over a child’s lifetime. Timing of…
2021 American Transplant Congress
Kidney Allograft Outcomes in Pediatric Patients Transitioned to Adult Care – A Single Center Study
S. Subramanyam, G. Agarwal, M. Seifert, V. Kumar, G. Towns, K. Wille, S. Ong
University of Alabama at Birmingham, Birmingham, AL
*Purpose: The transition of healthcare for young adults with kidney transplants from pediatric to adult care settings is an area of need, hitherto under-recognized in…
2021 American Transplant Congress
Hepatoportoenterostomy versus Primary Liver Transplantation for Biliary Atresia: A Review of the National Experience
D. Yoeli¹, R. A. Choudhury¹, S. S. Sundaram², C. L. Mack², J. P. Roach³, F. M. Karrer⁴, M. E. Wachs¹, M. A. Adams¹
¹Transplant Surgery, University of Colorado and Children's Hospital Colorado, Aurora, CO, ²Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado and Children's Hospital Colorado, Aurora, CO, ³Pediatric Surgery, University of Colorado, Aurora, CO, ⁴Pediatric Surgery, University of Colorado and Children's Hospital Colorado, Aurora, CO
*Purpose: Kasai hepatoportoenterostomy (HPE) followed by liver transplantation (LT) if needed is the standard of care for children with biliary atresia (BA). Some, however, have…
2021 American Transplant Congress
Degree of T Cell Infiltration Predicts Treatment Response in Pediatric Liver Late Acute Cellular Rejection
M. Rogers, G. Begum, Q. Sun, A. Peters
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
*Purpose: Late acute cellular rejection (ACR) occurs >6mo post-liver transplant and is associated with chronic rejection and allograft loss. Currently, no diagnostic features predict ACR…
2021 American Transplant Congress
The Use of Donor Derived Cell Free DNA in Children to Monitor Therapy of Kidney Rejection
A. Al-Uzri, M. Wright, K. Clark, R. Jenkins
Oregon Health & Science Univ, Portland, OR
*Purpose: Elevated donor-derived cell-free DNA (dd-cfDNA) in the presence of HLA donor-specific antibodies (DSA) are shown to correlate with acute antibody-mediated rejection (AMR) in adult…
2021 American Transplant Congress
En Bloc Kidney Transplantation from Pediatrics Weighing Less Than 5 Kg: Single Center Analysis of 31 Cases
Z. Wang¹, X. Zeng², Q. Xia², J. Peng², H. Xiao², J. Liu², H. Li²
¹Urology, Huazhong University of Science and Technology, Union Hospital, Wuhan, China, ²Urology, Union Hospital, Wuhan, China
*Purpose: Very low bodyweight pediatrics are rarely chosen as donors because of potential higher risk for complications such as early allograft thrombosis, and possible latter…
2021 American Transplant Congress
Impact of Pediatric Living Donor Liver Transplant Center Volume on Waiting List and Post-Transplant Outcomes
D. Yoeli, R. A. Choudhury, H. B. Moore, T. L. Nydam, M. E. Wachs, E. A. Pomfret, M. A. Adams
Transplant Surgery, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, CO
*Purpose: The aim of this study was to compare pediatric liver transplant (pLT) waiting list and post-transplant outcomes by center pediatric living donor liver transplant…
2021 American Transplant Congress
Are All DSA’s the Same? Are We Ready for Precision Medicine in Pediatric LT?
S. E. Shin¹, M. Lee¹, N. Yazigi², K. Khan², S. Kaufman², J. Ahn³, O. Timofeeva⁴, U. Ekong²
¹Georgetown University School of Medicine, Washington, DC, ²Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC, ³Biostatistics, Bioinformatics, & Biomathematics, Georgetown University, Washington, DC, ⁴Histocompatibility Laboratory, Dept. of Pathology & Laboratory Medicine, Georgetown University, Washington, DC
*Purpose: Donor-specific antibodies (DSA) play an uncertain role in rejection after liver transplantation (LT). We hypothesized that evaluation of epitope differences in HLA-DR/DQ mismatching can…