2017 American Transplant Congress
Impact of Pretransplant Panel-Reactive Antibody Level on Ocular Surface Stem Cell Survival and Visual Outcome.
1University of Cincinnati, Cincinnati, OH; 2Cincinnati Eye Institute, Cincinnati, OH
Purpose: Panel-Reactive Antibody (PRA) is a screening test for a range of known human leukocyte antigens which signifies the proportion of the population that the…2016 American Transplant Congress
Impact of Pretransplant Non-Donor-Specific HLA Immunization: Mainly Class 1 Immunization Leads to Poor Immunologic Outcome and Graft Loss.
Nephrology, Charite, Berlin, Germany.
Background Anti-HLA immunization measured as Panel Reactive Antibodies (PRA) is known to have a negative impact on patient and graft survival. The influence of pre-transplant…2016 American Transplant Congress
Highly Sensitized Patients Transplanted via the Eurotransplant Acceptable Mismatch Program Have Excellent Long-Term Graft Survival.
Eurotransplant Reference Laboratory, Leiden University Medical Center, Leiden, Netherlands.
The Eurotransplant Acceptable Mismatch (AM) program has been initiated 25 years ago in order to enhance transplantation of highly sensitized renal transplant candidates. Instead of…2016 American Transplant Congress
Do Highly Sensitized Recipients Benefit from the Immunological Advantages of Zero Mismatched (0MM) Deceased Donors (DD) Kidney Allografts?
HLA 0MM DD transplants have superior outcomes compared with outcomes for grafts with ≥1 HLA mismatches, but when past reports analyzed 0MM outcomes in DD,…2016 American Transplant Congress
Transplanting the Extremely Sensitized Patient: The University of Wisconsin Experience with the New Kidney Allocation System.
Department of Surgery, Division of Transplantation, University of Wisconsin, Madison, WI.
Background: The new UNOS kidney allocation system (KAS) prioritizes the transplant of highly sensitized patients with a calculated Panel Reactive Antibody (cPRA) ≥80 and extremely…2016 American Transplant Congress
Inconsistent HLA Antibody Reactivity Detected with Different Solid-Phase Assays.
Precise determination of HLA antibodies is essential for patients awaiting transplantation. HLA antigens that are recognized by a patient are listed in UNOS as unacceptable…2016 American Transplant Congress
Comparison of EDTA, DTT and Dilutions to Abrogate the Prozone Effect in Luminex-Based HLA Antibody Assays.
Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ.
Mean fluorescence intensity (MFI) values obtained from Luminex-based single antigen bead (SAB) assays is a semi-quantitative result used to determine the relative strength of HLA…2016 American Transplant Congress
Impact of New Kidney Allocation System on Transplant Rates for Highly Sensitized Patients-Center Specific Study.
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Aim: Our renal transplant program promotes transplant of highly sensitized patients (pts) through desensitization and listing only strong antibodies as unacceptable antigens (UAs). UNOS implemented…2016 American Transplant Congress
Kidney Transplant with Low Level DSA and Low Positive B-Flow Crossmatch: An Underappreciated Option for Highly Sensitized Transplant Candidates.
Transplant Center, Mayo Clinic, Rochester, MN.
Introduction: Avoiding DSA is difficult in sensitized patients. A kidney transplant (KTx) with low level DSA with or without a low level B flow cytometric…2016 American Transplant Congress
C1q Donor Specific Antibody Associates with Post Transplant Biopsy Findings in Highly Sensitized Kidney Transplant Recipients.
We performed monitoring of conventional donor specific antibodies (DSA) and C1q binding DSA (C1q DSA) to correlate levels with pathology findings in protocol kidney biopsies…
American Transplant Congress abstracts