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American Transplant Congress abstracts

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Articles tagged "Panel reactive antibodies"

  • 2018 American Transplant Congress

    Can Immunosuppression Maintenance after Renal Allograft Failure Prevent Further Sensitization?

    A. Mena-Gutierrez, K. Alquadan, A. Santos, K. Womer, M. Casey.

    University of Florida, Gainesville.

    After renal graft failure, retransplantation(ReTx) becomes more difficult due to sensitization to alloantigens. In 2013, our center opened a specialty clinic to maintain immunosuppression(IS) after…
  • 2018 American Transplant Congress

    Parsing the 100% CPRA Kidney Transplant Candidates, Who Gets Transplanted?

    D. Keith.

    Medicine, Sacred Heart Hospital, Pensacola, FL.

    Currently the United States kidney allocation system gives priority to candidates with a CPRA of 100% by giving them additional allocation points and providing national…
  • 2018 American Transplant Congress

    Impact of KDPI and CPRA on Outcomes in Kidney Transplant Recipients

    S. Sethi, R. Najjar, A. Peng, A. Vo, S. Jordan, E. Huang.

    Cedars Sinai Medical Center, Los Angeles.

    Introduction: The new KAS has led to a marked increase in kidney transplants among highly sensitized recipients, mostly attributable to higher allocation of low KDPI…
  • 2018 American Transplant Congress

    400 Kidney Paired Donor Transplants at a Single Center; The Methodist San Antonio Experience

    A. Bingaman,1 M. Kapturczak,1 I. Ashlagi,2 C. Murphey.3

    1Methodist Specialty and Transplant Hospital, San Antonio, TX; 2Stanford University, Palo Alto, CA; 3Southwest Immunodiagnostics, San Antonio, TX.

    Background: Kidney paired donation (KPD) has become the standard of care for incompatible living donor pairs. Several mature national KPD programs exist yet KPD transplants…
  • 2018 American Transplant Congress

    Comparison of Bortezomib in Addition to Rituximab Based Treatment of Acute Antibody Mediated Rejection in Kidney Transplantation

    A. Mattiazzi,1,2 J. Pagan,1,2 A. Arunachalam,1 I. De la Cruz Alcantara,1 J. Revollo,2 A. Centeno,2 A. Valdes,1,2 G. Guerra.1,2

    1Nephrology & Hypertension, University of Miami, Miami, FL; 2Miami Transplant Institute, Jackson Memorial Hospital, Miami, FL.

    Purpose:The optimal treatment strategy of acute antibody mediated rejection (AMR) in renal allograft recipients remains undefined. The aim of our study was to compare the…
  • 2018 American Transplant Congress

    Many Highly Sensitized Candidates Still Waiting for Transplant Despite the Kidney Allocation System Change: Making the Case for Incompatible Transplantation

    C. Schinstock, B. Smith, A. Bentall, M. Stegall.

    Von Liebig Center for Transplantation and Clinical Regenerative Medicine, Mayo Clinic, Rochester, MN.

    Introduction: The rate of kidney transplantation in highly sensitized individuals has increased since the kidney allocation system (KAS) change, but it remains unclear who has…
  • 2018 American Transplant Congress

    Generation of Calculated Panel-Reactive Antibody Values Using a Reference Panel of Bone Marrow Donors

    E. Kransdorf,1 L. Gragert,2,4 M. Pando,3 N. Kaur,2 J. Patel,1 I. Kim,1 X. Zhang,1 M. Maiers,4 J. Kobashigawa.1

    1Cedars-Sinai Medical Center, Los Angeles, CA; 2Tulane University School of Medicine, New Orleans, LA; 3Baylor Scott & White, Temple, TX; 4National Marrow Donor Program, Minneapolis, MN.

    Introduction: Calculated panel-reactive antibody (CPRA) is the official metric of sensitization used by the United Network for Organ Sharing (UNOS) for kidney allocation. The reference…
  • 2017 American Transplant Congress

    Unintended Consequence of the New Kidney Allocation System – Disproportionate Allocation of High Quality Kidneys to Highly Sensitized Recipients.

    B. Murthy, N. Galvan, J. Moffett, C. O'Mahony, J. Goss, A. Rana.

    Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX

    Purpose: We hypothesize that improving access to highly sensitized candidates in new KAS would compromise the prime objective of matching the best kidney allografts and…
  • 2017 American Transplant Congress

    C3d-Binding Anti-DQ DSA Is Associated with a High Risk for Late ABMR and Graft Failure in Stable Kidney Transplant Recipients.

    D. Lee,1 B. Kim,2 J. Kim,3 I. Kim,4 M. Chun.5

    1Medicine, Maryknoll Medical Center, Busan, Republic of Korea; 2Laboratyory Medicine, Maryknoll Medical Center, Busan, Republic of Korea; 3Surgery, Maryknoll Medical Center, Busan, Republic of Korea; 4Urology, Maryknoll Medical Center, Busan, Republic of Korea; 5Pathology, Maryknoll Medical Center, Busan, Republic of Korea

    Introduction:Donor specific anti-HLA antibodies (DSA) are a major cause of antibody-mediated rejection (ABMR) and poor graft outcome in kidney transplant recipients (KTR). Critical issue is…
  • 2017 American Transplant Congress

    Impact of Pretransplant Panel-Reactive Antibody Level on Ocular Surface Stem Cell Survival and Visual Outcome.

    A. Govil,1 A. Cheung,2 E. Sarnicola,2 B. Genereux,2 E. Holland.2

    1University of Cincinnati, Cincinnati, OH; 2Cincinnati Eye Institute, Cincinnati, OH

    Purpose: Panel-Reactive Antibody (PRA) is a screening test for a range of known human leukocyte antigens which signifies the proportion of the population that the…
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