Articles tagged "Pancreatitis"

2021 American Transplant Congress
Endocrine Cell Identity and HOMA-B In Patients with Chronic Pancreatitis Undergoing Islet Auto-transplantation
C. A. Beamish¹, O. Gaber², O. M. Sabek²
¹Surgery, Houston Mehodist Hospital, Houston, TX, ²Surgery, Houston Mehodist, Houston, TX
*Purpose: Islet identity loss is an emergent factor in dysglycemia in diabetes, islet transplantation, and chronic pancreatitis (CP). Pancreatectomy and islet auto-transplantation (PIAT) for CP…
2021 American Transplant Congress
TPIAT Outcomes in Diabetic and Non-diabetic Patients
M. A. Kanak, J. B. Spriggs, P. Coughenour, J. Kalivarathan, P. Saravanan, M. Levy
Virginia Commonwealth University, Richmond, VA
*Purpose: Total pancreatectomy with islet auto-transplant (TPIAT) has become a mainstay treatment for patients who suffer from refractory chronic pancreatitis. It has consistently been shown…
2020 American Transplant Congress
Outcomes of Simultaneous Pancreas and Kidney Transplantation Based on Donor Resuscitation
F. Messner¹, J. W. Etra², Y. Yu³, K. Jackson², A. B. Massie², G. Brandacher², S. Schneeberger⁴, C. Margreiter⁴, D. L. Segev²
¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, ³Department of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD, ⁴Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria
*Purpose: It has been hypothesized that transplanting simultaneous pancreas kidney (SPK) grafts from donors with a history of cardiac arrest and cardiopulmonary resuscitation (CACPR) leads…
2020 American Transplant Congress
Evaluation of US Doppler Examination of Portal Flow Dynamics in Patients with Total Pancreatectomy and Autologous Islet Cell Transplant
B. M. Williams, X. Baldwin, J. S. Vonderau, C. S. Desai
University of North Carolina, Chapel Hill, NC
*Purpose: The aim of this study is to evaluate US doppler flow dynamics following total pancreatectomy and autologous islet cell transplant (TPAIT) and establish any…
2020 American Transplant Congress
Can Autologous Islet Cell Transplant Be a Comparable Choice to Parenchymal Preserving Surgery for Patients with Chronic Pancreatitis with Respect to Glycemic Control?
B. M. Williams, X. Baldwin, J. S. Vonderau, M. Hanson, C. S. Desai
University of North Carolina, Chapel Hill, NC
*Purpose: The aim of this study is to examine the difference in glycemic outcomes between total pancreatectomy and autologous islet cell transplant (TPAIT) and parenchymal…
2020 American Transplant Congress
Total Pancreatectomy with Islet Autotransplantation in Diabetic and Prediabetic Patients with Intractable Chronic Pancreatitis
P. J. Bachul¹, D. J. Grybowski¹, R. Anteby², L. Basto¹, L. Perea¹, K. Golab¹, L. Wang¹, M. Tibudan¹, A. Perez-Gutierrez¹, M. Komorniczak³, S. Nagpal⁴, A. Lucander¹, P. Borek¹, M. Dimitrov¹, J. Fung¹, J. B. Matthews¹, P. Witkowski¹
¹Surgery, University of Chicago, Chicago, IL, ²Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ³Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland, ⁴Medicine, University of Chicago, Chicago, IL
*Purpose: Total pancreatectomy with islet autotransplantation (TPIAT) is an effective treatment option for non-diabetic patients with intractable chronic pancreatitis. The outcome and potential benefits for…
2020 American Transplant Congress
TPIAT Outcomes in Diabetic and Non-Diabetic Patients with Chronic Pancreatitis
M. A. Kanak, P. Saravanan, J. Kalivarathan, G. Hobbs, M. F. Levy
Virginia Commonwealth University, Richmond, VA
*Purpose: Total pancreatectomy with islet auto-transplantation (TPIAT) is becoming the standard of care for patients with severe chronic pancreatitis (CP). However, it is necessary to…
2019 American Transplant Congress
Exosomes Carry Stress and Damage Specific miRNAs during Peritransplant Period in TPIAT
P. Saravanan¹, M. Kanak¹, S. Vasu², M. Lawrence², M. Levy¹, B. Naziruddin³
¹Department of Surgery, Virginia Commonwealth University, VCU Health, Richmond, VA, ²Islet Cell Lab, Baylor Scott and White Research Institute, Dallas, TX, ³Simmons Transplant Institute, Baylor Scott and White Medical Center, Dallas, TX
*Purpose: Innate inflammation and hypoxia during peritransplant period significantly affect survival of islet grafts. Markers that can identify stress and/or damage during this early period…
2019 American Transplant Congress
Predicting Metabolic Outcomes in Islet Autotransplantation before Transplantation
M. A. Kanak, P. Saravanan, J. Kalivarathan, Y. Shindo, M. F. Levy
Virginia Commonwealth University, Richmond, VA
*Purpose: Total Pancreatectomy with Islet Auto-transplantation (TPIAT) has been actively performed on patients with severe, debilitating pain of chronic pancreatitis. The outcome of islet transplantation…
2019 American Transplant Congress
Fibrosis Scoring Correlates with Progression of Chronic Pancreatitis, Islet Isolation Yields and Transplant Outcomes in Patients Undergoing Islet Autotransplantation
Y. Liu¹, J. SoRelle², K. Kumano³, S. Vasu³, M. Lawrence⁴, A. Gupta¹, N. Onaca¹, E. Beecherl¹, B. Naziruddin⁴
¹Baylor Simmons Transplant Institute, Dallas, TX, ²UTSouthwestern Medical Center, Dallas, TX, ³Baylor Scott and White Research Institute, Dallas, TX, ⁴Baylor University Medical Ctr, Dallas, TX
*Purpose: Total pancreatectomy with autologous islet transplantation (TPIAT) is a promising procedure for alleviating pain and maintaining glucose homeostasis in chronic pancreatitis (CP) patients. However,…