Articles tagged "Pancreas transplantation"

2021 American Transplant Congress
SPK Transplantation in HIV-positive Recipients
H. Resweber, k. nguyen, H. Curtis, J. Panichella, A. DI Carlo, S. Karhadkar
Temple University School of Medicine, Philadelphia, PA
*Purpose: With the advent of anti-retroviral therapy in the treatment of HIV, mortality in HIV-infected individuals has become less due to complications from viral infection…
2021 American Transplant Congress
Utilization of Donor-Derived Cell-Free DNA Testing in Kidney Transplantation: Do One Month Values Have Any Prognostic Significance?
R. J. Stratta, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, A. Mena-Gutierrez, N. Sakhovskaya, C. Jay
Wake Forest Univ, Winston Salem, NC
*Purpose: Percutaneous renal allograft biopsy is the current gold standard for detecting acute rejection after kidney transplantation (KT). Noninvasive tests such as plasma-based donor-derived cell-free…
2021 American Transplant Congress
Donor Derived Cell-Free DNA (dd-cfDNA) in Pancreas Transplant Recipients
S. Riad¹, H. Sarumi², R. Kandaswamy³
¹Medicine, University of Minnesota, Minneapolis, MN, ²Surgery, University of Minnesota Physicians, Minneapolis, MN, ³Surgery, University of Minnesota, Minneapolis, MN
*Purpose: Data on the role of DD-cfDNA after pancreas transplantation is lacking. Herein we report on our center experience with DD-cfDNA in 10 unique SPK…
2021 American Transplant Congress
Simultaneous Pancreas-Kidney Transplantation in Caucasian versus African American Patients: Does Recipient Ethnicity Influence Outcomes?
J. Rogers¹, A. Farney², G. Orlando², C. Jay², K. Gurung², B. Sharda², A. Reeves-Daniel³, A. Mena-Gutierrez³, N. Sakhovskaya³, W. Doares⁴, S. Kaczmorski⁴, M. Magid⁴, M. Gautreaux², R. Stratta²
¹Wake Forest Baptist Medical Center, Winston-Salem, NC, ²Department of Surgery, Wake Forest Baptist Medical Center, Winston-Salem, NC, ³Internal Medicine, Wake Forest Baptist Medical Center, Winston-Salem, NC, ⁴Department of Pharmacy, Wake Forest Baptist Medical Center, Winston-Salem, NC
*Purpose: The influence of African American (AA) recipient ethnicity on outcomes following simultaneous pancreas-kidney transplantation (SPKT) in the modern era is uncertain.*Methods: From 11/01 to…
2021 American Transplant Congress
Distal Allograft Pancreatectomy for Graft Salvage After Pancreas Transplantation
D. Soma, T. Nikumbh, A. J. Lutz, J. A. Powelson, J. A. Fridell
Transplant Division, Department of Surgery, Indiana University School of Medicine, Indianapolis, IN
*Purpose: Early pancreas allograft failure most commonly results from vascular thrombosis. Immediate surgical intervention may permit pancreas allograft salvage, typically requiring thrombectomy. In cases of…
2021 American Transplant Congress
Epidemiology and Risk Factors for Invasive Fungal Infection in Pancreas Transplant in the Absence of Fungal Prophylaxis
J. Burkey¹, J. M. Chen², A. A. Sharfuddin², M. S. Yaqub², A. J. Lutz², J. A. Powelson², J. A. Fridell², N. Barros²
¹Butler University College of Pharmacy and Health Sciences, Indianapolis, IN, ²Indiana University Health, Indianapolis, IN
*Purpose: Invasive fungal infections (IFI) remain a rare yet dreaded complication following pancreas transplantation. Current guidelines recommend antifungal prophylaxis in patients with 1 or more…
2021 American Transplant Congress
Baseline Levels of Dd-cf Dna After Pancreas Transplantation: Using Dd-cfdna as an Indicator for Pancreas Rejection and Biopsy Avoidance
A. Yoo, I. Qian, A. Riedel, C. Cazac, A. Bartosic, J. S. Bromberg, J. Scalea
Department of Surgery, Division of Transplant, University of Maryland School of Medicine, Baltimore, MD
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) testing, which has been previously validated for monitoring kidney transplant (KTx) rejection, may provide an alternative to pancreas biopsy that…
2021 American Transplant Congress
Islet Isograft Transplantation Improves Insulin Sensitivity in a Murine Model of Type 2 Diabetes
S. Lim, M. Choi, M. Kim, Y. Wee, H. Kwon, C. Jung, Y. Kim, D. Han, S. Shin
Asan Medical Center, Seoul, Songpa, Korea, Republic of
*Purpose: Type 2 diabetes develops in the presence of chronic overnutrition and genetic susceptibility, and causes insulin resistance and relative insulin deficiency. We hypothesized that…
2021 American Transplant Congress
Donor Derived Cell Free DNA Identifies Rejection in Simultaneous Pancreas Kidney Transplant Recipients
M. Williams¹, S. Ghosh², L. L. Jenkins², M. Hertl¹, S. Saltzberg³, V. Peev³, E. Chan¹, E. Hollinger¹, E. Schadde¹, O. Olaitan¹
¹Department of Surgery, Rush University Medical Center, Chicago, IL, ²CareDx, Inc., Brisbane, CA, ³Department of Internal Medicine, Rush University Medical Center, Chicago, IL
*Purpose: Increased level of donor-derived cell-free DNA (dd-cfDNA) has proven to be a sensitive marker for allograft rejection after solid organ transplant, particularly heart and…
2021 American Transplant Congress
Bone Marrow-Derived Mesenchymal Stem Cells Improve Rat Islet Graft Revascularization by Upregulating Isl1
W. Ying, J. Wang, X. Ding
Kidney Transplantation, The First Affiliated Hospital of Xi'an Jiaotong University, Xi An, China
*Purpose: Revascularization of the transplant islet is a crucial step that defines the success rate of patient recovery. Though bone marrow-derived mesenchymal stem cells (BMSCs)…

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