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American Transplant Congress abstracts

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Articles tagged "Pancreas transplantation"

  • 2022 American Transplant Congress

    Depletion of Donor Macrophages Permits Post-Transplant Tolerance Induction

    M. Dilts1, A. Dangi2, X. Luo3

    1Pathology, Duke University, Durham, NC, 2Medicine, Duke University, Durham, NC, 3Duke University School of Medicine, Durham, NC

    *Purpose: Using donor splenocytes fixed with cross-linker ethylcarbodiimide (ECDI-SPs), our lab has induced tolerance in a variety of murine and non-human primate models when one…
  • 2022 American Transplant Congress

    Comparing Infection Rate Between Steroid Withdrawal and Ongoing Maintenance Among Simultaneous Pancreas-Kidney Transplant Recipients

    M. McCord1, Z. Yetmar2, A. Lemke1, K. Mara3, M. T. Seville4, W. Bosch5, P. Dean6, E. Beam2, S. Bernard1

    1Department of Pharmacy, Mayo Clinic, Rochester, MN, 2Division of Infectious Diseases, Mayo Clinic, Rochester, MN, 3Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 4Division of Infectious Diseases, Mayo Clinic Arizona, Scottsdale, AZ, 5Division of Infectious Diseases, Mayo Clinic, Jacksonville, FL, 6Division of Transplantation Surgery, Mayo Clinic, Rochester, MN

    *Purpose: Compare infection rates of simultaneous pancreas-kidney transplant (SPK) recipients who continue maintenance steroids to those with steroid withdrawal post transplant.*Methods: This study is a…
  • 2022 American Transplant Congress

    DCD vs DBD Pancreas Transplant Outcome – A Comprehensive Registry Analysis

    A. C. Gruessner1, S. J. Saggi2, R. Gruessner1

    1SUNY Downstate Medical Center, Brooklyn, NY, 2Medicine, SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: Pancreas transplantation offers long-term independence from insulin injections for patients with labile diabetes mellitus. After a decade of decline (2004-2015), the number of pancreas…
  • 2022 American Transplant Congress

    Longitudinal Monitoring of Simultaneous Pancreas and Kidney Transplant and Pancreas After Kidney Recipients Using Donor-Derived Cell-Free DNA

    N. M. Ali1, J. Miles2, Z. Stewart3

    1Transplant Institute, NYU Langone Health, New York, NY, 2CareDx, Brisbane, NY, 3Transplant Institute, NYU Langone Health, New York, NM

    *Purpose: The utility of dd-cfDNA in patients undergoing pancreas transplantation has not been well studied. Pancreatic rejection remains a major clinical concern. Early identification of…
  • 2022 American Transplant Congress

    Using a Unique Repository of Pancreas Transplant Biopsies to Validate the Tissue Common Response Module (tCRM) Score as a Tool to Assess the Severity of Pancreas Transplant Rejection

    Y. Kelly1, A. Zarinsefat1, R. Meier2, M. Sarwal1, P. Stock1, Z. Laszik1, T. Sigdel1

    1University of California, San Francisco, San Francisco, CA, 2University of Maryland Medical Center, Baltimore, MD

    *Purpose: Analysis of transcriptional data from kidney, heart, liver, and lung transplant rejection led to development of the tissue Common Response Module (tCRM) score based…
  • 2022 American Transplant Congress

    Ultra-Short Duration Prophylaxis for Hepatitis C Donor Positive to Recipient Negative Simultaneous Kidney/Pancreas Transplants

    G. Gupta, I. Yakubu, A. Khan, R. Sterling

    Virginia Commonwealth University, Richmond, VA

    *Purpose: Recent trials have successfully utilized a strategy of hepatitis C virus (HCV) D+ [Donor nucleic acid test (NAT) positive]/R- (Recipient NAT negative) kidney and/or…
  • 2022 American Transplant Congress

    Immune Cell Phenotype of Acute Rejection of Pancreas Allografts by RNA Sequencing Analysis

    C. Hughes, H. Yang, C. Snopkowski, C. Li, D. M. Dadhania, S. Sultan, C. Hartono, M. Suthanthiran, S. V. Seshan, T. Muthukumar

    Weill Cornell Medicine, New York, NY

    *Purpose: Long term survival of pancreas allografts are inferior to kidney allografts. Molecular mechanisms underpinning pancreas allograft rejection and failure have not been explored in…
  • 2022 American Transplant Congress

    Metabolic Outcomes After Simultaneous Pancreas Kidney Transplant from Donation After Circulatory Death Donors – The UK Registry Analysis

    J. Gopal, A. McLean, A. Muthusamy

    Imperial College Renal and Transplant Center, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom

    *Purpose: DCD pancreas transplantation is established as a valuable cohort to expand the pancreas donor pool, with equivalent graft & patient survival compared to pancreases…
  • 2021 American Transplant Congress

    Epidemiology and Risk Factors for Invasive Fungal Infection in Pancreas Transplant in the Absence of Fungal Prophylaxis

    J. Burkey1, J. M. Chen2, A. A. Sharfuddin2, M. S. Yaqub2, A. J. Lutz2, J. A. Powelson2, J. A. Fridell2, N. Barros2

    1Butler University College of Pharmacy and Health Sciences, Indianapolis, IN, 2Indiana University Health, Indianapolis, IN

    *Purpose: Invasive fungal infections (IFI) remain a rare yet dreaded complication following pancreas transplantation. Current guidelines recommend antifungal prophylaxis in patients with 1 or more…
  • 2021 American Transplant Congress

    Baseline Levels of Dd-cf Dna After Pancreas Transplantation: Using Dd-cfdna as an Indicator for Pancreas Rejection and Biopsy Avoidance

    A. Yoo, I. Qian, A. Riedel, C. Cazac, A. Bartosic, J. S. Bromberg, J. Scalea

    Department of Surgery, Division of Transplant, University of Maryland School of Medicine, Baltimore, MD

    *Purpose: Donor-derived cell-free DNA (dd-cfDNA) testing, which has been previously validated for monitoring kidney transplant (KTx) rejection, may provide an alternative to pancreas biopsy that…
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