ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Pancreas transplantation"

  • 2015 American Transplant Congress

    Post-Donation Outcomes in 46 Live Pancreas Donors

    V. Kirchner, D. Sutherland, T. Dunn, E. Finger, T. Pruett, R. Kandaswamy.

    Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, MN.

    Background: Live donor segmental pancreas transplants have been performed selectively to increase the pool of donors, minimize cold ischemia time, and to avoid brain death.…
  • 2015 American Transplant Congress

    Long Term Follow Up Reveals Satisfactory Renal Outcome in Pacreas After Kidney Transplantation (PAK)

    R. Banga, V. Dadlani, W. Kremers, E. Lorenz, P. Dean, M. Stegall, Y. Kudva.

    Mayo Clinic, Rochester.

    Objective: PAK offers diabetic ESRD patients' opportunity to avoid or minimize dialysis using living kidney donation, followed by cadaveric pancreas transplantation thereafter to restore euglycemia,…
  • 2015 American Transplant Congress

    Inadequate Overall Immunosuppression Is a Risk for Late Acute Rejection Despite Alemtuzumab Induction in Simultaneous Pancreas Kidney Transplant Recipients

    J. Bank,1 M. Mallat,1 P. van der Boog,1 D. Braat,2 J. Ringers,2 M. Vergunst,3 S. Heidt,3 F. Claas,3 M. Reinders,1 J. de Fijter.1

    1Nephrology, LUMC, Leiden, Netherlands; 2Surgery, LUMC, Leiden, Netherlands; 3IHB, LUMC, Leiden, Netherlands.

    Introduction: Simultaneous pancreas-kidney transplantation (SPK) has become the treatment of choice for patients with end-stage renal disease due to Type 1 Diabetes Mellitus. SPK is…
  • 2015 American Transplant Congress

    10 Year Experience Using a Steroid Free Three Drug Maintenance Immunosuppression Regimen for Pancreas Transplant Alone: Comparison of Induction With Rabbit Antithymocyte Globulin +/- Rituximab

    J. Fridell,1 R. Mangus,1 J. Chen,2 M. Mujtaba,3 T. Taber,3 M. Goble,1 J. Powelson.1

    1Surgery, Indiana University School of Medicine, Indianapolis, IN; 2Pharmacy, Indiana University School of Medicine, Indianapolis, IN; 3Medicine, Indiana University School of Medicine, Indianapolis, IN.

    Graft survival following pancreas transplant alone (PTA) is inferior to other pancreas transplants. Steroid elimination is appealing, but a two drug maintenance strategy may be…
  • 2015 American Transplant Congress

    Effect of Donor Age On Pancreas Transplantation Outcome

    A. Rathnasamy Muthusamy,1 G. Vrakas,1 S. Mittal,1 S. Reddy,1 I. Quiroga,1 J. Gilbert,1 R. Ploeg,2 E. Sharples,1 S. Sinha,1 A. Vaidya,1 P. Friend.2

    1Transplant Surgery, Churchill Hospital, Oxford, United Kingdom; 2Nuffield Department of Surgery, University of Oxford, Oxford, United Kingdom.

    The global increase in the average donor age over the last decade has resulted in widespread acceptance of pancreases from older donors for transplantation. This…
  • 2015 American Transplant Congress

    Donor Specific Antibodies (DSA) Increase the Risk for Rejection After Pancreas Transplantation Qithout Negatively Impacting Survival

    M. Marquez, M. Dib, G. Sapisochin, J. Laurence, A. Barbas, F. Bazerbachi, A. Norgate, M. Selzner, P. Greig, I. McGilvray, M. Cattal.

    Multi-Organ Transplant, University Health Network, Toronto, ON, Canada.

    Donor-specific antibodies (DSA) have been associated with increased rejection and lower kidney transplant survival. The impact of DSA on pancreas transplant outcomes in patients with…
  • 2015 American Transplant Congress

    Excessive Weight Gain After Pancreas Transplant: Transitioning from Type 1 to Type 2 Diabetes?

    A. Islam,1 A. Lawless,1 L. Teeter,3 E. Graviss,3 D. Victor,4 A. Sadhu,4 S. Patel,6 A. Gaber,1 R. Knight.1

    1Department of Surgery, Houston Methodist Hospital, Houston, TX; 2Department of Pathology & Genomic Medicine, Houston Methodist Hospital, Houston, TX; 3Department of Medicine, Houston Methodist Hospital, Houston, TX; 4Department of Pharmacy, Houston Methodist Hospital, Houston, TX.

    AIM:Excessive weight gain (EWG) after pancreas transplantation may increase the risk of post-transplant diabetes mellitus and metabolic syndrome. This study aimed to define the incidence,…
  • 2015 American Transplant Congress

    Differences in Genetic Variants That Influence Long-Term Graft Function Between Pancreas Transplant Donors and Recipients

    M. Simmonds,1 C. Duff,1 A. Hamilton,1 S. Mittal,2,3,4 M. Barnardo,2,3 S. Fuggle,2,3 P. Friend,2,3 S. Gough.1,4

    1Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), University of Oxford, Oxford, United Kingdom; 2Oxford Transplant Centre, Oxford University Hospitals NHS Trust, Oxford, United Kingdom; 3Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom; 4Oxford National Institute for Health Research Biomedical Research Centre, Oxford, United Kingdom.

    Genetic variation in caveolin-1, involved in signal transduction and tissue fibrosis, within pancreas transplant donors has been previously shown to correlate with decreased long-term graft…
  • 2015 American Transplant Congress

    Import Pancreas Transplants: Good from Far or Far from Good?

    J. Rogers, A. Farney, G. Orlando, A. Reeves-Daniel, A. Palanisamy, H. El-Hennawy, M. Khan, M. Gautreaux, S. Iskandar, R. Stratta.

    General Surgery-Transplantation, Wake Forest Baptist Medical Center, Winston-Salem, NC.

    Background: Many transplant (tx) programs are reluctant to import pancreas allografts because of concerns that outcomes might be inferior to locally procured organs. Methods: Single…
  • 2015 American Transplant Congress

    Impact of HMOX1 Genetic Variation in Pancreas Transplant Recipients On Long-Term Graft Outcome

    C. Duff,1 A. Hamilton,1 S. Mittal,2,3,4 M. Barnardo,2,3 S. Fuggle,2,3 P. Friend,2,3 S. Gough,1,4 M. Simmonds.1

    1Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), University of Oxford, Oxford, United Kingdom; 2Oxford Transplant Centre, Oxford University Hospitals NHS Trust, Oxford, United Kingdom; 3Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom; 4Oxford National Institute for Health Research Biomedical Research Centre, Oxford, United Kingdom.

    Variation within the heme oxygenase 1 (HMOX1) gene, essential for heme catabolism and a known inflammatory and immune regulator, is proposed to play a role…
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