Articles tagged "Pancreas transplantation"

2015 American Transplant Congress
A Preliminary Study of Using Small Intestinal Submucosa Scaffolds Coated Islets and Mesenchymal Stem Cells to Built Artificial Pancreas
D. Wang, X. Ding, W. Xue, J. Zheng, X. Feng, X. Tian, Y. Li.
Department of Renal Transplant, Center of Nephropathy, The First Affiliated Hospital, Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Background: Although islet transplantation successful applied, shortage of donors, poor islet survival and toxicity of immunosuppressants often reduce the graft functional lifetime. Tissue engineered scaffold…
2015 American Transplant Congress
Allograft Pancreatectomy: Indications and Outcomes
S. Nagai, J. Powelson, R. Mangus, J. Fridell.
Transplant Surgery, Indiana University School of Medicine, Indianapolis, IN.
Background: Indications for allograft pancreatectomy have not been clearly established, but cause and timing of graft loss, clinical symptoms and candidacy for pancreas retransplantation are…
2015 American Transplant Congress
Hypothermic Machine Perfusion Improves the Quality of Marginal Donor Pancreata
M. Leemkuil,¹ M. Engelse,² R. Ploeg,³ E. de Koning,² C. Krikke,¹ H. Leuvenink.¹
¹Surgery, University Medical Center Groningen, Groningen, Netherlands; ²Nephrology, Leiden University Medical Center, Leiden, Netherlands; ³Transplant Biology, Oxford Transplant Center, Oxford, United Kingdom.
Introduction. Pancreas or islet transplantation is considered the most effective treatment for patients with type 1 diabetes mellitus. Due to the persistent organ shortage, pancreata…
2015 American Transplant Congress
Simultaneous Cadaveric Pancreas, Living-Donor Kidney Transplantation: Single Center Experience
Y. Kim, J. Jung, H. Cho, J. Hong, J. Choi, B. Choi, S. Shin, D. Han.
Surgery and Organ Transplant Center, Asan Medical Center, Seoul, Korea.
BackgroundSimultaneous cadaveric pancreas and living-donor kidney transplantation(SPLK) is an attractive approach for uremic Type I diabetic patients, due to its distinct advantages from living kidney…
2015 American Transplant Congress
Bladder Drainage of Pancreas Transplants Alone: Friend or Foe?
M. Bellini,¹ G. Spoletini,² S. Reddy,¹ J. Gilbert,¹ I. Quiroga,¹ R. Ploeg,¹ E. Sharples,³ S. Sinha,¹ A. Vaidya,¹ P. Friend.¹
¹Nuffield Department of Surgery, Oxford University Hospital NHS Trust, Oxford, United Kingdom; ²Department of Hepatobiliary and Transplant Surgery, Royal Free London NHS Trust, London, United Kingdom; ³Nuffield Department of Medicine, Oxford University Hospital NHS Trust, Oxford, United Kingdom.
Introduction: Immunological monitoring of Pancreas Transplants Alone (PTA) remains a challenge and bladder drainage is thought to facilitate early detection of rejection but may lead…
2015 American Transplant Congress
Early Hospital Readmission After Simultaneous Pancreas-Kidney Transplantation
E. King,¹ L. Kucirka,¹ M. McAdams-DeMarco,^1,2 A. Massie,^1,2 D. Segev.^1,2
¹Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD; ²Epidemiology, Johns Hopkins University, School of Public Health, Baltimore, MD.
Background: Early hospital readmission (EHR) is associated with increased morbidity and mortality after kidney transplantation. However, following simultaneous pancreas-kidney transplantation (SPK), EHR rates are unknown,…
2015 American Transplant Congress
Pancreas Transplant Sera Improves the Function and Proliferation of Endothelial Cells
J. Pollett, L. Margetich, N. Thai.
Transplant Services, Allegheny General Hospital, Pittsburgh, PA.
Pancreas transplantation (Tx) allows for the study of diabetes by examining the reversal of the disease. Previously, we observed that after pancreas Tx many patients'…
2015 American Transplant Congress
Impact of Donor Hemoglobin A1c On Pancreas Graft Survival
K. Collins,¹ J. Garonzik-Wang,¹ E. King,² M. Doyle,¹ J. Lowell,¹ S. Shenoy,¹ Y. Lin,¹ J. Wellen,¹ W. Chapman,¹ D. Segev.²
¹Abdominal Transplant, Washington University, Saint Louis, MO; ²Surgery, Johns Hopkins University, Baltimore, MD.
A goal in selection of ideal donor pancreata is to avoid grafts with a predisposition to type-two diabetes. The HgA1c assay is a validated estimate…
2015 American Transplant Congress
Why Are Pancreas Transplant Volumes Declining?
R. Carrico,¹ J. Fridell,² J. Odorico,³ H. Yeh,⁴ K. Tyler,¹ S. Niederhaus.⁵
¹UNOS, Richmond, VA; ²Indiana Univ School of Medicine, Indianapolis, IN; ³Univ Wisconsin Hospital and Clinics, Madison, WI; ⁴Massachusetts General Hospital, Boston, MA; ⁵Univ of Maryland Medical System, Baltimore, MD.
Background: Pancreas transplant volumes have been decreasing in the US since the mid-2000s. It has been conjectured that poor utilization of deceased donor pancreata (as…
2015 American Transplant Congress
Reconsideration of Age Limits for Pancreas Transplantation
J. Scalea, H. Sollinger, R. Redfield, M. Rizzari, D. Kaufman, J. Odorico.
Div. of Transplantation, Dept. of Surgery, University of Wisconsin, Madison, WI.
Introduction: Pancreas transplantation (PTx) remains the only strategy for reinstitution of long-term insulin production and outcomes have progressively improved. Yet, historically, centers have employed age-limits…