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American Transplant Congress abstracts

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Articles tagged "Pancreas transplantation"

  • 2022 American Transplant Congress

    Solid Organ Pancreas Transplantation Offers Superior Glycemic Control Compared to State of the Art Insulin Delivery with Continuous Glucose Monitoring (CGM)

    K. R. McCune, G. K. Dube, P. R. Sandoval, L. E. Ratner

    Columbia University, New York, NY

    *Purpose: Advanced insulin delivery systems with CGM fail to keep serum glucose within range (70-180 mmol/L) 30-40% of the time resulting in Hgb A1C goals…
  • 2022 American Transplant Congress

    Donor-Derived Duodenal Adenocarcinoma of a Bladder-Drained Pancreas Allograft

    D. Isaacson1, J. Steggerda1, Y. Xue1, G. B. Auffenberg2, N. N. Katariya3

    1Northwestern University, Chicago, IL, 2Urology of St. Louis, St. Louis, MO, 3Mayo Clinic, Phoenix, AZ

    *Purpose: Donor-derived malignancies are rare but frequently present with aggressive pathology and high mortality rates [PMID 32627325]. The urologic literature demonstrates an increased risk of…
  • 2022 American Transplant Congress

    Metabolic Outcomes After Pancreas Transplant Alone from Donation After Circulatory Death Donor – The UK Registry Analysis

    J. Gopal, A. McLean, A. Muthusamy

    Imperial College Renal and Transplant Center, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom

    *Purpose: Extrapolating data from early DCD (donation after circulatory death) kidney transplantation, pancreas transplants from DCD grafts were feared to have worse metabolic outcomes. Hence,…
  • 2022 American Transplant Congress

    Comparison of Perioperative Antibiotic Prophylaxis Regimens on Surgical Site Infections in Pancreas Transplant Recipients

    Z. A. Yetmar1, M. McCord2, B. Lahr3, A. Lemke2, P. G. Dean4, Y. C. Kudva5, M. T. Seville6, W. Bosch7, S. A. Bernard2, E. Beam1

    1Division of Infectious Diseases, Mayo Clinic, Rochester, MN, 2Department of Pharmacy, Mayo Clinic, Rochester, MN, 3Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 4Division of Transplantation Surgery, Mayo Clinic, Rochester, MN, 5Division of Endocrinology, Diabetes, Metabolism & Nutrition, Mayo Clinic, Rochester, MN, 6Division of Infectious Diseases, Mayo Clinic, Scottsdale, AZ, 7Division of Infectious Diseases, Mayo Clinic, Jacksonville, FL

    *Purpose: Pancreas transplant recipients are at high risk of surgical site infection (SSI), with rates ranging from 9-45%. Several risk factors for SSI have been…
  • 2022 American Transplant Congress

    Hepatitis C (HCV) Positive Recipients and/or Donors in Pancreas Transplantation – A Registry Analysis

    A. C. Gruessner, R. Gruessner

    SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: Pancreas transplantation (PT) is the best long-term option for patients with labile diabetes and end-stage-renal disease. The mortality on the waitlist is high; patients…
  • 2022 American Transplant Congress

    Depletion of Donor Macrophages Permits Post-Transplant Tolerance Induction

    M. Dilts1, A. Dangi2, X. Luo3

    1Pathology, Duke University, Durham, NC, 2Medicine, Duke University, Durham, NC, 3Duke University School of Medicine, Durham, NC

    *Purpose: Using donor splenocytes fixed with cross-linker ethylcarbodiimide (ECDI-SPs), our lab has induced tolerance in a variety of murine and non-human primate models when one…
  • 2022 American Transplant Congress

    Comparing Infection Rate Between Steroid Withdrawal and Ongoing Maintenance Among Simultaneous Pancreas-Kidney Transplant Recipients

    M. McCord1, Z. Yetmar2, A. Lemke1, K. Mara3, M. T. Seville4, W. Bosch5, P. Dean6, E. Beam2, S. Bernard1

    1Department of Pharmacy, Mayo Clinic, Rochester, MN, 2Division of Infectious Diseases, Mayo Clinic, Rochester, MN, 3Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 4Division of Infectious Diseases, Mayo Clinic Arizona, Scottsdale, AZ, 5Division of Infectious Diseases, Mayo Clinic, Jacksonville, FL, 6Division of Transplantation Surgery, Mayo Clinic, Rochester, MN

    *Purpose: Compare infection rates of simultaneous pancreas-kidney transplant (SPK) recipients who continue maintenance steroids to those with steroid withdrawal post transplant.*Methods: This study is a…
  • 2022 American Transplant Congress

    DCD vs DBD Pancreas Transplant Outcome – A Comprehensive Registry Analysis

    A. C. Gruessner1, S. J. Saggi2, R. Gruessner1

    1SUNY Downstate Medical Center, Brooklyn, NY, 2Medicine, SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: Pancreas transplantation offers long-term independence from insulin injections for patients with labile diabetes mellitus. After a decade of decline (2004-2015), the number of pancreas…
  • 2022 American Transplant Congress

    Longitudinal Monitoring of Simultaneous Pancreas and Kidney Transplant and Pancreas After Kidney Recipients Using Donor-Derived Cell-Free DNA

    N. M. Ali1, J. Miles2, Z. Stewart3

    1Transplant Institute, NYU Langone Health, New York, NY, 2CareDx, Brisbane, NY, 3Transplant Institute, NYU Langone Health, New York, NM

    *Purpose: The utility of dd-cfDNA in patients undergoing pancreas transplantation has not been well studied. Pancreatic rejection remains a major clinical concern. Early identification of…
  • 2022 American Transplant Congress

    Using a Unique Repository of Pancreas Transplant Biopsies to Validate the Tissue Common Response Module (tCRM) Score as a Tool to Assess the Severity of Pancreas Transplant Rejection

    Y. Kelly1, A. Zarinsefat1, R. Meier2, M. Sarwal1, P. Stock1, Z. Laszik1, T. Sigdel1

    1University of California, San Francisco, San Francisco, CA, 2University of Maryland Medical Center, Baltimore, MD

    *Purpose: Analysis of transcriptional data from kidney, heart, liver, and lung transplant rejection led to development of the tissue Common Response Module (tCRM) score based…
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