Articles tagged "Outcome"

2022 American Transplant Congress
Secular Trends in Development of ESRD Following Liver Transplant
J. M. Ruck¹, L. Zeiser¹, A. Massie², D. Segev³, E. King¹
¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Johns Hopkins School of Medicine, Baltimore, MD, ³Johns Hopkins University, Baltimore, MD
*Purpose: End-stage renal disease (ESRD) post-liver transplant (LT) is associated with increased mortality, but ESRD incidence and risk factors in LT recipients (LTRs) remain poorly…
2022 American Transplant Congress
Patient Definitions of Transplant Success of Upper Extremity VCA
M. Downey¹, B. Kuramitsu², J. Gacki-Smith², K. Vanterpool¹, M. Luken³, M. Nordstrom³, T. Riggleman³, C. Cooney¹, M. Levan¹, S. Tintle³, G. Brandacher¹, S. Jensen², G. Dumanian², E. Gordon²
¹Johns Hopkins University, Baltimore, MD, ²Northwestern University, Chicago, IL, ³Walter Reed National Military Medical Center, Bethesda, MD
*Purpose: Little is known about how to measure "success" of upper extremity (UE) vascularized composite allotransplantation (VCA) given its relative novelty and low frequency. While…
2022 American Transplant Congress
Placement of COVID Positive Organs: An Early Analysis
A. M. Hawxby, R. Ketcham, J. P. Orlowski, R. Squires, C. Hostetler
Organ Recovery, LifeShare Transplant Donor Services of Oklahoma, Oklahoma City, OK
*Purpose: Until recently, donor COVID positivity was seen as a contraindication for donation or transplantation. Our OPO has recently adopted a practice in which organs…
2022 American Transplant Congress
A Comparison of Self-Reported Physical Function to In-Person Frailty Assessments for the Prediction of Rehospitalizations After Kidney Transplantation
E. Lorenz¹, C. Kennedy¹, C. Schinstock¹, A. Kukla¹, D. Eton¹, H. Wadei², G. Mour³, P. Dean⁴, A. Rule¹, N. LeBrasseur¹, A. Cheville¹
¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Jacksonville, FL, ³Mayo Clinic, Scottsdale, AZ, ⁴Mayo Clinic Rochester, Rochester, MN
*Purpose: Rehospitalizations are common after kidney transplantation (KT) and associated with increased cost, allograft failure, and death. Physical frailty as defined by Fried criteria has…
2022 American Transplant Congress
Characteristics and Outcomes of Patients Admitted for Acute Alcoholic Hepatitis Before and During the COVID-19 Pandemic
M. S. Anderson¹, S. Uttal², M. Bertha³, K. Jencks², H. Asefah², A. Gustafson³, K. N. Truitt³, P. Maddur³, J. Mellinger²
¹Surgery, Michigan Medicine, Ann Arbor, MI, ²Internal Medicine, Michigan Medicine, Ann Arbor, MI, ³Internal Medicine, Northwestern Memorial Hospital, Chicago, IL
*Purpose: Despite known increases in alcohol use, changes in alcohol-associated liver disease rates during COVID-19 have not been well characterized. We compared the incidence and…
2022 American Transplant Congress
Resistance Isn’t Futile: The Independent Effect of Pumping Resistance on Long-Term Kidney Graft Survival
D. Stewart¹, J. Foutz¹, L. Kamal², G. Gupta²
¹United Network for Organ Sharing, Richmond, VA, ²Virginia Commonwealth University Health, Richmond, VA
*Purpose: Kidneys are pumped for therapeutic (to mitigate deleterious effects of ischemia), practical (to facilitate transplant scheduling), and prognostic (to assess organ quality) purposes. Yet…
2022 American Transplant Congress
A Multi-Center Study Assessing the Association of Frailty with Infection in Kidney Transplant Recipients
M. Malinis¹, M. Abidi², E. Benamu², N. Jakharia³, N. Law⁴, R. Sigler⁴, R. Nog⁵, S. Olivier⁵, S. Taimur⁶, N. Theodoropoulos⁷, J. Schaenman⁸
¹Yale University School of Medicine, New Haven, CT, ²University of CO, Aurora, CO, ³Stanford, Palo Alto, CA, ⁴UCSD, San Diego, CA, ⁵Westchester Med Ctr, Westchester, NY, ⁶Mount Sinai SOM, New York, NY, ⁷Univ of MA, Worcester, MA, ⁸UCLA, Los Angeles, CA
*Purpose: Frailty is a multi-dimensional characterization of decreased reserve and diminished response to stressors in older adults. Frailty at the time of transplant has been…
2022 American Transplant Congress
Low Fixed Tacrolimus Starting Dose and the Correlation with Renal Allograft Rejection
R. Davoudi, E. Kitchel, S. Lee, T. Tan, T. Sievers, S. Bunnapradist
David Geffen School of Medicine, Los Angeles, CA
*Purpose: Achieving a tacrolimus therapeutic trough concentration (C0) by post-operative day (POD) 3-7 has been associated with a reduced risk for rejection. Although FDA prescribing…
2022 American Transplant Congress
The Role of Gastrointestinal Pathogen PCR Testing in Liver Transplant Recipients Hospitalized with Diarrheal Illness
C. K. Ching¹, Y. R. Nobel², M. R. Pereira³, E. C. Verna⁴
¹Department of Medicine, Columbia University Medical Center, New York, NY, ²Division of Digestive and Liver Diseases, Columbia University Medical Center, New York, NY, ³Division of Infectious Diseases, Columbia University Medical Center, New York, NY, ⁴Center for Liver Disease and Transplantation, Columbia University Medical Center, New York, NY
*Purpose: Diarrhea is a common complication among liver transplant (LT) recipients and can result in significant morbidity. The development of PCR-based multiplex gastrointestinal (GI) pathogen…
2022 American Transplant Congress
Detection of Early Graft Injury After Liver Transplantation with Blood-Bile Ratio of Tacrolimus: The TUBE Trial
M. M. Pascale¹, G. Bianco¹, L. Ferri¹, F. Giovinazzo¹, A. Liguori², G. Marrone², A. Grieco², S. Agnes¹
¹General Surgery and Liver Transplant Unit, Fondazione IRCSS - Policlinico "A. Gemelli", Roma, Italy, ²Transplant Hepatology Unit, Fondazione IRCSS - Policlinico "A. Gemelli", Roma, Italy
*Purpose: The aim of the“Tacrolimus in Bile”(TUBE)Trial is the creation of a laboratory parameter for the early detection of hepatic injury after liver transplant.*Methods: TUBE…