Articles tagged "Outcome"

2022 American Transplant Congress
Removing DSA and Region from Organ Allocation
R. R. Goff¹, A. R. Wilk¹, J. Foutz¹, A. Robinson¹, S. E. Booker¹, K. Bradbrook¹, T. Mupfudze¹, N. Turgeon², M. Cooper³, D. Klassen¹
¹United Network for Organ Sharing, Richmond, VA, ²University of Texas at Austin, Austin, TX, ³Medstar Georgetown, Washington , D.C., DC
*Purpose: Over the past 4 years, the OPTN has removed Donation Service Area (DSA) and OPTN Region from deceased donor organ allocation with the goal…
2022 American Transplant Congress
Real-Life Tacrolimus Levels Are Associated with Biopsy-Proven Acute Rejection After the First Year Post-Kidney Transplantation
S. Meziyerh, T. van Gelder, D. van der Helm, P. J. van der Boog, J. W. de Fijter, D. J. Moes, A. P. de Vries
LUMC, Leiden, Netherlands
*Purpose: Evidence to recommend specific target concentrations for immunosuppression beyond the first year of kidney transplantation (KT) is limited. We correlated real-life exposure data of…
2022 American Transplant Congress
Hypothermic Pulsatile Flush of Hepatitis C Virus (HCV) RNA Positive Kidney Reduces Viral Load
A. Jain¹, W. Greene²
¹Transplant Surgery, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, ²Dept. of Pathology, Penn State Health Milton S. Hershey Medical Center, Hershey, PA
*Purpose: Does Hypothermic pulsatile flush of hepatitis C virus (HCV) RNA positive kidney reduce the viral load?*Methods: Unutilized, HCV RNA-positive deceased donor kidneys were obtained…
2022 American Transplant Congress
Implications of Pre-Transplant (tx) COVID-19 on SOT or HCT: A Multicenter Study
G. Haidar¹, K. Hughes-Kramer², C. Alonso³, J. Hand⁴, E. Blodget⁵, V. Srinivasa⁵, S. Aslam⁶, H. Hassouna⁷, C. Lawson⁷, M. Malinis⁸, S. Anjan⁹, E. Lease¹⁰, M. Al-Obaidi¹¹, P. Vergidis¹², J. Husson¹³, D. van Duin¹⁴, R. Avery¹⁵, K. Downes¹⁶, M. R. Heldman¹⁰, J. Nelson¹⁷, S. Pouch¹⁸, S. Chuang¹⁹, C. Kao²⁰, M. Estabrook²¹, F. Alconchel²², S. Mazumber²³, P. Samanta², M. Wagener², N. Singh², F. Silveira²
¹UPitt, Pitt, PA, ²UPitt, Pittsburgh, PA, ³BIDMC, Boston, MA, ⁴Ochsner, New Orleans, LA, ⁵USC, Los Angeles, CA, ⁶UCSD, San Diego, CA, ⁷Spectrum Health, Grand Rapids, MI, ⁸Yale, New Haven, CT, ⁹UMiami, Miami, FL, ¹⁰UW, Seattle, WA, ¹¹U Arizona, Tucson, AZ, ¹²Mayo, Rochester, MN, ¹³UMMC, Baltimore, MD, ¹⁴UNC, Chapel Hill, NC, ¹⁵JHU, Baltimore, MD, ¹⁶CHOP, Philadelphia, PA, ¹⁷Stanford, Stanford, CA, ¹⁸Emory, Decatur, GA, ¹⁹U Rochester, Rochester, NY, ²⁰WashU, St Louis, MO, ²¹WashU, Saint Louis, MO, ²²Spain, Murcia, Spain, ²³U Tennessee, Memphis, TN
*Purpose: Describe outcomes of patients (pt) with pre-tx COVID-19.*Methods: Multicenter study of SOT/HCT candidates who had a positive (pos) SARS-CoV-2 PCR pre-tx.*Results: Pre-tx: Of 208…
2022 American Transplant Congress
Myeloid Molecular Signature of Ischemia-Reperfusion Injury in Human Liver Transplantation
R. A. Sosa¹, R. Ahn², A. Terry¹, Z. Qian², F. Li¹, S. Sen¹, T. Ito³, B. V. Naini¹, F. Kaldas³, A. Hoffmann², R. W. Busuttil³, D. W. Gjertson¹, J. Kupiec-Weglinski³, E. F. Reed¹
¹Pathology and Lab Medicine, UCLA, Los Angeles, CA, ²Microbiology, Immunology and Molecular Genetics, UCLA, Los Angeles, CA, ³Surgery, UCLA, Los Angeles, CA
*Purpose: Ischemia reperfusion injury (IRI) is well-appreciated as a significant clinical concern for recipients of liver transplantation, yet there are still no diagnostic or therapeutic…
2022 American Transplant Congress
Risk Factors Associated with ICU Admission and Death in Patients Hospitalized with COVID-19 Differ Between Solid Organ Transplant and Non-Solid Organ Transplant Patients
J. Schaenman, H. Byford, T. R. Grogan, Y. Motwani, O. Beaird, M. Kamath, E. Lum, K. Meneses, D. Sayah, D. Vucicevic, S. Saab
David Geffen School of Medicine at UCLA, Los Angeles, CA
*Purpose: Despite the large numbers of reports on patient risk factors for poor clinical outcomes with COVID-19, little is known about how these risks may…
2022 American Transplant Congress
Living Related Kidney Donation for Alternative Complement Pathway Diseases: Long-Term Outcomes
Y. Caliskan¹, S. Safak², A. B. Dirim², A. Velioglu³, B. Yelken⁴, O. A. Oto², A. Yildiz⁵, N. Garayeva², H. Yazici², A. Ersoy⁵, A. Turkmen⁴, K. L. Lentine¹
¹Saint Louis University, Saint Louis, MO, ²Istanbul University, Istanbul, Turkey, ³Marmara University, Istanbul, Turkey, ⁴Koc University Hospital, Istanbul, Turkey, ⁵Uludag University, Bursa, Turkey
*Purpose: Atypical hemolytic-uremic syndrome (aHUS) and C3 glomerulopathy (C3G) are rare conditions that cause severe kidney disease. Data to guide the evaluation of living related…
2022 American Transplant Congress
The Impact Of Monoclonal Antibody Against Sars-CoV2 And Vaccination On Outcomes In Kidney Transplant Recipients With Covid-19
N. M. Ali, V. Tatapudi, R. Chand, k. Sureau, S. Mehta, R. Montgomery
NYU Langone Transplant Institute, New York, NY
*Purpose: Solid organ transplant recipients are at high risk of morbidity and mortality from coronavirus disease 2019 (COVID-19) with mortality rates as high as 30%…
2022 American Transplant Congress
Transjugular Intrahepatic Portosystemic Shunt Placement is Associated with Increased All-Cause and Cardiac Mortality in Those Undergoing Liver Transplant for Nonalcoholic Steatohepatitis
D. U. Lee¹, J. Han², J. Kwon², K. Chang², G. Fan², K. Lee¹, N. Urrunaga³, C. Bhati¹, D. Maluf³, K. Shetty³
¹Department of Gastroenterology and Hepatology, University of Maryland, Baltimore, MD, ²Tufts Medical Center, Boston, MA, ³University of Maryland, Baltimore, MD
*Purpose: Since the effect of transjugular intrahepatic portosystemic shunt (TIPS) on post LT outcomes is not well understood, we undertook this analysis of a large…
2022 American Transplant Congress
Outcomes After Covid-19 Infection in Transplant Recipients
K. L. Freels¹, K. Saharia², J. Baddley², N. Costa³, S. Niederhaus⁴
¹University of Maryland School of Medicine, Baltimore, MD, ²Medicine, University of Maryland School of Medicine, Baltimore, MD, ³Medicine, Georgetown University, Washington, DC, ⁴Surgery, University of Maryland School of Medicine, Baltimore, MD
*Purpose: The purpose of this study is to evaluate outcomes of readmission, rejection, graft dysfunction, graft failure, and death in SOT recipients (SOTR) after COVID-19…