Articles tagged "Outcome"

2022 American Transplant Congress
Prolonged Preservation by Hypothermic Machine Perfusion Facilitates Logistics in Liver Transplantation: A European Observational Cohort Study
I. M. Brüggenwirth¹, M. Mueller², V. A. Lantinga¹, S. Camagni³, R. De Carlis⁴, L. De Carlis⁵, M. Colledan⁶, D. Dondossola⁷, M. Drefs⁸, J. Eden², D. Ghinolfi⁹, D. Koliogiannis¹⁰, G. Lurje¹¹, T. Manzia¹², D. Monbaliu¹³, P. Muisean¹⁴, D. Patrono¹⁵, J. Pratschke¹⁶, R. Romagnoli¹⁷, M. Rayar¹⁸, F. Roma¹⁴, A. Schlegel², P. Dutkowski², R. J. Porte¹, V. E. de Meijer¹
¹University Medical Center Groningen, Groningen, Netherlands, ²University Hospital Zurich, Zurich, Switzerland, ³ASST Papa Giovanni XXIII, Bergamo, Italy, ⁴ASST Grande Ospedale Metropolitano Niguarda, Niguarda, Italy, ⁵Niguarda Ca’ Granda Hospital, Niguarda, Italy, ⁶Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy, ⁷Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy, ⁸University of Munich, Munich, Germany, ⁹Azienda Ospedaliero Universitaria Pisana, Pisa, Italy, ¹⁰Hospital of the University of Munich, Munich, Germany, ¹¹Charité Universitätsmedizin Berlin, Berlin, Germany, ¹²Tor Vergata University, Rome, Italy, ¹³KU Leuven University Hospitals Leuven, Leuven, Belgium, ¹⁴Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy, ¹⁵A. O. U. Città della Salute e della Scienza di Torino, Turin, Italy, ¹⁶Charite Universitatsmedizin Berlin, Berlin, Germany, ¹⁷AOU Città della Salute e della Scienza di Torino, Turin, Italy, ¹⁸CHU Pontchaillou, Rennes, France
*Purpose: A short period (1-2 hours) of hypothermic oxygenated machine perfusion (HOPE) after static cold storage is safe and reduces ischemia-reperfusion injury-related complications after liver…
2022 American Transplant Congress
Reduction in Opioid Discharge Prescribing for Kidney Transplant Recipients Through Implementation of a Standardized Opioid Prescribing Policy
S. Fredrick¹, K. Dokus², J. Cooley¹, A. Dulen³, J. Melaragno¹
¹Pharmacy, University of Rochester Medical Center, Rochester, NY, ²Transplant Surgery, University of Rochester Medical Center, Rochester, NY, ³Wegmans School of Pharmacy, St. John Fisher College, Rochester, NY
*Purpose: Diversion of unused opioid medications has contributed to the opioid epidemic, and opioid use after kidney transplantation has been shown to be a risk…
2022 American Transplant Congress
Direct Procurement of Heart and Lungs from a Controlled DCD Donor with Ongoing Abdominal Normothermic Regional Perfusion (aNRP) – A Synchronized Retrieval
M. Husain¹, A. Jothidasan¹, C. Zeschky¹, M. Osman², M. Berman², R. Gaurav³, A. Butler³, C. Watson³, B. Stutchfield⁴, I. Currie⁵, G. Oniscu⁵, J. Dunning¹, U. Stock¹
¹Department of Cardiothoracic Surgery, Transplantation and MCS, Royal Brompton & Harefield Hospitals Part of Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom, ²Department of Heart and Lung Transplant, Royal Papworth Hospital, Cambridge, United Kingdom, ³Roy Calne Transplant Unit, Department of Surgery, Addenbrookes Hospital, Cambridge University NHS Trust, Cambridge, United Kingdom, ⁴Edinburgh Transplant Centre, Royal Infirmary of Edinburgh, Edinburgh, Edinburgh, United Kingdom, ⁵Edinburgh Transplant Centre, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom
*Purpose: With the increased number of aNRP in controlled DCD donors comes a high demand for techniques to directly procure cardiothoracic organs during the aNRP.…
2022 American Transplant Congress
Increased Risk for Allograft Loss in African American Kidney Transplant Recipients After Biopsy for Chronic Allograft Dysfunction
C. R. Dorr¹, B. Wu², B. Guo², W. Guan², D. Schladt¹, S. Elmer¹, G. Crary³, G. Onyeaghala¹, W. Oetting², G. Agarwal⁴, R. B. Mannon⁵, P. Jacobson², A. Matas², A. Israni³
¹Hennepin Healthcare Research Institute, Minneapolis, MN, ²University of Minnesota, Minneapolis, MN, ³Hennepin County Medical Center, Minneapolis, MN, ⁴University of Alabama at Birmingham, Birmingham, AL, ⁵Medicine, University of Nebraska Medical Center, Omaha, NE
*Purpose: Chronic allograft dysfunction (CGD) is the first sign of a “troubled kidney”. CGD was defined as >25% increase in serum creatinine relative to a…
2022 American Transplant Congress
Characteristics and Outcomes of Anhepatic Patients Listed for Liver Retransplantation
R. G. Kathawate¹, T. Ibeabuchi², P. Abt², T. Bittermann²
¹University of Michigan, Ann Arbor, MI, ²University of Pennsylvania, Philadelphia, PA
*Purpose: The frequency and outcomes of anhepatic patients listed for transplantation in the United States has not been previously described. The United Network for Organ…
2022 American Transplant Congress
Impaired Left Ventricular Global Longitudinal Strain: Clinical Presentation and Outcomes in Liver Transplantation Recipients without Arrhythmia or Structural Heart Disease
M. B. Hammami, J. Grossman, P. Xue, H. Allaham, K. Eagan, S. Gottlieb, C. Hong, L. Wang, C. Bhati, D. Maluf, K. Shetty, N. Urrunaga
University of Maryland School of Medicine, Baltimore, MD
*Purpose: Assess the prevalence and characteristics of patients without arrhythmia or structural heart disease (SHD) but with impaired pre-transplant left ventricular global longitudinal strain (GLS)…
2022 American Transplant Congress
Physiological Age by Artificial Intelligence-Enhanced Electrograms as a Novel Biomarker of Mortality in Kidney Transplant Candidates
E. Lorenz, I. Zaniletti, B. Johnson, T. Petterson, W. Kremers, C. Schinstock, H. Amer, A. Cheville, N. LeBrasseur, A. Baez-Suarez, Z. Attia, F. Lopez-Jimenez, P. Friedman, C. Kennedy, A. Rule
Mayo Clinic, Rochester, MN
*Purpose: Assessing mortality risk prior to kidney transplantation is challenging. Age-Gap, which is the difference between physiological age determined by artificial intelligence-enhanced electrocardiograms (ECG) and…
2022 American Transplant Congress
Role of Vaccination in the COVID-19 Nationwide Cohort (N3C) of Solid Organ Transplant Recipients
A. J. Vinson¹, A. Anzalone², R. Dai², E. French³, A. Olex³, J. Sun⁴, G. Agarwal⁵, S. Lee⁶, R. B. Mannon⁷
¹Nova Scotia Health Authority, Halifax, NS, Canada, ²University of Nebraska Medical Center, Omaha, NE, ³Wright Center for Clinical and Translational Research, Richmond, VA, ⁴Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, ⁵University of Alabama at Birmingham, Birmingham, AL, ⁶University of Saskatchewan, Regina, SK, Canada, ⁷Medicine, University of Nebraska Medical Center, Omaha, NE
*Purpose: Immunosuppressed solid organ transplant (SOT) patients have been repeatedly challenged in the COVID-19 pandemic with significant morbidities and mortality following infection and a suppressed…
2022 American Transplant Congress
A Intention-to-Treat Analysis of 881 Consecutively Waitlisted Patients to Develop a Survival Benefit Model for Hepatocellular Carcinoma Liver Transplant Candidates
B. V. Tran¹, W. Lapisatepun¹, W. Dumronggittigule¹, D. Markovic², Y. Lee¹, F. Kaldas¹, D. Farmer¹, R. Busuttil¹, V. Agopian¹
¹Department of Surgery, University of California Los Angeles, Los Angeles, CA, ²Department of Medicine, Statistics Core, University of California Los Angeles, Los Angeles, CA
*Purpose: The current liver transplantation (LT) selection paradigm for hepatocellular carcinoma (HCC) patients ignores the variable risks of waitlist dropout and post-LT recurrence/death, with the…
2022 American Transplant Congress
Simultaneous Liver and Kidney Transplantation and Gender Disparities in Transplant Access and Outcomes
G. Peschard¹, M. Wang², Y. Al-Hosni³, K. Lentine⁴, S. Chang², T. Alhamad⁵
¹Nephrology, UCSF, San Francisco, CA, ²Division of Public Health Sciences, Department of Surgery, Washington University in St Louis, Saint Louis, MO, ³Division of General Medical Sciences, Washington University in St Louis, Saint Louis, MO, ⁴Saint Louis University Center for Abdominal Transplantation,, Saint Louis University, Saint Louis, MO, ⁵Nephrology, Washington University in St Louis, St Louis, MO
*Purpose: The frequency of simultaneous liver-kidney transplantation (SLKT) has been rising since the implementation of the Model for End-stage Liver Disease (MELD)-liver allocation system in…