Articles tagged "Organ Selection/Allocation"

2022 American Transplant Congress
Donor-Derived Carbapenem-Resistant Gram-Negative Infections: Risk Mitigation Strategy in Solid Organ Transplant Improves Recipients Safety and Could Expand Donor Pool
A. Mularoni¹, E. Graziano¹, M. Campanella¹, A. Cervo², M. Peghin³, F. Barbera¹, P. Conaldi¹, A. Luca¹, P. A. Grossi⁴
¹ISMETT, Palermo, Italy, ²Department of Infectious Diseases, Azienda Ospedaliero-Universitaria Policlinico of Modena, Modena, Italy, ³Division of Infectious Diseases, ASUFC, Udine, Italy, ⁴Infectious and Tropical Diseases Unit, University of Insubria, Varese, Italy
*Purpose: We implemented an Active Surveillance System (ASS) to mitigate the risk of unexpected carbapenem-resistant Gram-negative (CRGN) donor-derived infection (DDI) in solid organ transplant recipient…
2022 American Transplant Congress
Prospective Study of Preimplantation Biopsy in Deceased Donor Kidney Transplantation (DDKT)
H. Me, M. Smith, C. Jadlowiec, K. Harris, R. Butterfield, H. Khamash, B. G. AbuJawdeh, K. Reddy, R. Heilman
Mayo Clinic, Phoenix, AZ
*Purpose: Our aim was to study the impact of preimplantation biopsy (Bx) findings in selecting kidneys from more marginal donors.*Methods: This is a 2-year prospective…
2022 American Transplant Congress
Myeloid Molecular Signature of Ischemia-Reperfusion Injury in Human Liver Transplantation
R. A. Sosa¹, R. Ahn², A. Terry¹, Z. Qian², F. Li¹, S. Sen¹, T. Ito³, B. V. Naini¹, F. Kaldas³, A. Hoffmann², R. W. Busuttil³, D. W. Gjertson¹, J. Kupiec-Weglinski³, E. F. Reed¹
¹Pathology and Lab Medicine, UCLA, Los Angeles, CA, ²Microbiology, Immunology and Molecular Genetics, UCLA, Los Angeles, CA, ³Surgery, UCLA, Los Angeles, CA
*Purpose: Ischemia reperfusion injury (IRI) is well-appreciated as a significant clinical concern for recipients of liver transplantation, yet there are still no diagnostic or therapeutic…
2022 American Transplant Congress
Size to Fit: A Simple Formula to Predict Donor Liver Weight in Deceased Donor Liver Transplant
A. Mohamed¹, J. Cui², T. Kitajima¹, T. Shamaa¹, T. Ivanics¹, I. Godana³, A. Yorks², S. Shimada¹, B. Madek¹, M. Rizzari¹, A. Yoshida¹, M. Abouljoud¹, S. Nagai¹, K. Collins¹
¹Henry Ford Transplant Institute, Detroit, MI, ²Wayne State University School of Medicine, Detroit, MI, ³General Surgery, McLaren, Lansing, MI
*Purpose: Estimated donor liver volume (DLV) prediction equations are widely published. However, they often are complex and underpredict DLV, particularly in non-ideal body weight donors.…
2022 American Transplant Congress
Outcomes of Kidney Transplantation from a Male Donor with a Highly Elevated Prostate Specific Antigen Level (PSA) in Female Recipients
S. K. Patel, E. Siskind, M. Jaleco, S. Shah, A. Adekile, S. Nijim, M. Laftavi
Center for Transplantation, University Medical Center of Southern Nevada, Las Vegas, NV
*Purpose: Donor derived malignancy is a contraindication for kidney transplantation. Published literature is devoid of instances of utilization of organs from donors with high PSA…
2022 American Transplant Congress
ABO Hemagglutination Titres Do Not Accurately Reflect ABO Antibody Levels
A. Halpin¹, T. Ellis², J. Pearcey², B. Motyka², T. L. Lowary³, C. Cairo⁴, S. Maier², L. J. West⁵
¹Pediatrics/Dept of Laboratory Medicine, University of Alberta/Alberta Precision Laboratories, Edmonton, AB, Canada, ²Pediatrics, University of Alberta, Edmonton, AB, Canada, ³Academia Sinica, Institute of Biological Chemistry, Taipei, Taiwan, ⁴Chemistry, University of Alberta, Edmonton, AB, Canada, ⁵Pediatrics, University of Alberta, Canadian Donation and Transplant Research Program, Edmonton, AB, Canada
*Purpose: ABO antibody (ABO-Ab) quantification is essential for risk assessment for ABO-incompatible (ABOi) transplantation, but the hemagglutination assay (HA) for ABO-Ab titres is known to…
2022 American Transplant Congress
Miami Protocol for Liver Deceased Donors After Circulatory Death: Increased 1-year Overall Survival for Selected Patients
V. Venkatasamy, P. Abreu, J. Riella, R. Miyashiro, A. Tector, A. Tekin, G. Selvaggi, R. Vianna
University of Miami, Jackson Memorial Hospital, Miami Transplant Institute, Miami, FL
*Purpose: The use of deceased donors after circulatory death (DCD) for liver transplantation (LT) is still underutilized. It provides an acceptable solution to increase the…
2022 American Transplant Congress
Assessing Safety of Using ECMO-Supported Donors in Abdominal Transplantation
P. J. Altshuler¹, A. P. Shah¹, J. M. Glorioso¹, W. R. Maley¹, A. M. Frank¹, C. B. Ramirez¹, H. Dang¹, S. West², R. Hasz, Jr.², A. S. Bodzin¹
¹Department of Surgery, Thomas Jefferson University, Philadelphia, PA, ²Gift Of Life Donor Program, Philadelphia, PA
*Purpose: Organ donors supported by extracorporeal membrane oxygenation (ECMO) are historically considered high-risk and are judiciously utilized. Here we explore the safety of using organs…
2022 American Transplant Congress
Kidney Allocation System Promotes Racial Equality Not Equity in Access to Deceased Donor Kidney Transplantation
C. Killian¹, B. Shelton¹, P. MacLennan¹, M. McLeod¹, A. Carter¹, R. Reed¹, H. Qu¹, B. Orandi¹, V. Kumar¹, D. Sawinski², J. Locke¹
¹University of Alabama at Birmingham, Birmingham, AL, ²Weill Cornell Medical College, New York City, NY
*Purpose: While the 2014 Kidney Allocation System (KAS) reduced deceased donor kidney transplant (DDKT) racial disparities, candidates’ community-level vulnerability has not been considered. The purpose…
2022 American Transplant Congress
Can We Predict Progression of Potential Donation After Cardiac Death Donors (DCD) Using DonorNet?
Y. Bababekov¹, A. Yule¹, H. Moore¹, R. Choudhury², C. Hertert³, T. Pshak⁴, T. Nydam⁵, B. Kaplan¹, E. Pomfret¹, J. Pomposelli⁵
¹Transplant Surgery, University of Colorado, Aurora, CO, ²University of Colorado Hospital, Denver, CO, ³Donor Alliance, Denver, CO, ⁴University of Colorado, Denver, CO, ⁵University of Colorado, Aurora, CO
*Purpose: DCD utilization of livers is limited by unpredictability of progression, perceived worse outcome, and costs related to deployment of resources. We aimed to predict…

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