ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Obesity"

  • 2016 American Transplant Congress

    Muscle Function, Mass, and Quality in Obese Liver Transplant Candidates: Results from the Functional Assessment in Liver Transplantation (FrAILT) Study.

    C. Wang, I. Lobach, J. Lai.

    UCSF, San Francisco, CA.

    Background: Sarcopenia, or severe loss of muscle mass, is common in cirrhotics and adversely affects quality of life and transplant outcomes. Obese liver transplant(LT) candidates…
  • 2016 American Transplant Congress

    Bile Acid Signaling Affects Metabolism and Prolongs Allograft Survival in Obese Recipients.

    M. Quante, A. ElKhal, M. Seyda, J. Schuitenmaker, H. Uehara, S. Tullius.

    Division of Transplant Surgery & Transplant Surgery Research Laboratory, Brigham and Women's Hospital / Harvard Medical School, Boston, MA.

    Although obesity has been linked to impaired transplant outcomes, underlying mechanisms and consequences of obesity on alloimmunity are only poorly understood.Allogenic skin transplantations were performed…
  • 2016 American Transplant Congress

    Pre-Transplant Bariatric Surgery and One-Year Graft Loss Risk in Kidney Transplants.

    G. Mour, J. Zhang, Z. Su, D. Taber, P. Mauldin, T. Srinivas.

    MUSC, Charleston.

    Background: Several centers recommend bariatric surgery (BS) pre-transplantation (pre-Tx) with arbitrary BMI cutoffs. The effects of BS on Tx outcome are unclear. We studied the…
  • 2016 American Transplant Congress

    Renal Transplant in Obese Recipients: Consideration of Donor and Recipient Factors Can Improve Outcomes.

    P. Stahler, J. Mezrich, G. Leverson, D. Kaufman, H. Sollinger.

    Division of Transplantation, University of Wisconsin-Madison, Madison, WI.

    Background: Obesity rates in the transplant population are increasing. Previous studies are limited by small sample sizes, short-term follow up, and conflicting results. Factors including…
  • 2016 American Transplant Congress

    The Impact of Body Mass Index > 35 on Kidney Transplant Outcomes: A Systematic Review.

    D. Walczak, E. Benedetti.

    Organ Transplant, University of Illinois Hospital and Health Sciences System, Chicago, IL.

    Background: The increased prevalence of obesity (BMI > 30) among adults in the United States over the last two decades is reflected in the number…
  • 2016 American Transplant Congress

    The Role of Obesity in Survival Outcomes of Liver Transplant Recipients with High MELD Score.

    S.-H. Chang,1 N. Carlsson,1 X. Liu,2 J. Wellen,3 J. Hagopian,4 T. Horwedel,4 T. Alhamad.5

    1Division of Public Health Sciences, Department of Surgery, Washington University in St. Louis, St. Louis; 2Division of Biostatistics, Washington University in St. Louis, St. Louis; 3Department of Surgery, Washington University in St. Louis, St. Louis; 4Department of Pharmacy, Barnes Jewish Hospital, St. Louis; 5Renal Division, Washington University, St. Louis.

    Background:Obesity has become an epidemic in the United States. More than one third of adults are obese, defined as having body mass index (BMI) greater…
  • 2016 American Transplant Congress

    Resolution of Donor Non-Alcoholic Fatty Liver Disease Following Liver Transplantation.

    A. Posner,1 W. Twaddell,2 S. Hanish,2 D. Bruno,2 W. Hutson,2 L. Hebert,2 R. Barth,2 J. LaMattina.2

    1University of Maryland School of Medicine, Baltimore, MD; 2Division of Transplantation, University of Maryland School of Medicine, Baltimore, MD.

    Purpose: Severe and moderate degrees of donor liver steatosis have traditionally limited the transplantation of these organs. The natural history of successfully transplanted livers with…
  • 2015 American Transplant Congress

    Risk of ESRD Attributable to Live Kidney Donation in Various Subgroups of Donors

    A. Muzaale, A. Massie, D. Segev.

    Johns Hopkins University, Baltimore, MD.

    Risk of ESRD attributable to live donation in male, older, obese, related donors, and donors with high predonation eGFR remains uncharacterized.Methods: Various subgroups of individuals…
  • 2015 American Transplant Congress

    Activated Protein C Treatment Protects Steatotic and Non-Steatotic Livers Under Ischemia–Reperfusion Injury in Different Manner

    A. Matsuda, N. Kuriyama, H. Kato, Y. Azumi, M. Kishiwada, S. Mizuno, M. Usui, S. Isaji.

    Hepatobiliary Pancreatic and Transplant Surgery, Mie University Graduate School of Medicine, Tsu, Mie, Japan.

    Activated protein C (APC) is known to have the cytoprotective effect on liver ischemia–reperfusion injury (IRI) in rat models. However, it is unclear that whether…
  • 2015 American Transplant Congress

    Bariatric Surgery Prolongs Allograft Survival by Promoting Th2 Conditions

    M. Quante, A. ElKhal, H. Rodriguez, R. Abdi, F. Krenzien, H. Uehara, S. Tullius.

    Division of Transplant Surgery and Transplant Surgery Research Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston.

    Background: Obesity is linked to chronic low-grade inflammation. We hypothesized that I) obesity will accelerate allograft rejection linked to pro-inflammatory immune responses and that II)…
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