ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "non-heart-beating"

  • 2017 American Transplant Congress

    Kidney Re-Transplantation (KRTx) from Donation After Cardiocirculatory Death (DCD)-Standard Criteria Donors (SCD).

    M. Khan, B. Alradawna, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, A. Palanisamy, M. Gautreaux, W. Doares, S. Kaczmorsky, R. Stratta.

    Transplant, Wake Forest Baptist Medical Center, Winston Salem, NC

    Donation after cardiac death (DCD) donor kidneys increase the organ pool but use in kidney retransplantation (KRTx) has been questioned due to higher rates of…
  • 2017 American Transplant Congress

    Prophylactic Therapy Against Multidrug-Resistant Acinetobacter baumannii Contamination of Preservation Solution in Renal Transplantation: A Single Center Experience.

    R. Wang, J. Zhou, J. Wu.

    Kidney Disease Center, the First Affiliated Hospital, Zhejiang University, Hangzhou, China

    Objectives: Rapidly increased multiple drug resistant (MDR) gram negative bacilli like Acinetobacter baumannii (AB) become the main pathogen in ICU nowdays. Our study is intended…
  • 2017 American Transplant Congress

    Normothermic Regional Perfusion of Donors Following Circulatory Death Improves Outcomes in Liver Transplantation.

    E. Mowlem,1 L. Randle,2 C. Fear,1 K. Crick,1 S. Messer,4 S. Large,4 A. Butler,3 C. Watson.3

    1Cambridge Transplant Unit, Addenbrookes Hospital, Cambridge, United Kingdom; 2OrganOx Ltd, Oxford, United Kingdom; 3Dept of Surgery, University of Cambridge, Cambridge, United Kingdom; 4Papworth Hospital, Cambridge, United Kingdom

    Introduction: Donation after Circulatory Death (DCD) provides 23% of UK livers for transplantation, but such transplants are associated with more primary graft function and early…
  • 2017 American Transplant Congress

    The Performance of Four Tools for the Prediction of Potential for Organ Donation After Cardiac Death in Neurocritical Patients: A Prospective, Multicenter, Observational Study.

    Z. Guo,1 G. Xu,1 P. Schroder,2 M. Manyalich,3 X. He,1 G. Chen.1

    1Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; 2Department of Surgery, Duke University Medical Center, Durham; 3Transplant Procurement Management-Donation & Transplantation institute Foundation, Barcelona, Spain

    Background Successful donation after circulatory death (DCD) requires identification of patients dieing within limited time after withdrawal of life-sustaining treatment (WLST). We aimed to compare…
  • 2017 American Transplant Congress

    A Humanized Anti-CD47 Monoclonal Antibody Therapy Alleviates Ischemia-Reperfusion Injury of Porcine Renal Allografts Donated After Cardiac Death.

    M. Xu,1 B. Banan,1 X. Wang,1 D. Chirumbole,1 B. Rabe,1 S. Garcia-Aroz,1 D. Nayak,1 Z. Zhang,1 J. Jia,1 G. Upadhya,1 J. Gaut,2 P. Manning,3 Y. Lin,1 W. Chapman.1

    1Department of Surgery, Washington University School of Medicine, St. Louis; 2Department of Pathology and Immunology, Washington University School of Medicine, St. Louis; 3Tioma Therapeutics, Inc, St. Louis

    PURPOSE: This study investigated whether the blockade of the CD47 signaling pathway, which is involved in vascular endothelial nitric oxide regulation, reduces ischemia-reperfusion injury (IRI)…
  • 2017 American Transplant Congress

    A Novel Technique to Increase Donor Utilization: Our Experience Using High-Dose Tissue Plasminogen Activator Flush in Donation-After-Cardiac-Death Donors for Liver Transplantation.

    J. Graham, K. Lorenzen, S. Bellemare, M. Kinkhabwala, J. Rocca.

    Surgery, Montefiore Medical Center, Bronx, NY

    The utilization of donation-after-cardiac-death (DCD) livers remains generally low. Strategies to address the perceived liabilities associated with DCD organs could influence their utilization in a…
  • 2017 American Transplant Congress

    CD47 Blockade Reduces Ischemia/Reperfusion Injury in Donation After Cardiac Death Rat Kidney Transplantation.

    X. Wang,1 M. Xu,1 J. Jia,1 Z. Zhang,1 J. Gaut,2 G. Upadhya,1 P. Manning,3 Y. Lin,1 W. Chapman.1

    1Department of Surgery, Washington University School of Medicine, Saint Louis; 2Pathology and Immunology, Washington University School of Medicine, Saint Louis; 3Tioma Therapeutics, Saint Louis

    Purpose: We evaluated the potential effects of antibody-mediated CD47 blockade to modulate vascular endothelial nitric oxide activity and reduce ischemia reperfusion injury in a rat…
  • 2017 American Transplant Congress

    Implementing a Successful DCD Heart Programme to the United Kingdom.

    M. Ryan, S. Duncalf.

    Organ Donation and Transplantation, NHS Blood and Transplant, Bristol, United Kingdom

    The UK has the most successful DCD heart programme in the world which has primarily been developed in one region in England. Due to a…
  • 2016 American Transplant Congress

    Does Location Matter for Withdrawal of Donation After Cardiac Death Donors ?

    K. Mekeel,1 W. Garrison,2 J. Trageser,2 J. Berumen,1 L. Stocks,2 A. Hemming.1

    1Surgery, University of California-San Diego, La Jolla, CA; 2Lifesharing, San Diego, CA.

    Purpose: Withdrawal for DCD donors traditionally occurs in the OR. Families often refuse to proceed with DCD donation if they are unable to be present…
  • 2016 American Transplant Congress

    Controlled Cardiac Death Donor Program for Kidney Transplantation – Spanish Multicenter Experience with Two Years of Follow-Up.

    J. Portoles,1 M. Perez-Saez,2 D. Hernandez-Marrero,2 O. Lafuente,1 F. Diekmann,2 N. Maruri Kareaga,2 M. Rodriguez-Ferrero,2 F. Llamas,2 M. Mazuecos,2 J. Juega,2 E. Melilli,2 A. Rodriguez-Benot,2 A. Alonso,2 J. Pascual.2

    1Nephrology, U.H.Puerta de Hierro-RedinRen, Majadahonda, Spain; 2Nephrology, SENTRA-GEODAS Group, Madrid, Spain.

    Background: Controlled donation after cardiac death (cDCD) programs are running in several countries for years. National transplant organization (ONT) has developed a nation-wide program in…
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