Articles tagged "non-heart-beating"

2016 American Transplant Congress
Effect of Modifying Life Support Withdrawal Practices on Outcomes of Donation After Circulatory Death in Liver Transplantation: A Meta-Analysis.
Y. Cao,^1,2 S. Shahrestani,³ H. Chew,^2,4 M. Crawford,⁵ P. Macdonald,^1,2,4 J. Laurence,^3,5,7 W. Hawthorne,^3,6 K. Dhital,^1,2,4 H. Pleass.^3,5,6
¹Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia; ²Victor Chang Cardiac Research Institute, Sydney, NSW, Australia; ³Sydney Medical School, University of Sydney, Sydney, NSW, Australia; ⁴Cardiac Transplant Unit, St. Vincent's Hospital, Sydney, NSW, Australia; ⁵Australian National Liver Transplant Unit, Royal Prince Alfred Hospital, Sydney, NSW, Australia; ⁶The Department of Surgery, Westmead Hospital, Sydney, NSW, Australia; ⁷Institute of Academic Surgery, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Aim. Donor warm ischaemic time is identified as the main risk factor for poor outcomes in liver transplantation using donation after circulatory death (DCD) compared…
2016 American Transplant Congress
Persufflation Improves Viability and Function of Porcine Kidneys Relative to Static Cold Storage.
C. Min,¹ L. Steyn,² A. Pandey,³ R. Harland,² J.-P. Galons,⁴ K. Papas.²
¹Physiology, University of Arizona, Tucson, AZ; ²Surgery, University of Arizona, Tucson, AZ; ³Electrical and Chemical Engineering, University of Arizona, Tucson, AZ; ⁴Medical Imaging, University of Arizona, Tucson, AZ.
The use of marginal organs demands optimization of organ storage and quality assessments prior to transplantation. Organs from donors after cardiac death (DCD) are exposed…
2016 American Transplant Congress
Acute Kidney Injury and Chronic Kidney Disease in Donation After Circulatory Death Liver Transplantation: UK Single Centre Study.
I. Umbro,^1,2 F. Tinti,^1,2 F. Evison,³ A. Sharif,⁴ B. Gunson,⁵ A. Mitterhofer,² J. Ferguson,¹ P. Muiesan.¹
¹The Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom; ²Nephrology and Dialysis Unit, Sapienza University of Rome, Rome, Italy; ³Department of Health Informatics, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom; ⁴Department of Nephrology and Transplantation, Queen Elizabeth Hospital, Birmingham, United Kingdom; ⁵NIHR Birmingham Liver Biomedical Research Unit and Centre for Liver Research, University of Birmingham, Birmingham, United Kingdom.
Aim of the study is to assess the incidence of acute kidney injury (AKI) and chronic kidney disease (CKD) after liver transplantation (LT) in DCD…
2015 American Transplant Congress
Kidney Transplantation Using Kidneys from Donation After Circulatory Death Donors: Results from the UK Experience
D. Summers,^1,2,3 R. Johnson,² D. Collett,² C. Watson,^1,3 J. Neuberger,² G. Pettigrew,^1,3 J. Bradley.^1,3
¹Department of Surgery, Cambridge University, Cambridge, United Kingdom; ²Organ Donation and Transplantation, NHS Blood and Transplant, Bristol, United Kingdom; ³Cambridge NIHR Biomedical Reseach Centre, Cambridge, United Kingdom.
Introduction: Kidneys from donation after circulatory-death donors currently make up over 40% of deceased donor kidney transplants in the UK. In addition, 34% of deceased…
2015 American Transplant Congress
Parameters of Machine Perfusion Evaluating Quality of Kidneys from DCD/ECD Donors
G. Chen, C. Wang, J. Qiu, M. Han, X. He, L. Chen.
Organ Transplant Center, The first affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Background Donors from donation after cardiac death(DCD) and expanded criteria donors(ECD) have poorer outcomes compared to standard deceased donors(SCD). It is important to evaluate quality…
2015 American Transplant Congress
Risk Associated With DCD Kidney Transplantation Varies by Donor Characteristics
X. Luo, A. Massie, E. Chow, D. Segev.
Johns Hopkins, Baltimore.
Studies have shown that comparable kidney graft survival between donors after brain death (DBD) and donors after circulatory death (DCD) overall. However, the differential risk…
2015 American Transplant Congress
Causes of Poor Renal Function of Kidney Transplants from Uncontrolled Donation After Cardiac Death Donors (UDCDD)
M. Molina, E. González, E. Gutiérrez, E. Morales, E. Hernández, A. Sevillano, N. Polanco, J. Cabrera, M. Praga, A. Andres.
Nephrology, Hospital 12 de Octubre, Madrid, Spain.
INTRODUCTION: Kidneys grafts from UDCDD have higher ischemia injury. It develops in higher primary non function, lower graft survival and worst renal function compared to…
2015 American Transplant Congress
Hypothermic Machine Perfusion Improves Kidney Viability through Amelioration of Vasospasm and Edema of Podocytes and Renal Tubular Epithelial Cells
Z. Zhong,¹ Z. Liu,¹ Z. Fu,² Y. Zhang,² D. Ko,³ Y. Wang,¹ Q. Ye.^1,2
¹Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Hubei Key Laboratory of Medical Technology on Transplantation, Wuhan, China; ²The 3rd Xiangya Hospital of Central South University, Research Center of National Health Ministry on Transplantation Medicine Engineering and Technology, Changsha, Hunan, China; ³Massachusetts General Hospital, Department of Urology, Boston, MA.
Hypothermic machine perfusion (MP) may improve outcome after transplantation from donors after cardiac death (DCD) kidneys, but protective mechanisms of MP remain largely unknown. To…
2015 American Transplant Congress
National Outcomes of Donation After Cardiac Death (DCD) Liver Transplantation Are Equivalent to Donation After Brain Death (DBD) Liver Transplantation Using Older (DBD) Donor Livers
R. Redfield, M. Rizzari, J. Scalea, L. Fernandez, A. D'Alessandro, J. Mezrich, D. Foley.
University of Wisconsin, Madison, WI.
Background: Multiple studies have demonstrated that outcomes of DCD liver transplantation (LTx) are inferior to DBD LTx. Thus DCD liver transplantation represents only 7% of…
2015 American Transplant Congress
When Do DCD Donors Die? Outcomes and Implications of DCD at a High-Volume, Single-Center OPO in the United States
J. Scalea,¹ R. Redfield,¹ M. Rizzari,¹ R. Bennett,² J. Anderson,² M. Anderson,² D. Kaufman,¹ H. Sollinger,¹ L. Fernandez,^1,2 A. D'Alessandro,^1,2 J. Mezrich.¹
¹Division of Transplantation, Dept. of Surgery, University of Wisconsin, Madison, WI; ²Organ Recovery, UW Organ and Tissue Donation, Madison, WI.
Introduction: Successful donation (SD) is not always possible following attempted donation after circulatory death (DCD). The goal of this study was to determine the fate…