ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "non-heart-beating"

  • 2016 American Transplant Congress

    Hydrogen Sulfide Supplementation Helps Mitigate Effects of Ischemia Reperfusion Injury in a Murine Model of Donation After Cardiac Death Renal Transplantation.

    J. Grewal,1 I. Lobb,1 M. Saha,2 J. Jiang,2 A. Haig,1 A. Sener.1,2

    1Microbiology & Immunology, University of Western Ontario, London, Canada; 2Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, Canada.

    Donation after cardiac death(DCD) renal grafts experience a combination of prolonged warm and cold ischemia leading to greater ischemia reperfusion injury(IRI) that results in higher…
  • 2016 American Transplant Congress

    Deceased Organ Donors with Zero Organs Transplanted: Why and How Can We Improve?

    P. Lange,1 S. Rudich,1 N. Obaseki,1 J. Punch.2

    1Medical Division, Gift of Life Michigan, Ann Arbor, MI; 2Surgery, University of Michigan, Ann Arbor, MI.

    Organ recovery professionals and donor hospitals are under intense pressure to go to whatever lengths necessary to provide transplantable organs. However, such a mentality can…
  • 2016 American Transplant Congress

    Hypothermic Machine Perfusion Ameliorates Vasospasm and Edema of Podocytes and Renal Tubular Epithelial Cells Through Upregulating Expression of Krüppel-Like Factors 2.

    Z. Zhong,1 D. Ko,2 Y. Wang,1 Q. Ye.1

    1Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Wuhan, Hubei, China; 2Massachusetts General Hospital, Department of Urology, Harvard Medical School, Boston, MA.

    Protective mechanisms of hypothermic machine perfusion (MP) remain largely unknown. Vascular branches of the renal arteries of 6 kidneys in 320 donors were unexpectedly injured…
  • 2015 American Transplant Congress

    A 10 Min “No-Touch” Time – Is It Enough in DCD? A DCD Animal Study

    M. Sereinigg,1 V. Stadlbauer,2 T. Seifert-Held,3 F. Iberer,1 P. Stiegler.1

    1Department for Transplant Surgery, Medical University Graz, Graz, Austria; 2Department for Gastroenterology and Hepatology, Medical University Graz, Graz, Austria; 3Department for Neurology, Medical University Graz, Graz, Austria.

    Introduction: DCD is under investigation due to the lack of human donor organs. Required times of cardiac arrest vary between 75 seconds and 27 min…
  • 2015 American Transplant Congress

    Liver Transplantation in Children Using Organ Donation After Circulatory Death– An Analysis of the National Registry

    G. El-Gazzaz, K. Hashimoto, M. Fujiki, T. Daigo, C. Quintino, F. Aucejo, D. Kelly, C. Winans, C. Miller, J. Fung, B. Eghtesad.

    Liver Transplant and Hepatobiliary, Cleveland, Cleveland, OH.

    The waiting list mortality rate for children is higher than for adults owing to scarce availability of size-appropriate grafts for liver transplantation(OLT). There is a…
  • 2015 American Transplant Congress

    Patients Referred to an OPO: Analysis of Potential for Additional DCD Donors

    D. Bloomberg, J. Lewis, N. Benavides, M. James, H. Irving, A. Friedman.

    New York Organ Donor Network, New York, NY.

    Performance improvement at our organ procurement organization (OPO) includes retrospective analysis of the triage process for newly referred patients to identify missed opportunities for donation…
  • 2015 American Transplant Congress

    Impact of Donor Post-Extubation O2 Delivery on Recipient Hypoxic Cholangiopathy in Donation After Circulatory Death Liver Transplantation: The University of Colorado Experience

    T. Chirichella,1 C. Dunham,2 M. Zimmerman,4 K. Conzen,1 S. Kelley,3 E. Phelan,1 T. Steinberg,1 T. Nydam,1 T. Bak,1 I. Kam,1 M. Wachs.1

    1Transplant Surgery, University of Colorado Hospital, Aurora, CO; 2Department of Surgery, St. Elizabeth Health Center, Youngstown, OH; 3Donor Alliance Organ Procurement Organization, Denver, CO; 4Transplant Surgery, Medical College of Wisconsin, Milwaukee, WI.

    The critical shortage of deceased organ donors has led to increased utilization of DCD liver grafts. The purpose of this study was to evaluate DCD…
  • 2015 American Transplant Congress

    Longitudinal eGFR Modelling to Understand Rates of eGFR Decline in Renal Transplantation in the United Kingdom

    R. Pruthi,1 A. Casula,1 R. Hilton,2 R. Ravanan,3 P. Roderick,4 I. Macphee.5

    1UK Renal Registry, Bristol, United Kingdom; 2Guys Hospital, London, United Kingdom; 3Southmead Hospital, Bristol, United Kingdom; 4Southampton University, Southampton, United Kingdom; 5St Georges Hospital, London, United Kingdom.

    Background: The rate of decline in eGFR (slope) has been independently associated with a higher risk of cardiovascular events and all cause mortality in kidney…
  • 2015 American Transplant Congress

    Donor Hemodynamic Profile Presages Graft Survival in Donation After Cardiac Death Liver Transplantation

    M. Ertreo, C. Desai, R. Girlanda, T. Frias, T. Fishbein.

    Transplant Institute, Georgetown University Hospital, Washington, DC.

    IntroductionDonation after cardiac death (DCD) grafts are prone to periods of prolonged hypoxemia and hypotension prior to donor expiration, leading to an increased complication rate,…
  • 2015 American Transplant Congress

    Assessment of Actual Pediatric Organ Donation Potential: Neurologic and Circulatory Determination of Death at a Children's Hospital

    C. Aguayo,1 E. Bennett,2 J. Sweney,2 C. Myrick,1 S. Bratton.2

    1Intermountain Donor Services, Salt Lake City, UT; 2Pediatrics, University of Utah, Salt Lake City, UT.

    BACKGROUND AND OBJECTIVES: Organ donation after circulatory determination of death (DCDD) is increasing. DCDD offers potential for additional abdominal organ donation. We evaluated all dying…
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