Articles tagged "NMR spectroscopy"

2022 American Transplant Congress
Non-Invasive Metabolite-Based Urine Signature Detects Over-Immunosuppression in Renal Transplant Recipients
S. Raghavendra Rao¹, C. Honrao¹, L. O. Rodrigues¹, C. Dong¹, K. Sonkar¹, J. Wolf¹, E. M. O'Day¹, D. R. Kuypers²
¹Olaris, Inc., Framingham, MA, ²Department of Nephrology and Renal Transplantation, University Hospitals, Leuven, Belgium
*Purpose: Managing complications related to over-immunosuppression represents a growing challenge in post-transplant care, with infections accounting for the second leading cause of death with functioning…
2021 American Transplant Congress
Estimated GFR by Serum Myo-inositol, Valine, Creatinine, and Cystatin-c Outperforms Current CKD-epi Equations in Renal Transplant Recipients
J. W. Meeusen¹, F. Stammler², J. Lieske³, M. Grassi², M. Shah⁴, E. Schiffer²
¹Cardiovascular Laboratory Medicine, Mayo Clinic, Rochester, MA, ²Research and Development, Numares, Boston, MA, ³Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ⁴Clinical Research, Numares, Boston, MA
*Purpose: Current estimated GFR (eGFR) equations using creatinine and/or cystatin C do no perform well in kidney transplant (KTx) recipients. Therefore, some large transplant programs…
2016 American Transplant Congress
Metabolomic Profiling of Individuals with Failing Kidney Allograft.
R. Bassi,^1,2 M. Niewczas,³ L. Biancone,⁵ S. Bussolino,⁵ A. Lin,⁴ A. Chandraker,⁶ P. Fiorina.^1,2
¹Nephrology, Boston Children's Hospital, Boston; ²Transplant Medicine, IRCCS San Raffaele Hospital, Milan, Italy; ³Genetics and Epidemiology, Joslin Diabetes Center, Boston; ⁴Radiology, Brigham and Women's Hospital, Boston; ⁵Nephrology and Transplantation, San Giovanni Battista Hospital, Turin, Italy; ⁶Transplantation Research Center, Brigham and Women's Hospital, Boston.
Alteration of certain metabolites may play a role in the pathophysiology of renal allograft disease. To explore metabolome abnormalities in individuals with a failing kidney…