2017 American Transplant Congress
Signal Inhibitory Regulatory Protein-α Regulates Pathologic Reactive Oxygen Species in Acute Kidney Injury.
Background: Ischemia reperfusion injury (IRI) is mediated by a complex cascade of pro-inflammatory and oxidative processes. We have reported that signal regulatory inhibitory protein (SIRP)-α…2017 American Transplant Congress
Nox4 and Oxidative Stress Mediate TGF-β1 Induced Human Kidney Proximal Cell Apoptosis in Ischemic Reperfusion Injury.
AimsIschemia/reperfusion injury, resulting from hypoxic damage within a graft, is the leading cause of cell death and graft rejection. In this study, we investigated whether…2015 American Transplant Congress
Alloantibody-Dependent Macrophage-Mediated Hepatocellular Damage Is Dependent on FcγRI, FcγRIII, and Reactive Oxygen Species
Dept of Surgery, CTC, The Ohio State University Wexner Medical Center, Columbus, OH.
Alloantibodies (alloAb) play a critical role in rejection after transplantation. Despite this, the cellular mechanisms contributing to alloAb-mediated allograft damage are not well understood. Using…
American Transplant Congress abstracts