Articles tagged "N/A"

2022 American Transplant Congress
Impact of Donor Type, Cold Ischemia Time, and Induction Type on Baseline Donor-Derived Cell-Free DNA in Kidney Transplant Recipients
K. K. Sureshkumar¹, A. Grazier², B. Chopra¹
¹Nephrology, Medicine Institute, Allegheny General Hospital, Pittsburgh, PA, ²Abdominal Transplantation, Allegheny General Hospital, Pittsburgh, PA
*Purpose: Donor derived cell free DNA (dd-cfDNA) is a biomarker useful in predicting acute rejection in kidney allografts. Baseline dd-cfDNA levels are
2021 American Transplant Congress
Clinical Correlation of Frailty Measures and Evaluation of Complementary Molecular Frailty Biomarker Candidates in a Prospective National Cohort of Liver Transplant Candidates
S. Cremen¹, M. Robinson², T. Gallagher¹
¹Department of Hepatobiliary and Transplant Surgery, St Vincent's University Hospital, Dublin, Ireland, ²Department of Biology, Maynooth University, Kildare, Ireland
*Purpose: Frailty is a clinical condition characterized by a loss of physiologic reserve and increased susceptibility to stressors. Molecular frailty biomarkers may reflect the dysregulation…
2021 American Transplant Congress
Characterization of Kidney Small Extracellular Vesicles Released During Normothermic Machine Perfusion
W. W. Woud¹, A. Arykbaeva², D. de Vries², I. Alwayn², K. Boer¹, C. Baan¹, M. Hoogduijn¹, R. Minnee³
¹Internal Medicine, Nephorology and Transplantation, Erasmus MC, Rotterdam, Netherlands, ²Department of Surgery, LUMC, Leiden, Netherlands, ³Department of Surgery, Division of Hepato-Pancreato-Biliary and Transplant Surgery, Erasmus MC, Rotterdam, Netherlands
*Purpose: By characterizing and quantifying the dynamical release of kidney Extracellular Vesicles (EVs) during Normothermic Machine Perfusion (NMP), we aim to gain a better understanding…
2021 American Transplant Congress
Modeling of Alternative Weight-Based Dosing Strategies of LCP-Tacrolimus in De Novo Kidney Transplant Patients
J. D. Momper¹, S. J. Patel², M. A. Moten², D. R. Stevens², U. Meier-Kriesche²
¹Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, ²Medical Affairs, Veloxis Pharmaceuticals, Cary, NC
*Purpose: LCP-tacrolimus (LCPT; Envarsus XR®) is a modified-release once-daily formulation approved for prophylaxis of organ rejection in de novo kidney transplant patients in combination with…
2021 American Transplant Congress
Use of a Novel Bead-based Assay to Measure the Impact of Imlifidase on ABO IgG Antibodies
A. Halpin¹, B. Motyka², T. Ellis², J. Pearcey², T. L. Lowary³, A. Runström⁴, L. Winstedt⁴, R. Bockermann⁴, S. Järnum⁴, A. Robertson⁴, L. J. West⁵
¹Department of Pediatrics and Laboratory Medicine and Pathology, University of Alberta and Alberta Precision Laboratories, Edmonton, AB, Canada, ²Department of Pediatrics, University of Alberta, Edmonton, AB, Canada, ³Department of Chemistry, University of Alberta, Edmonton, AB, Canada, ⁴Hansa Biopharma, Lund, Sweden, ⁵Department of Pediatrics and Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada
*Purpose: The accurate assessment and measurement of ABO antibodies (ABO-Ab) is a critical component of ABO-incompatible (ABOi) transplantation. ABO-Ab comprise both IgG and IgM, which…
2021 American Transplant Congress
Normothermic-Hyperthermic Machine Perfusion Could Increase Response to Pharmacological Intervention in Mitigation of Liver Steatosis
F. Zhou, M. Xu, G. A. Upadhya, Y. Lin, W. C. Chapman
Surgery, Washington University in St. Louis, St. Louis, MO
*Purpose: To study the feasibility of mitigating rat liver steatosis with ex-situ normothermic-hyperthermic machine perfusion using a multi-drug ‘defatting’ combination.*Methods: 16 male Zucker obese rats…
2021 American Transplant Congress
Anterior Rectus Sheath versus Gibson Incision for Kidney Transplantation – University of Chicago Experience
G. S. Generette, P. J. Bachul, P. E. Borek, K. Jayant, A. Perez-Gutierrez, B. Juengel, Y. T. Becker, R. Barth, J. Fung, P. Witkowski
Surgery, University of Chicago, Chicago, IL
*Purpose: The advantages of Anterior Rectus Sheath (ARS) incision over traditional Gibson (GB) incision have been described for kidney transplantation. Therefore, we decided to compare…
2021 American Transplant Congress
Results of the APP Practice Survey: Do APPs Practice at the Top of Their Scope of Practice?
H. Domingo¹, D. Krieger², B. Muth³, A. Frank⁴, A. Borth⁵, H. McDade⁵, K. Paolini⁶, A. Mayfield⁵, M. Siegfired⁷, J. Yoo⁸, H. Hoy⁹, N. McCormick¹⁰
¹Northwestern University, Chicago, IL, ²University of California-San Francisco, San Francisco, CA, ³University of Wisconsin, Madison, WI, ⁴Medstar Georgetown University, Annandale, VA, ⁵University of Maryland, Baltimore, MD, ⁶Erie County Medical Center, Grand Island, NY, ⁷Swedish Organ Transplant, Seattle, WA, ⁸Rush University, Chicago, IL, ⁹University of Alabama - Huntsville, Huntsville, AL, ¹⁰University of Colorado-Denver, Denver, CO
*Purpose: Transplant centers employ Advance Practice Providers (APPs) in response to physician trainee work hour restrictions and to increase patient access to transplant care. APPs…
2021 American Transplant Congress
Identification and Comprehensive Validation of Prognostic Genes After Ischemic and Reperfusion Injury Across Different Donor Types in Renal Transplantation
D. Zhang, Y. Wang, Y. Wang, X. Hu
Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
*Purpose: Ischemic and reperfusion injury (IRI) remains an inevitable and major challenge for renal transplant patients. The current study aims to obtain overall insights into…
2021 American Transplant Congress
Development and Validation of a Nomogram for Remnant Kidney Function After Living-donor Donation
M. Dou, P. Tian, B. Zheng, G. Deng, Y. Shi, C. Ding
The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China
*Purpose: This study was to develop and validate a nomogram to predict remnant kidney function after living-donor kidney donation.*Methods: We conducted a retrospective cohort study…