2022 American Transplant Congress
Establishing a Framework for Long-Term Follow-Up: A Survey of Perspectives and Preferences of Living Kidney Donors
*Purpose: There is currently no established standard for long-term follow-up of living kidney donors in Canada. To inform a new national standard, we sought to…2022 American Transplant Congress
Real-Life Tacrolimus Levels Are Associated with Biopsy-Proven Acute Rejection After the First Year Post-Kidney Transplantation
*Purpose: Evidence to recommend specific target concentrations for immunosuppression beyond the first year of kidney transplantation (KT) is limited. We correlated real-life exposure data of…2022 American Transplant Congress
Creating a Workflow for the Electronic Medical Record Allows Living Donor Liver Transplantation Programs to Track Candidates and Identify Areas for Optimization
1Yale University School of Medicine, New Haven, CT, 2Yale New Haven Hospital, New Haven, CT
*Purpose: To provide a pathway to increase living donor liver transplantation (LDLT) opportunities through creation of a simple workflow algorithm embedded within the EPIC electronic…2022 American Transplant Congress
Measurement of Physical Activity and Frailty in the Early Post-Operative Period After Liver Transplant Surgery: Single-Center Pilot Study Using Fitbit Watch
Henry Ford Transplant Institute, Detroit, MI
*Purpose: Robust physical activity after liver transplant (LT) is an important determinant of long-term health. Patient and providers assessments of perioperative physical activity do not…2022 American Transplant Congress
Discordant Histological Findings During Acute Rejection in a Combined Face and Hand Transplant Recipient
*Purpose: The purpose of this study is to evaluate histologic findings in a face and bilateral hand transplant recipient that was monitored with multi-site allograft…2022 American Transplant Congress
Critical Care of the Brain-Dead Recipient of a Pig-to-Human Renal Transplant
1NYU Langone Transplant Institute, New York, NY, 2NYU Langone Health, New York, NY
*Purpose: The care of a brain dead (BD) patient undergoing xenotransplantation in a non-clinical environment poses unique challenges. Selection of an appropriate decedent, stabilization of…2021 American Transplant Congress
Tacrolimus Therapeutic Exposure is Not Consistently Predicted by Target Troughs or CYP3A5 Variants in Stable Renal Transplant Recipients
*Purpose: Tacrolimus (TAC) immunosuppression requires therapeutic trough monitoring post-transplant due to notable interpatient pharmacokinetic(PK) variability which may be attributed to CYP3A5 polymorphisms. We investigated the…2021 American Transplant Congress
Role of Serial Donor Derived Cell-Free DNA Monitoring in Kidney Transplant Recipients
Nephrology, Stanford University School of Medicine, Palo Alto, CA
*Purpose: Donor derived cell-free DNA (dd cf-DNA; Allosure, CareDx) is increasingly employed for non-invasive kidney transplant monitoring. The goal of this study was 1) to…2021 American Transplant Congress
The Clinical Validation of a Dried Blood Spot Method for Simultaneous Tacrolimus and Creatinine Measurement
*Purpose: Monitoring tacrolimus concentrations and kidney function after transplantation is important to avoid tacrolimus under- and overexposure and its clinical consequences, including acute nephrotoxicity. Using…2021 American Transplant Congress
Donor Derived Cell-free DNA Kinetics Early After Kidney Transplant in Patients with Delayed Graft Function Who Received Kidneys from Donation After Cardiac Death Donors
Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: Delayed graft function (DGF) may reduce long-term kidney allograft survival due to ischemia-reperfusion injury and rejection. Donor Derived Cell-Free DNA (dd-cfDNA) is proposed to…
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