Articles tagged "Monitoring"

2022 American Transplant Congress
Results of a Pilot Adherence Activity for Pharmacy Learners on a Solid Organ Transplant Service
J. Zumbrunnen
Pharmacy, Emory University Hospital, Atlanta, GA
*Purpose: The purpose was to determine if the ability of pharmacy learners to educate patients and help overcome barriers to medication adherence is improved after…
2022 American Transplant Congress
The Development of a Scientific Registry of Transplant Recipients Data Query Tool: A Human-Centered Design Process
C. Schaffhausen¹, A. Hart², C. S. Zinner³, A. K. Israni², J. Snyder¹
¹Hennepin Healthcare Research Institute, Minneapolis, MN, ²Hennepin Healthcare (HHS) / University of Minnesota (UMN), Minneapolis, MN, ³Accenture Federal Services, Washington, DC
*Purpose: The Scientific Registry of Transplant Recipients (SRTR) provides national transplant data in various forms, including the OPTN/SRTR Annual Data Report (ADR). The ADR includes…
2022 American Transplant Congress
Noninvasive Biomarkers for Allograft Monitoring After Intestinal Transplantation: Promising Early Results from a Novel Peptide, REG3α
C. P. Smullin¹, R. S. Venick², E. A. Marcus², B. V. Naini³, D. G. Farmer⁴
¹David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, ²Pediatrics, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, ³Pathology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, ⁴Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA
*Purpose: There is an urgent need for the discovery and application of noninvasive biomarkers to detect allograft rejection after intestinal transplantation (ITx). Calprotectin and citrulline…
2022 American Transplant Congress
Impact of the Covid-19 Pandemic on Longitudinal Molecular Surveillance in the KOAR Registry
T. Alhamad¹, A. Malone¹, D. Mandelbrot², P. M. Anand³, H. M. Wadei⁴, G. Shekhtman⁵, N. Agrawal⁵, K. Pinney⁵, K. Qu⁵, A. Desai⁶
¹Washington University, St. Louis, MO, ²University of Wisconsin, Madison, WI, ³Medical University of South Carolina, Charleston, SC, ⁴Mayo Clinic Jacksonville, Jacksonville, FL, ⁵CareDx, Brisbane, CA, ⁶Loyola University Medical Center, Maywood, IL
*Purpose: The SARS-CoV2 pandemic increased the complexity of delivering routine clinical care and laboratory services for immunosuppressed kidney transplant (KTx) recipients. We evaluated how the…
2022 American Transplant Congress
The Effect of Baseline Blood Pressure on Early Graft Function in Deceased Donor Kidney Transplantation
B. Jun Bae¹, C. Oh¹, H. Ahn²
¹Department of surgery, Ajou University Medical School, Suwon, Korea, Republic of, ²Department of Anesthesiology and Pain medicine, Ajou University Medical School, Suwon, Korea, Republic of
*Purpose: The adequate perfusion pressure to the graft is essential for proper graft function in kidney transplantation, especially in deceased donor kidney transplantation. Therefore, the…
2022 American Transplant Congress
Measurement of Physical Activity and Frailty in the Early Post-Operative Period After Kidney Transplant-Single-Center Prospective Pilot Study Using Fitbit Watch
T. Shamaa, L. Allenspach, O. Shamaa, S. Shimada, C. Crombez, O. Hage-Hassan, T. Kitajima, S. Yeddula, I. Bajjoka, L. Malinzak, J. Denny, D. Kim, M. Abouljoud, S. Nagai
Henry Ford Transplant Institute, Detroit, MI
*Purpose: Physical activity monitors (PAMs) allow patients to track multiple health parameters. PAM’s may be helpful to assess a patient’s physical recovery after a Kidney…
2022 American Transplant Congress
Utility of Donor Derived Cell-Free DNA in Liver Transplantation
A. Zarrinpar, D. Lewis, C. Warren, S. Duarte
Surgery, University of Florida, Gainesville, FL
*Purpose: As a non-invasive measure of allograft injury, quantifying the fraction of donor-derived cell-free DNA (dd-cfDNA) has proven to be useful technique in kidney transplantation.…
2022 American Transplant Congress
Early Experience with OmniGraf® Biomarker Surveillance in Kidney Transplant Patients in the First-Year Post-Transplant and Beyond
V. Paramasivam¹, W. Ally², B. Sivakumar³, B. Greco¹, M. Germain¹
¹Baystate Medical Center, Springfield, MA, ²Eurofins Transplant Genomics, Framingham, MA, ³Dartmouth College, Hanover, NH
*Purpose: Non-invasive rejection biomarkers continue to evolve with recent data supporting the use of combined gene expression and donor derived cell-free DNA (dd-cfDNA) in kidney…
2022 American Transplant Congress
Clinical Stratification of Pediatric Liver Transplant Recipients 4-5 Years Post-Transplant: 1^St Step Towards Personalized Management
W. Dixon¹, E. R. Perito¹, M. Tavakol¹, J. Bucuvalas², S. Feng¹
¹University of California, San Francisco, San Francisco, CA, ²Mount Sinai Kravis Children's Hospital and Recanati/Miller Transplantation Institute, Mount Sinai Health System, New York, NY
*Purpose: Recent surveillance biopsy studies strongly associate high normal ALT (>35U/L) with inflammatory histopathology and low normal ALT (15yrs (n=13; p=0.0006), chronic rejection (CR) diagnosis…
2022 American Transplant Congress
A Novel, High Throughput Droplet Digital PCR-Based Indel Quantification Method for the Detection of Circulating Donor-Derived Cell-Free DNA After Kidney Transplantation
J. G. Verhoeven¹, K. Boer¹, A. M. Peeters¹, M. C. Clahsen-van Groningen², J. I. Roodnat¹, J. van de Wetering¹, D. Nieboer³, D. A. Bost⁴, C. C. Baan¹, D. A. Hesselink¹
¹Department of Internal Medicine, Erasmus MC Transplant Institute, Rotterdam, Netherlands, ²Department of Pathology, University Medical Center Rotterdam, Rotterdam, Netherlands, ³Department of Public Health, University Medical Center Rotterdam, Rotterdam, Netherlands, ⁴JETA Molecular, Utrecht, Netherlands
*Purpose: Donor-derived cell-free DNA (ddcfDNA) is a promising minimally invasive biomarker for acute rejection (AR) in kidney transplant recipients. To assess the diagnostic value of…