Articles tagged "Monitoring"

2019 American Transplant Congress
The Impact of Removing DSA as a First Unit of Lung Allocation: Preliminary Results
R. R. Lehman¹, K. Uccellini², M. Skeans³, M. Valapour³, E. D. Lease⁴, R. Daly⁵, K. M. Chan⁶
¹Research, United Network for Organ Sharing, Richmond, VA, ²Policy, United Network for Organ Sharing, Richmond, VA, ³SRTR, Minneapolis, MN, ⁴Univ of Washington, Seattle, WA, ⁵Mayo Clinic, Rochester, MN, ⁶Univ of Michigan, Ann Arbor, MI
*Purpose: In an emergency action on November 24, 2017 the Organ Procurement and Transplantation Network (OPTN) altered US lung allocation policy by replacing the donor…
2019 American Transplant Congress
Non-Invasive Monitoring of the Kidney Allograft
S. Bontha¹, G. Darville¹, C. Kuscu¹, C. Kuscu², A. Bajwa¹, J. Eason³, D. Maluf⁴, V. Mas⁵
¹Surgery, UTHSC, Memphis, TN, ²Surgery, UTHSC, memphis, TN, ³Surgery, Director of Transplant Institute - UTHSC, Memphis, TN, ⁴UTHSC, Memphis, TN, ⁵Surgery, Director of Transplant Research Institute, Memphis, TN
*Purpose: A major issue in kidney transplantation is the lack of validated non-invasive biomarkers for monitoring graft function, current biochemical markers (i.e., creatinine) have poor…
2019 American Transplant Congress
Characterization Of Increased Risk Donor Post-transplant Viral Surveillance Protocol At A Comprehensive Transplant Center
J. Dann, W. Ally, S. Pelletier, C. Sifri, A. Agarwal
University of Virginia Health System, Charlottesville, VA
*Purpose: With the growing opioid crisis, the number of deceased donors classified as Increased Risk Donor (IRD) has increased to nearly 20% nationally. The Organ…
2019 American Transplant Congress
Elevated Podocyte-specific Urinary Extracellular Vesicles In Patients With Fsgs Recurrence After Kidney Transplantation
H. Lau, A. Shimomura, E. Tantisattamo, U. G. Reddy, D. Dafoe, H. Ichii
University of California Irvine, Orange, CA
*Purpose: Kidney graft failure is a major concern in patients with kidney transplantation. Patients who suffered graft failure are at a higher risk for mortality…
2019 American Transplant Congress
Monitoring Inflammatory Cytokine Levels in Kidney Transplant Patients (KTx Pts) with Chronic Antibody Mediated Rejection (cABMR) Treated with Clazakizumab (CLZ, Humanized Anti-IL-6 Monoclonal Antibody)
S. Ge¹, A. Petrosyan¹, M. Chu¹, N. Ammerman², A. Vo², S. C. Jordan², X. Zhang³, M. Toyoda¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA, ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, ³HLA Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: IL-6 is a pro-inflammatory cytokine involved in KTx rejection. A clinical trial to improve cABMR using CLZ in HLA-sensitized KTx Pts is underway. Inhibition…
2019 American Transplant Congress
A Cytomegalovirus Antiviral Stewardship Program at a Large Transplant Center
M. Jorgenson¹, J. Descourouez¹, D. Felix¹, C. Saddler², J. Smith², D. Mandelbrot²
¹UW Health, Madison, WI, ²University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI
*Purpose: The purpose of this study was to determine the feasibility and scope of a multidisciplinary cytomegalovirus Antiviral Stewardship Program.*Methods: The principles of antimicrobial stewardship…
2019 American Transplant Congress
The Evolving Clinical Presentation of Acute Rejection in Face Transplantation
V. Haug, B. Kollar, D. Obed, H. Kiwanuka, M. Turk, L. Wo, S. Tasigiorgos, M. Kueckelhaus, L. Riella, B. Pomahac
Plastic and Reconstructive Surgery, Brigham and Women's Hospital, Boston, MA
*Purpose: Clinical signs such as erythema or edema are traditionally helpful to diagnose Acute rejection (AR) in face transplantation (FT) in the early follow-up. The…
2019 American Transplant Congress
Donor-Derived Cell-Free DNA is Associated Specifically with Antibody Mediated Injury in Patients with Renal Allograft Dysfunction
B. Obrisca¹, C. Blosser², I. De Castro², C. Johnson², B. Sorohan¹, L. Sibulesky², R. Bakthavatsalam², G. Ismail¹, N. Leca²
¹Fundeni Clinical Institute, Bucharest, Romania, ²University of Washington, Seattle, WA
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) has been proposed as a noninvasive biomarker to differentiate rejection from other types of injury in renal allografts.*Methods: We analyzed…
2019 American Transplant Congress
Perception Of Hospital Staff On Transplant: Pre And Post-intervention
J. Wise¹, A. Sarvestani¹, K. Briggs², J. Malik², M. Ott³, L. Markham³, H. Wilkins³, D. Neel², C. Richart⁴, J. Foxworth¹, M. Moncure²
¹University of Missouri - Kansas City, Kansas City, MO, ²Department of Surgery, University of Missouri - Kansas City, Kansas City, MO, ³Midwest Transplant Network, Kansas City, MO, ⁴Northeast Georgia Medical Center, Gainesville, GA
*Purpose: A primary component in managing potential organ donors is working effectively and collaboratively in the multidisciplinary environment of the ICU. Fundamentals of Critical Care…
2019 American Transplant Congress
Four-Year Follow Up of Kidney Transplantation Using Alemtuzumab Induction and Belatacept/Sirolimus Maintenance Therapy
A. Kirk¹, H. Xu¹, A. Ghali², A. Mehta², A. Guasch²
¹Surgery, Duke University, Durham, NC, ²Transplant Center, Emory University, Atlanta, GA
*Purpose: Kidney transplantation remains limited by the chronic toxicities associated with calcineurin inhibitors (CNIs) and steroids. The objective of this clinical trial was to determine…